Publications

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2024
Abdel-Haleem, A. H., M. A. Ellafy, S. E. S. Abbas, and M. K. El-Ashrey, "Design, synthesis and anticancer evaluation of some novel 7-hydroxy-4-methyl-3-substituted benzopyran-2-one derivatives", Future Medicinal Chemistry: Newlands Press Ltd London, UK, 2024. Abstract
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Abdel-Sattar, E., O. Kutkat, R. A. El-Shiekh, M. K. El-Ashrey, and A. M. El Kerdawy, "In Silico and In Vitro Screening of Some Pregnane Glycosides Isolated from Certain Caralluma Species as SARS-COV-2 Main Protease Inhibitors", Chemistry & Biodiversity, vol. 21, no. 4, pp. e202301786, 2024. Abstract
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Elshibani, F. A., A. D. Alamami, H. A. Mohammed, R. A. Rasheed, R. M. El Sabban, M. A. Yehia, S. S. Abdel Mageed, T. A. Majrashi, E. B. Elkaeed, M. A. El Hassab, et al., "A multidisciplinary approach to the antioxidant and hepatoprotective activities of Arbutus pavarii Pampan fruit; in vitro and in Vivo biological evaluations, and in silico investigations", Journal of Enzyme Inhibition and Medicinal Chemistry, vol. 39, no. 1: Taylor & Francis, pp. 2293639, 2024. Abstract
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Eldehna, W. M., S. T. Mahmoud, E. R. Elshnawey, Z. M. Elsayed, T. A. Majrashi, M. K. El-Ashrey, M. Rashed, L. R. Hemeda, A. A. Shoun, E. B. Elkaeed, et al., "Novel indolinone-tethered benzothiophenes as anti-tubercular agents against MDR/XDR M. tuberculosis: Design, synthesis, biological evaluation and in vivo pharmacokinetic study", Bioorganic Chemistry, vol. 143: Academic Press, pp. 107009, 2024. Abstract
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Elhabal, S. F., N. Abdelaal, S. A. E. E. D. A. S. AL-ZUHAIRY, M. F. M. Elrefai, M. M. Khalifa, M. A. Khasawneh, A. M. Elsaid Hamdan, P. M. Mohie, R. A. Gad, S. L. Kabil, et al., "Revolutionizing Psoriasis Topical Treatment: Enhanced Efficacy Through Ceramide/Phospholipid Composite Cerosomes Co-Delivery of Cyclosporine and Dithranol: In-Vitro, Ex-Vivo, and in-Vivo Studies", International Journal of Nanomedicine: Taylor & Francis, pp. 1163–1187, 2024. Abstract
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2023
Al-Warhi, T., H. Almahli, R. M. Maklad, Z. M. Elsayed, M. A. El Hassab, O. J. Alotaibi, N. Aljaeed, R. R. Ayyad, H. A. Ghabour, W. M. Eldehna, et al., "1-Benzyl-5-bromo-3-hydrazonoindolin-2-ones as Novel Anticancer Agents: Synthesis, Biological Evaluation and Molecular Modeling Insights", Molecules, vol. 28, no. 7: MDPI, pp. 3203, 2023. Abstract
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Ibrahim, K. A., M. K. El-Ashrey, M. O. N. A. T. KASHEF, and O. M. N. E. Y. A. M. HELMY, "Alanine racemase a promising Helicobacter pylori drug target inhibited by propanoic acid", Microbes and Infection, vol. 25, no. 7: Elsevier Masson, pp. 105167, 2023. Abstract
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Hemeda, L. R., M. A. El Hassab, M. O. H. A. M. E. D. A. ABDELGAWAD, E. F. Khaleel, M. M. Abdel-Aziz, F. A. Binjubair, S. T. Al-Rashood, W. M. Eldehna, and M. K. El-Ashrey, "Discovery of pyrimidine-tethered benzothiazole derivatives as novel anti-tubercular agents towards multi-and extensively drug resistant Mycobacterium tuberculosis", Journal of Enzyme Inhibition and Medicinal Chemistry, vol. 38, no. 1: Taylor & Francis, pp. 2250575, 2023. Abstract
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El-Hussieny, M., M. A. Abd-El-Maksoud, F. M. Soliman, M. A. Fouad, and M. K. El-Ashrey, "Dual-target ligand discovery for Alzheimer’s disease: triphenylphosphoranylidene derivatives as inhibitors of acetylcholinesterase and $\beta$-amyloid aggregation", Journal of Enzyme Inhibition and Medicinal Chemistry, vol. 38, no. 1: Taylor & Francis, pp. 2166040, 2023. Abstract
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El-Hussieny, M., M. A. Abd-El-Maksoud, F. M. Soliman, M. A. Fouad, and M. K. El-Ashrey, "Dual-target ligand discovery for Alzheimer’s disease: triphenylphosphoranylidene derivatives as inhibitors of acetylcholinesterase and $\beta$-amyloid aggregation", Journal of Enzyme Inhibition and Medicinal Chemistry, vol. 38, no. 1: Taylor & Francis, pp. 2166040, 2023. Abstract
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Ghamry, H. I., A. Belal, M. K. El-Ashrey, H. O. Tawfik, R. I. Alsantali, A. J. Obaidullah, A. A. El-Mansi, and D. A. Rahman, "Evaluating the ability of some natural phenolic acids to target the main protease and AAK1 in SARS COV-2", Scientific Reports, vol. 13, no. 1: Nature Publishing Group UK London, pp. 7357, 2023. Abstract
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ElNaggar, M. H., A. A. Elgazar, G. Gamal, S. M. Hamed, Z. M. Elsayed, M. K. El-Ashrey, A. Abood, M. A. El Hassab, A. M. Soliman, R. A. El-domany, et al., "Identification of sulphonamide-tethered N-((triazol-4-yl) methyl) isatin derivatives as inhibitors of SARS-CoV-2 main protease", Journal of enzyme inhibition and medicinal chemistry, vol. 38, no. 1: Taylor & Francis, pp. 2234665, 2023. Abstract
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Mostafa, E. A., M. K. El-Ashrey, and S. T. Mahmoud, "An innovative combination of Box-Behnken design and ecofriendly approaches for the simultaneous determination of aspirin, clopidogrel, atorvastatin and rosuvastatin in their fixed-dose combination tablets", BMC chemistry, vol. 17, no. 1: Springer International Publishing Cham, pp. 164, 2023. Abstract
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Mohamed, A. R., A. Mostafa, M. A. El Hassab, G. M. Hedeab, S. H. Mahmoud, R. F. George, H. H. Georgey, N. A. M. Gawad, and M. K. El-Ashrey, "Insights into targeting SARS-CoV-2: design, synthesis, in silico studies and antiviral evaluation of new dimethylxanthine derivatives", RSC Medicinal Chemistry, vol. 14, no. 5: Royal Society of Chemistry, pp. 899–920, 2023. Abstract
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Ghanem, A., M. A. Ali, M. A. Elkady, S. A. S. Mageed, M. A. El Hassab, M. K. El-Ashrey, O. A. Mohammed, and A. S. Doghish, "Rumex vesicarius L. boosts the effectiveness of sorafenib in triple-negative breast cancer by downregulating BCl2, mTOR, and JNK, and upregulating p21 expression", Pathology-Research and Practice, vol. 250: Urban & Fischer, pp. 154807, 2023. Abstract
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Elebeedy, D., A. Ghanem, S. H. Aly, M. A. Ali, A. H. I. Faraag, M. K. El-Ashrey, A. M. salem, M. E. A. Hassab, and A. A. E. I. Maksoud, "Synergistic antiviral activity of Lactobacillus acidophilus and Glycyrrhiza glabra against Herpes Simplex-1 Virus (HSV-1) and Vesicular Stomatitis Virus (VSV): experimental and In Silico insights", BMC microbiology, vol. 23, no. 1: BioMed Central London, pp. 173, 2023. Abstract
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2022
El-Sayed, N. N. E., N. M. Almaneai, A. Ben Bacha, M. K. El-Ashrey, M. I. Al-Zaben, and Z. M. Almarhoon, "Biological Evaluation, Molecular Docking Analyses, and ADME Profiling of Certain New Quinazolinones as Anti-colorectal Agents", ACS Omega: ACS Publications, 2022. Abstract
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El-Sayed, N. N. E., N. M. Almaneai, A. Ben Bacha, M. K. El-Ashrey, M. I. Al-Zaben, and Z. M. Almarhoon, "Biological Evaluation, Molecular Docking Analyses, and ADME Profiling of Certain New Quinazolinones as Anti-colorectal Agents", ACS omega, vol. 7, no. 22: American Chemical Society, pp. 18443–18458, 2022. Abstract
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El-Sayed, N. N. E., N. M. Almaneai, A. Ben Bacha, M. K. El-Ashrey, M. I. Al-Zaben, and Z. M. Almarhoon, "Biological Evaluation, Molecular Docking Analyses, and ADME Profiling of Certain New Quinazolinones as Anti-colorectal Agents", ACS omega, vol. 7, no. 22: American Chemical Society, pp. 18443–18458, 2022. Abstract
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El-Deen, E. M. M., M. M. Anwar, A. A. Abd El-Gwaad, E. A. Karam, M. K. El-Ashrey, and R. R. Kassab, "Design and synthesis of some novel pyridothienopyrimidine derivatives and their biological evaluation as antimicrobial and anticancer agents targeting EGFR enzyme", Arabian Journal of Chemistry, vol. 15, no. 4: Elsevier, pp. 103751, 2022. Abstract
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El-Deen, E. M. M., M. M. Anwar, A. A. Abd El-Gwaad, E. A. Karam, M. K. El-Ashrey, and R. R. Kassab, "Design and synthesis of some novel pyridothienopyrimidine derivatives and their biological evaluation as antimicrobial and anticancer agents targeting EGFR enzyme", Arabian Journal of Chemistry, vol. 15, no. 4: Elsevier, pp. 103751, 2022. Abstract
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El-Deen, E. M. M., M. M. Anwar, A. A. Abd El-Gwaad, E. A. Karam, M. K. El-Ashrey, and R. R. Kassab, "Design and synthesis of some novel pyridothienopyrimidine derivatives and their biological evaluation as antimicrobial and anticancer agents targeting EGFR enzyme", Arabian Journal of Chemistry, vol. 15, no. 4: Elsevier, pp. 103751, 2022. Abstract
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Mohi El-Deen, E. M., M. M. Anwar, A. A. A. El-Gwaad, E. A. Karam, M. K. El-Ashrey, and R. R. Kassab, "Novel pyridothienopyrimidine derivatives: Design, synthesis and biological evaluation as antimicrobial and anticancer agents", Molecules, vol. 27, no. 3: MDPI, pp. 803, 2022. Abstract
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Mohi El-Deen, E. M., M. M. Anwar, A. A. A. El-Gwaad, E. A. Karam, M. K. El-Ashrey, and R. R. Kassab, "Novel pyridothienopyrimidine derivatives: Design, synthesis and biological evaluation as antimicrobial and anticancer agents", Molecules, vol. 27, no. 3: MDPI, pp. 803, 2022. Abstract
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El-Ashrey, M. K., R. O. Bakr, M. A. A. Fayed, R. H. Refaey, and Y. M. Nissan, "Pharmacophore based virtual screening for natural product database revealed possible inhibitors for SARS-COV-2 main protease", Virology, vol. 570: Academic Press, pp. 18–28, 2022. Abstract
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