The role of contrast enema in the diagnosis and management of Hirschsprung’s disease; Comparative study between contrast enema findings and rectal biopsy in the diagnosis of Hirschsprung's Disease

Citation:
Marei M. The role of contrast enema in the diagnosis and management of Hirschsprung’s disease; Comparative study between contrast enema findings and rectal biopsy in the diagnosis of Hirschsprung's Disease. Abdelsattar AH, El-Saket H, El-Kotby M, editors. Cairo, Egypt: Cairo University; 2010. copy at http://scholar.cu.edu.eg/?q=mahmoud-marei/publications/role-contrast-enema-diagnosis-and-management-hirschsprung%E2%80%99s-disease-compa

Thesis Type:

MSc Thesis

Abstract:

AIM OF THE WORK

The aim of this work is to study the accuracy of contrast enema in the diagnosis of Hirschsprung's disease comparing it with the results of rectal biopsy which represents the gold standard.

SUMMARY AND CONCLUSION

The diagnosis of Hirschsprung’s disease presents a clinical challenge to the pediatric surgeon. Hirschsprung’s disease should be considered in any child who has a history of constipation dating back to the newborn period. In our study, the results of the contrast enema are well correlated and comparable to the rectal biopsy in the diagnosis of Hirschsprung’s disease. As barium enema is a noninvasive diagnostic tool, the presence of strongly positive enema findings associated with classic clinical presentation is considered in the author’s point of view sufficient evidence to operate. In cases of obistipant constipation and inconclusive contrast enema findings, thorough and careful medical management should be initially attempted, if failed; rectal biopsy by an experienced pediatric surgeon is indicated.

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