Assessment of Risk Factors for Fetal Congenital Anomalies Among Pregnant Women at El-Manial University Hospital

Marzouk, A. M. A., S. A. E. - K. Hassan, A. A. A. E. - Hamid, and H. M. Gaafar, Assessment of Risk Factors for Fetal Congenital Anomalies Among Pregnant Women at El-Manial University Hospital, , Egypt, Cairo University, 2012.

Thesis Type:

M.Sc Thesis


Background, congenital anomaly is a defect that is present at birth,
and can result from either genetic, environmental factors, or both. Aim, was to
assess the risk factors which may lead to fetal congenital anomalies. Design, a
descriptive research design was adopted. Sample, a total of 265 pregnant women
were recruited according to the following criteria: pregnant in a fetus with a
congenital anomaly; at any reproductive age; no specific gravidity or parity; single
or multiple gestations. Setting, Fetal Medicine Unit at El-Manial University
Hospital. Tools, two tools were constructed and filled in by the researcher: 1) fetal
assessment sheet 2) interviewing questionnaire schedule. Results, age range of the
pregnant women was 17-44 years with a mean of 26.63 ± 5.37 years. Seventeen
percent of them cannot read and write while, 20% had university education. Renal
anomalies, central nervous system (CNS), muscloskeletal , and cardiovascular
anomalies were the most common congenital anomalies constituted 36.6%, 34.7%,
20.8%, 10.6% respectively of the total anomalies. Regarding to risk factors for
congenital anomalies, 45.7% of the pregnant women had first degree
consanguinity, 16.6% had a family history of a congenital anomalies, 19.2% had a
previous child with a congenital anomalies, 29.1% gave a history of consuming
drugs during present pregnancy, 18.5% of the pregnant women live near industrial
source and 21.5% of them experienced infection during present pregnancy.
Conclusion, renal, CNS and muscloskeletal anomalies were the most common
type of congenital anomalies. Positive consanguinity, family history for congenital
anomalies, previous child with a congenital anomaly, consuming drugs during
pregnancy, living near industrial source and exposure to infections during
pregnancy, were the most common risk factors associated with congenital
anomalies. Recommendations, premarital examination for consanguineous
marriages should be encouraged. Antenatal care is very important for suspection
and early detection of congenital anomalies.

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