Khaled Mohamed
Professor of pharmaceutical organic chemistry
Al Kasr Eleieny street
(email)
Thiazolidinone Caspase-3 Fas-ligand Apoptosis Radiolabeling Technetium-99 m
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Mohamed, K. O., Y. M. Nissan, A. A. El-Malah, W. A. Ahmed, D. M. Ibrahim, T. M. Sakr, and M. A. Motaleb,
"
Design, synthesis and biological evaluation of some novel sulfonamide derivatives as apoptosis inducers
",
European Journal of medicinal chemistry
, vol. 135, issue -, pp. 424-433, Submitted.
european_j.med_.chem_2017.pdf
Publications
Bio
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4-thiadiazole; anticancer activity; structure-activity relationship; radiolabeling; in vivo pharmacokinetics
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: Z-configurated isomers; thiazole; hydrazinecarbothioamide; phenacylbromide; cytotoxicity; VEGFR-2; apoptosis; p53; mitochondrial membrane potential (MMP)
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benzotriazole; anticancer; imidazol-2-thione; antiproliferative activity; breast cancer; colchicine; tubulin
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Donepezil ● Acetylcholinesterase ● β-amyloid protein ● Gewald’s reaction ● Benzothiophene derivatives
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Halogenated chalcones; diaryl ether; pyrazoline; ROS; p38 MAPK; breast cancer; cell cycle profile
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Quinazolinone Thiazolidinone 3DQSAR pharmacophore Cytotoxic activity EGFR
(1)
Thiazolidinone Caspase-3 Fas-ligand Apoptosis Radiolabeling Technetium-99 m
(1)
Recent Publications
New 5-Aryl-1,3,4-Thiadiazole-Based Anticancer Agents: Design, Synthesis, In Vitro Biological Evaluation and In Vivo Radioactive Tracing Studies
Design, Synthesis and Cytotoxicity Screening of New Thiazole Derivatives as Potential Anticancer Agents through VEGFR-2 Inhibition
Development of new donepezil analogs: synthesis, biological screening and in silico study rational
Synthesis and biological evaluation of halogenated phenoxychalcones and their corresponding pyrazolines as cytotoxic agents in human breast cancer
Design, synthesis and biological evaluation of some novel sulfonamide derivatives as apoptosis inducers
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