@article {246024, title = {Recent Advances in RPE Adenoma}, journal = {Egyptian Retina Journal}, volume = {10}, year = {2023}, pages = {1-6}, publisher = {Medknow}, abstract = {

Adenoma and adenocarcinoma, are two uncommon acquired true neoplasms of the RPE. They highly mimic uveal melanomas which carry high risk of metastasis so it is critical to recognize RPE tumors and distinguish them from melanomas.

The majority of RPE neoplasms present as a dome shaped elevated darkly pigmented lesion. The presence of exudative retinal detachment, yellow intraretinal exudation around the mass as well as the presence of a feeding artery and a draining vein are among the distinguishing features from uveal melanomas. Acquired RPE neoplasms are usually peripheral however, peripapillary RPE neoplasms has been reported.

Among the management options for the small sized RPE tumors below 4 mm in thickness are cryotherapy or transpupillary thermotherapy. For larger tumors; PDT, partial lamellar sclerouvectomy or external beam irradiation were recommended.

Recently, Episcleral Brachytherapy has been addressed to be an effective primary management plan with minimal long term complications in cases of RPE adenoma.

}, isbn = {2347-5617}, url = {https://journals.lww.com/ejrj/fulltext/2023/01000/recent_advances_in_rpe_adenoma.1.aspx}, author = {Swaify, Islam Y and Tamer A Macky and Shaymaa H Salah and Hamza, Hany S and Al-Etr, Salma Fekry and El Qadi, Layla} }