Transplantation of Ex-Vivo Expanded Epithelial Stem Cells in Limbal Stem Cell Deficiency (Laboratory/Clinical Prospective Interventional Non- Controlled Nonrandomized Study)

Citation:
Lotfy, N. M. A., S. M. Sabry, H. M. A. Atta, and S. A. G. El-Din, Transplantation of Ex-Vivo Expanded Epithelial Stem Cells in Limbal Stem Cell Deficiency (Laboratory/Clinical Prospective Interventional Non- Controlled Nonrandomized Study), , Egypt, Cairo University, 2013.

Thesis Type:

PhD Thesis

Abstract:

Limbal stem-cell deficiency can be congenital or acquired; it can also be partial
or total. Treatment options include: conjunctival-limbal autografts, keratolimbal
lamellar allograft, and living-related conjunctival-limbal allografts. A novel
method of transplanting limbal stem cells is via ex-vivo expansion of limbal stem
cells; with the advantages of: a smaller limbal biopsy, reduced risk of precipitating
stem cell failure in the donor eye, and allowing the option of taking a further
biopsy if required.

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