Publications

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2023
Mahrouse, M. A., Y. M. Youssef, and E. A. Mostafa, "Assessment of environmental impact of a novel stability-indicating RP-HPLC method and reported methods for the determination of selexipag in bulk and dosage form: A comparative study using different greenness assessment tools", Microchemical Journal, vol. 185, issue 108256, pp. 1-7, 2023.
Mahrouse, M. A., Y. M. Youssef, and E. A. Mostafa, "Plackett–Burman and face-centered composite designs for development and optimization of chromatographic method for the simultaneous determination of glycopyrronium, indacaterol and mometasone in their fixed dose combination inhaler – Green profile assessm", Journal of Pharmaceutical and Biomedical analysis, vol. 234, issue 115553, pp. 1-16, 2023. 2-_yasmine_experimental_design_hplc_green.pdf
2021
Moussa, B. A., M. A. Mahrouse, and M. G. Fawzy, "Application of experimental design in HPLC method optimization and robustness for the simultaneous determination of canagliflozin, empagliflozin, linagliptin, and metformin in tablet", Biomedical chromatography, vol. 35, issue 10, pp. 1-17, 2021.
Hassib, S. T., H. M. A. Hashem, M. A. Mahrouse, and E. A. Mostafa, "Development and Bio-Analytical Validation of Chromatographic Determination Method of Rufinamide in Presence of its Metabolite in Human Plasma", Journal of Chromatographic Science, pp. 1-7, 2021.
Mohammad, M. A. - A., M. A. Mahrouse, E. A. H. Amer, and N. S. Elharati, "Simultaneous determination of enalapril maleate and nitrendipine in tablets using spectrophotometric methods manipulating ratio spectra", Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, vol. 244, pp. 1-13, 2021.
Moussa, B. A., M. A. Mahrouse, and M. G. Fawzy, "Smart spectrophotometric methods for the simultaneous determination of newly co-formulated hypoglycemic drugs in binary mixtures", Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, vol. 257, pp. 119763, 2021. 4-_michael_spectro_2_ir.pdf
Moussa, B. A., H. M. A. Hashem, M. A. Mahrouse, and S. T. Mahmoud, "Synchronized determination of sacubitril and valsartan with some co-administered drugs in human plasma via UPLC-MS/MS method using solid phase extraction", Biomedical chromatography, vol. e5203, 2021.
Moussa, B. A., H. M. A. Hashem, M. A. Mahrouse, and S. T. Mahmoud, "Synchronized determination of the novel heart failure combination therapy containing sacubitril calcium and valsartan by a validated spectrofluorimetric method", Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, vol. 253, pp. 119613, 2021. 3-_sally_spectrofluorimetric_method.pdf
2020
Hassib, S. T., H. M. A. Hashem, M. A. Mahrouse, and E. A. Mostafa, "Determination of Rufinamide in the Presence of 1-[(2,6-Difluorophenyl)Methyl]-1H-1,2,3-Triazole-4 Carboxylic Acid Using RP-HPLC and Derivative Ratio Methods as Stability Indicating Assays to Be Applied on Dosage Form", Journal of AOAC INTERNATIONAL, vol. 103, issue 5, pp. 1215-1222, 2020.
Mahrouse, M. A., H. M. Elwy, and E. M. Salem, "Simultaneous determination of cefixime and erdosteine in combined dosage form using validated spectrophotometric methods", Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, vol. 241, pp. 1-10, 2020.
Mohammad, M. A. - A., M. A. Mahrouse, E. A. H. Amer, and N. S. Elharati2, "Validated LC–MS/MS method for the simultaneous determination of enalapril maleate, nitrendipine, hydrochlorothiazide, and their major metabolites in human plasma", Biomedical Chromatography, vol. e4955., pp. 1-11, 2020.
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2019
Moussa, B., M. A. Mahrouse, and M. G. Fawzy, "A validated LC-MS/MS method for simultaneous determination oflinagliptin and metformin in spiked human plasma coupled with solidphase extraction: Application to a pharmacokinetic study in healthyvolunteers", Journal of Pharmaceutical and Biomedical Analysis, vol. 163, pp. 153-161, 2019.
Mahrouse, M. A., and N. T. Lamei, "Experimental design methodology for optimization and robustness determination in ion pair RP-HPLC method development: Application for the simultaneous determination of metformin hydrochloride, alogliptin benzoate and repaglinide in tablets", Microchemical journal, vol. 147, pp. 691-706, 2019.
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El-Bagary, R. I., M. A. Mahrouse, M. M. El-Hakeem, A. B. Megally, and A. A. Mohamed, "Novel spectrophotometric methods for the determination of Leflunomide and Diacerein in binary mixtures", Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, vol. 220, pp. 117-121, 2019.
Mahrouse, M. A., A. A. El-Zaher, and A. M. ElGhany, "Validated Chromatographic Methods for Simultaneous Estimation of Cinnarizine in Binary Mixture with Paracetamol & Domperidone in Tablets", Current pharmaceutical analysis, vol. 15, pp. 429-438, 2019.
El-Zaher, A. A., M. A. Mahrouse, and A. M. ElGhany, "Validated Chromatographic Methods for The Simultaneous Estimation of Etamsylate and Mefenamic Acid in Presence of Their Main Impurities ", Current pharmaceutical analysis, vol. 15, pp. 624-631, 2019.
Moussa, B. A., H. M. A. Hashem, M. A. Mahrouse, and S. T. Mahmoud, "A validated RP‐HPLC method for the evaluation of the influence of grapefruit juice on liver S9 activation of sacubitril", Biomedical Chromatography, vol. e4553, pp. 1-8, 2019.
2018
Hassib, S. T., H. M. A. Hashem, M. A. Mahrouse, and E. A. Mostafa, "Determination of four antiepileptic drugs in plasma using ultra‐performance liquid chromatography with mass detection technique", Biomediacal chromatography, vol. 32, issue 8, pp. 1-9, 2018.
a Moussa, B., M. A. Mahrouse, and M. G. Fawzy, "Different resolution techniques for management of overlapped spectra: Application for the determination of novel co-formulated hypoglycemic drugs in their combined pharmaceutical dosage form", Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, vol. 205, pp. 235-242, 2018.
a Moussa, B., H. M. A. Hashem, M. A. Mahrouse, and S. T. Mahmoud, "Experimental Design Approach in HPLC Method Development: Application for the Simultaneous Determination of Sacubitril and Valsartan in Presence of Their Impurities and Investigation of Degradation Kineti", Chromatographia, vol. 81, issue 1, pp. 139-156, 2018. experimental_design.pdf
Hashem, H. M. A., and M. A. Mahrouse, "In vitro metabolism study of a novel P38 kinase inhibitor: in silico predictions, structure elucidation using MS/MS-I", Future Medicinal Chemistry, vol. 10, issue 2, pp. 201-220, 2018.
Hashem, H. M. A., and M. A. Mahrouse, "In vitro metabolism study of a novel P38 kinase inhibitor: in silico predictions, structure elucidation using MS/MS-I", Future medicinal chemistry, vol. 10, issue 2, pp. 201-220, 2018.
Hassib, S. T., M. A. Mahrouse, E. F. Elkady, and R. M. Sayed, "Simultaneous HPLC Determination of Betamethasone Esters-Containing Mixtures: Analysis of Their Topical Preparations", Journal of Chromatographic Science, vol. 56, issue 8, pp. 716-723, 2018.
Mahrouse, M. A., "Simultaneous ultraperformance liquid chromatography/tandem mass spectrometry determination of four antihypertensive drugs in human plasma using hydrophilic–lipophilic balanced reversed‐phase sorbents sample preparation protocol", Biomediacal chromatography, vol. 32, issue 12, pp. 1-10, 2018.
Lamei, N. T., and M. A. Mahrouse, "Smart spectrophotometric methods based on normalized spectra for simultaneous determination of alogliptin and metformin in their combined tablets", Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, vol. 204, pp. 743-747, 2018.
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