Nystatin Production by a Local Streptmyces sp

Elattal, N. A, Hamdy, A. A, Ali, A. E, Amin, and M. A, "Nystatin Production by a Local Streptmyces sp", J. Pharm. Biomed. Sci., 2011.


Various soil samples were randomly collected at different places in south Delta, Egypt. A total of 105 Streptomyces isolates, were selected according to their morphological characteristics. Antifungal activity was assessed by agar well diffusion assay. Ten isolates showed antifungal activity against various reference strains of yeast and fungi. The maximum zone of inhibition was detected for Aspergillus niger and Candida albicans using cell homogenate of isolate N5. This potential isolate was identified on the bases of the International Streptomyces Project (ISP) as Streptomyces noursei. A?ccordingly the name Streptomyces noursei sp.N5 was proposed.