Publications

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Azzazi, Y., H. Khedr, and M. R. E. Abdel-Halim, "Pigmented colloid milium in a beta-thalassemia major patient: a case report.", International journal of dermatology, vol. 62, issue 12, pp. e626-e628, 2023.
Adel, A., M. R. E. Abdel-Halim, and Y. Abdel-Galeil, "Ulcerated Nipple Nodule, Clinicopathologic Challenge: Challenge.", The American Journal of dermatopathology, 2020.
Abdelkader, H. A., M. M. Fawzy, N. Nour, and M. R. E. Abdel-Halim, "Eczematous mucinous eccrine nevus: a novel presentation with Meyerson phenomenon.", International journal of dermatology, 2022.
Abdelkader, H. A., Y. Abdel-Galeil, A. Elbendary, M. El-Mofty, and M. R. E. Abdel-Halim, "Multiple Skin Ulcers in a Rheumatoid Arthritis Patient: Challenge.", The American Journal of dermatopathology, vol. 42(2), pp. e20-e21, 2018 Dec 07, 2020.
Abdelkader, H. A., J. Hamdan, A. Elbendary, and M. R. E. Abdel-Halim, "Papillary eccrine adenoma presenting as a cutaneous horn.", International journal of dermatology, 2021.
AbdElhalim, M., M. Fawzy, M. Saleh, S. Ismail, S. Doss, E. El Nabarawy, A. E. L. Tawdy, M. A. Latif, S. Shalaby, M. Amer, et al., "Unilateral facial papules and plaques", Cutis, vol. 103, issue 4, pp. 198-, 201-202, 2019.
Abdel-Halim, M. R. E., A. Mahmoud, and G. Ragab, "Cutaneous manifestations of ANCA associated vasculitis", Vessel Plus, vol. 6, 2022.
Abdel-Halim, M. R. E., E. El Nabarawy, A. El-Tawdy, G. El-Enany, M. Soliman, H. Weshahy, H. A. S. Fayed, and R. Hegazy, "Sclerotic Ulcerated Plaque on the Back.", The American Journal of dermatopathology, vol. 41, issue 4, pp. 314-315, 2018 Apr 11, 2019.
Abdel-Halim, M. R. E., M. M. Fawzy, M. A. Saleh, S. Ibrahim, E. El Nabarawy, A. E. L. Tawdy, M. A. El-latif, S. Shalaby, M. Amer, M. S. El Hawary, et al., "What is your diagnosis? Clinicopathological correlation", Journal of the Egyptian Women’s Dermatologic Society, vol. 12, no. 2: LWW, pp. 142–143, 2015. Abstract
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Abdel-Halim, M., E. El-Nabarawy, M. D. Reham El Nemr, and A. M. Hassan, "Frequency of Hypopigmented Mycosis Fungoides in Egyptian Patients Presenting With Hypopigmented Lesions of the Trunk.", The American Journal of Dermatopathology: LWW, 2015. Abstract
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Abdel-Halim, M. R. E., E. El-Nabarawy, A. El-Tawdy, M. M. Fawzy, S. Shalaby, S. Ismail, and M. Amer, "Leonine facies and neck papules.", International journal of dermatology, 2019.
Abdel-Halim, M. R. E., M. Fawzy, M. A. Saleh, S. Ismail, S. Doss, E. El Nabarawy, A. E. L. Tawdy, M. A. El-latif, S. Shalaby, M. Amer, et al., "Linear unilateral basal cell nevus with comedones (linear nevoid basaloid follicular hamartoma): a case report.", JEWDS, vol. 13, no. 1, pp. 46–48, 2016. Abstract
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Abdel-Aal, R. E., M. R. E. Abdel-Halim, and S. Abdel-Aal, "Improving the classification of multiple disorders with problem decomposition", Journal of biomedical informatics, vol. 39, no. 6: Elsevier, pp. 612–625, 2006. Abstract
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Abdalla, D., M. Bosseila, M. R. E. Abdel-Halim, and I. Sany, "Peripilar Sign in Androgenetic Alopecia: Does It Really Indicate Peripilar Infiltrate?", Dermatology practical & conceptual, vol. 14, issue 1, 2024. Abstract

INTRODUCTION: Peripilar sign (PPS) is a trichoscopic sign that was first described in androgenetic alopecia (AGA) and is thought to reflect the presence of perifollicular infiltrate (PFI) in histopathology.

OBJECTIVES: To study PPS in a cohort of patients with AGA and to assess its validity as a sign indicative of PFI.

METHODS: One hundred patients with AGA (confirmed by trichoscopic examination) were recruited in this cross-sectional study. From those patients, frontal scalp biopsy was done for two subgroups, 22 patients with PPS and 23 patients without PPS. Both groups were compared as regards the presence of PFI.

RESULTS: Peripilar sign was present in 50% of the 100 studied cases. No significant difference existed between those with and those without PPS as regards PFI. Peripilar sign was significantly more encountered in patients with skin type III (p=0.001). Its absence was significantly associated with lower interpretability of yellow dots (p<0.001) and their scores were significantly positively correlated (r=0.498, p<0.001). Peripilar sign was significantly associated with absent melanophages histopathologically (p=0.011).

CONCLUSION: Peripilar sign as a trichoscopic sign in AGA does not reflect PFI. It represents a dark color more encountered in patients with lighter skin types. This can be explained by the increased contrast between the dark PPS and the lighter surrounding skin in lighter skin types. Further studies using melanocyte markers and Masson Fontana's stain are needed to further verify the cause of this peri-follicular dark color.

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