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A
Abdalla, D., M. Bosseila, M. R. E. Abdel-Halim, and I. Sany, "Peripilar Sign in Androgenetic Alopecia: Does It Really Indicate Peripilar Infiltrate?", Dermatology practical & conceptual, vol. 14, issue 1, 2024. Abstract

INTRODUCTION: Peripilar sign (PPS) is a trichoscopic sign that was first described in androgenetic alopecia (AGA) and is thought to reflect the presence of perifollicular infiltrate (PFI) in histopathology.

OBJECTIVES: To study PPS in a cohort of patients with AGA and to assess its validity as a sign indicative of PFI.

METHODS: One hundred patients with AGA (confirmed by trichoscopic examination) were recruited in this cross-sectional study. From those patients, frontal scalp biopsy was done for two subgroups, 22 patients with PPS and 23 patients without PPS. Both groups were compared as regards the presence of PFI.

RESULTS: Peripilar sign was present in 50% of the 100 studied cases. No significant difference existed between those with and those without PPS as regards PFI. Peripilar sign was significantly more encountered in patients with skin type III (p=0.001). Its absence was significantly associated with lower interpretability of yellow dots (p<0.001) and their scores were significantly positively correlated (r=0.498, p<0.001). Peripilar sign was significantly associated with absent melanophages histopathologically (p=0.011).

CONCLUSION: Peripilar sign as a trichoscopic sign in AGA does not reflect PFI. It represents a dark color more encountered in patients with lighter skin types. This can be explained by the increased contrast between the dark PPS and the lighter surrounding skin in lighter skin types. Further studies using melanocyte markers and Masson Fontana's stain are needed to further verify the cause of this peri-follicular dark color.

Abdel-Aal, R. E., M. R. E. Abdel-Halim, and S. Abdel-Aal, "Improving the classification of multiple disorders with problem decomposition", Journal of biomedical informatics, vol. 39, no. 6: Elsevier, pp. 612–625, 2006. Abstract
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Abdel-Halim, M. R. E., E. El Nabarawy, A. El-Tawdy, G. El-Enany, M. Soliman, H. Weshahy, H. A. S. Fayed, and R. Hegazy, "Sclerotic Ulcerated Plaque on the Back.", The American Journal of dermatopathology, vol. 41, issue 4, pp. 314-315, 2018 Apr 11, 2019.
Abdel-Halim, M. R. E., M. Fawzy, M. A. Saleh, S. Ismail, S. Doss, E. El Nabarawy, A. E. L. Tawdy, M. A. El-latif, S. Shalaby, M. Amer, et al., "Linear unilateral basal cell nevus with comedones (linear nevoid basaloid follicular hamartoma): a case report.", JEWDS, vol. 13, no. 1, pp. 46–48, 2016. Abstract
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Abdel-Halim, M., E. El-Nabarawy, M. D. Reham El Nemr, and A. M. Hassan, "Frequency of Hypopigmented Mycosis Fungoides in Egyptian Patients Presenting With Hypopigmented Lesions of the Trunk.", The American Journal of Dermatopathology: LWW, 2015. Abstract
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Abdel-Halim, M. R. E., A. Mahmoud, and G. Ragab, "Cutaneous manifestations of ANCA associated vasculitis", Vessel Plus, vol. 6, 2022.
Abdel-Halim, M. R. E., and D. Salem, ASSESSMENT OF BONE MINERAL DENSITY BY DUAL X-RAY ABSORPTIOMETRY (DXA) IN DERMATOLOGICAL PATIENTS TREATED BY CORTICOSTEROIDS, , 2008. Abstract

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Abdel-Halim, M. R. E., E. El-Nabarawy, A. El-Tawdy, M. M. Fawzy, S. Shalaby, S. Ismail, and M. Amer, "Leonine facies and neck papules.", International journal of dermatology, 2019.
Abdel-Halim, M. R. E., M. M. Fawzy, M. A. Saleh, S. Ibrahim, E. El Nabarawy, A. E. L. Tawdy, M. A. El-latif, S. Shalaby, M. Amer, M. S. El Hawary, et al., "What is your diagnosis? Clinicopathological correlation", Journal of the Egyptian Women’s Dermatologic Society, vol. 12, no. 2: LWW, pp. 142–143, 2015. Abstract
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AbdElhalim, M., M. Fawzy, M. Saleh, S. Ismail, S. Doss, E. El Nabarawy, A. E. L. Tawdy, M. A. Latif, S. Shalaby, M. Amer, et al., "Unilateral facial papules and plaques", Cutis, vol. 103, issue 4, pp. 198-, 201-202, 2019.
Abdelkader, H. A., M. M. Fawzy, N. Nour, and M. R. E. Abdel-Halim, "Eczematous mucinous eccrine nevus: a novel presentation with Meyerson phenomenon.", International journal of dermatology, 2022.
Abdelkader, H. A., J. Hamdan, A. Elbendary, and M. R. E. Abdel-Halim, "Papillary eccrine adenoma presenting as a cutaneous horn.", International journal of dermatology, 2021.
Abdelkader, H. A., Y. Abdel-Galeil, A. Elbendary, M. El-Mofty, and M. R. E. Abdel-Halim, "Multiple Skin Ulcers in a Rheumatoid Arthritis Patient: Challenge.", The American Journal of dermatopathology, vol. 42(2), pp. e20-e21, 2018 Dec 07, 2020.
Adel, A., M. R. E. Abdel-Halim, and Y. Abdel-Galeil, "Ulcerated Nipple Nodule, Clinicopathologic Challenge: Challenge.", The American Journal of dermatopathology, 2020.
Azzazi, Y., H. Khedr, and M. R. E. Abdel-Halim, "Pigmented colloid milium in a beta-thalassemia major patient: a case report.", International journal of dermatology, vol. 62, issue 12, pp. e626-e628, 2023.
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El Darouti, M., S. A. Marzouk, M. Fawzi, M. Rabie, A. El Tawdi, and M. Abdel Azziz, "Reticulate acropigmentation of Dohi: a report of two new associations", International journal of dermatology, vol. 43, no. 8: Wiley Online Library, pp. 595–596, 2004. Abstract
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El Darouti, M. A., S. A. Marzouk, H. M. Mashaly, E. A. El Nabarawi, M. R. E. Abdel-Halim, M. M. El Komy, V. G. Hafez, A. H. M. Reheem, and K. M. Moussa, "Lipedema and lipedematous alopecia: report of 10 new cases (vol 17, pg 351, 2007)", EUROPEAN JOURNAL OF DERMATOLOGY, vol. 17, no. 5: JOHN LIBBEY EUROTEXT LTD 127 AVE DE LA REPUBLIQUE, 92120 MONTROUGE, FRANCE, pp. 360–360, 2007. Abstract
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El Mofty, M. A., R. M. Youssef, S. O. Tawfic, M. R. E. Abdel Halim, H. Abozeid, O. G. Shaker, and O. M. Mohammad, "Skin and serum levels of calcium, phosphorus and vitamin D3 in uremic pruritus patients before and after broad band ultraviolet B (UVB) phototherapy", Egypt Dermatol Online J, vol. 2, 2006. Abstract
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El-Darouti, M. A., S. A. Marzouk, and M. R. E. Abdel-Halim, "Muckle–Wells syndrome: report of six cases with hyperpigmented sclerodermoid skin lesions", International journal of dermatology, vol. 45, no. 3: Wiley Online Library, pp. 239–244, 2006. Abstract
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El-Darouti, M. A., S. A. Fawzi, S. A. Marzook, N. H. El-Eishi, M. R. E. Abdel-Halim, and S. A. Soliman, "Familial gigantic melanocytosis", International journal of dermatology, vol. 44, no. 12: Wiley Online Library, pp. 1010–1015, 2005. Abstract
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El-Darouti, M. A., S. Hussein, S. A. Marzouk, N. Nabil, N. S. Hunter, D. Mahgoub, N. H. El-Eishi, and M. R. E. Abdel-Halim, "Histopathological study of apparently normal skin of patients with leprosy", International journal of dermatology, vol. 45, no. 3: Wiley Online Library, pp. 292–296, 2006. Abstract
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El-Darouti, M. A., S. A. Marzouk, M. Bosseila, O. abu Zeid, O. El-Safouri, A. Zayed, A. El-Ramly, and M. R. E. Abdel-Halim, "Microscopic study of normal skin in cases of mycosis fungoides", International journal of dermatology, vol. 45, no. 9: Wiley Online Library, pp. 1043–1046, 2006. Abstract
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El-Darouti, M. A., S. A. Marzouk, M. H. M. El-Komy, and M. RE, "Preliminary Clinical, Histopathological and Laboratory Study of Cases Presenting with Pruriginous Edematous Excoriated Papular Eruption (Subacute Prurigo)", Kasr Al Aini Medical Journal, vol. 13, no. 1, pp. 7–13, 2007. Abstract
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El-Darouti, M. A., S. A. Marzouk, M. R. E. Abdel-Halim, A. Z. Zidan, and M. M. Fawzy, "Basaloid follicular hamartoma", International journal of dermatology, vol. 44, no. 5: Wiley Online Library, pp. 361–365, 2005. Abstract
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El-Darouti, M. A., H. M. Mashaly, E. El-Nabarawy, A. M. Eissa, M. R. E. Abdel-Halim, M. M. T. Fawzi, N. H. El-Eishi, S. O. Tawfik, N. S. Zaki, A. Z. Zidan, et al., "Leukocytoclastic vasculitis and necrolytic acral erythema in patients with hepatitis C infection: Do viral load and viral genotype play a role?", Journal of the American Academy of Dermatology, vol. 63, no. 2: Elsevier, pp. 259–265, 2010. Abstract
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