Alloimmunization and Erythrocyte Autoimmunization in Transfusion-Dependent Egyptian Thalassemic Patients

Citation:
DA, S., K. AM, B. E. RM, and M. SS., "Alloimmunization and Erythrocyte Autoimmunization in Transfusion-Dependent Egyptian Thalassemic Patients", J Pediatr Hematol Oncol, 2011.

Abstract:

Background: Alloimmunization to red blood cells' (RBCs) antigens and formation of autoantibodies against RBCs is a frequent complication among immunocompetent transfusion-dependent patients. Autoantibodies can result in clinical hemolysis and difficulty in cross-matching blood. The objective of this study was to evaluate the presence of alloantibodies and autoantibodies in regularly transfused ?-thalassemic patients and the factors influencing the development of alloantibodies.

Notes:

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