Feminizing genitoplasty in virilised females with congenital adrenal hyperplasia: Clinical aspects and surgical management

Citation:
Marei M. Feminizing genitoplasty in virilised females with congenital adrenal hyperplasia: Clinical aspects and surgical management. Abdelsattar AH, Hassan MM, Barbary MME, Elkotby M, editors. Egypt: Cairo University; 2013. copy at www.tinyurl.com/jcxe2tn

Thesis Type:

PhD Thesis

Abstract:

Congenital adrenal hyperplasia in females leads to virilization of the external genitalia and anomalous genitourinary tract. Surgical repair during infancy is indicated to raise a female child with external genitalia matching her gender and to avoid psychosocial and genitourinary complications. Earlier surgery is believed to be easier and of better results. The outcome parameters studied in this work are; (a) parents' and professionals' satisfaction of the appearance of the feminized external genitalia, (b) adequately sized and positioned vagina and urethra and (c) occurrence of short term complications. We propose a link between the two known theories by stipulating that although the confluence depth and operative difficulty occur in a spectrum rather than either "high" or "low"; this spectrum is concentrated in its middle third where the vagina joins the urethra near the point of pseudo-verumontanum.The degree of virilization does not accurately reflect the depth of the confluence or the operative difficulty.

Key Words: DSD, Intersex, Feminizing Genitoplasty, Urogenital Sinus, Virilization, Female Pseudohermaphrodite, Congenital Adrenal Hyperplasia.

03/2013, Degree: PhD Paediatric Surgery, Supervisors: Ayman H Abdelsattar, Mona Mamdouh Hassan, Mohamed M Elbarbary, Montasser M Elkotby

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