Publications

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Submitted
Shabaan, M., K. O. Mohamed, Y. A. Elshaier, and A. Hammad, "Design and Synthesis of Pyrazolo[3,4-d]pyrimidinone Derivatives: Discovery of Selective Phosphodiesterase-5 Inhibitors.", Bioorganic & medicinal chemistry letters., vol. 101, issue 30, pp. 1-15, Submitted. paper_7_professor.pdf
Aziz, M. W., A. E. A. Gendy, K. O. Mohamed, and A. M. Kamal, "Design, synthesis and assessment of new series of quinazolinone derivatives as EGFR inhibitors along with their cytotoxic evaluation against MCF7 and A549 cancer cell lines", Bioorganic & medicinal chemistry letters., vol. 41, issue 127987, pp. 1-11, Submitted. bioorg_and_med_chem_letters_2021.pdf
Mohamed, K. O., Y. M. Nissan, A. A. El-Malah, W. A. Ahmed, D. M. Ibrahim, T. M. Sakr, and M. A. Motaleb, "Design, synthesis and biological evaluation of some novel sulfonamide derivatives as apoptosis inducers", European Journal of medicinal chemistry, vol. 135, issue -, pp. 424-433, Submitted. european_j.med_.chem_2017.pdf
Mohamed, K. O., T. Al-Warhi, M. Abualnaja, O. A. A. Ali, N. M. Alyamani, F. G. Elsaid, A. A. Shati, S. Albogami, E. Fayad, A. A. H. Almaaty, et al., "Design, Synthesis and Cytotoxicity Screening of New Thiazole Derivatives as Potential Anticancer Agents through VEGFR-2 Inhibition", Symmetry, vol. 14, issue 9, pp. 1-16, Submitted.
application/pdf iconsymmetry-islam_2022.pdf
Khayyat, A. N., K. O. Mohamed, A. M. Malebari, and A. El-Malah, "Design, Synthesis, and Antipoliferative Activities of Novel Substituted Imidazole-Thione Linked Benzotriazole Derivatives", molecules, vol. 26, issue 5983, pp. 1-17, Submitted. molecules-2021.pdf
Mohamed, K. O., L. W. Mohamed, Z. Mahmoud, and H. S. Sayed, "Development of new donepezil analogs: synthesis, biological screening and in silico study rational", MEDICINAL CHEMISTRY RESEARCH, vol. 31, issue 10, pp. 1754-1770, Submitted.
application/pdf iconmedicinal_chemistry_research_2022.pdf
Mohamed, K. O., R. M. El-Masry, B. M. Essa, A. A. Selim, S. Z. El-Emam, T. M. Sakr, H. H. Kadry, A. T. Taher, and S. M. Abou-Seri, "New 5-Aryl-1,3,4-Thiadiazole-Based Anticancer Agents: Design, Synthesis, In Vitro Biological Evaluation and In Vivo Radioactive Tracing Studies ", Pharmaceuticals, vol. 15, pp. 1-24, Submitted.
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Mohamed, K. O., P. A. Halim, R. A. Hassan, S. O. Hassanin, M. G. Khalil, A. M. Abdou, and E. O. Osman, "Synthesis and biological evaluation of halogenated phenoxychalcones and their corresponding pyrazolines as cytotoxic agents in human breast cancer", Journal of Enzyme Inhibition and Medicinal Chemistry, vol. 37, issue 1, pp. 189-201, Submitted.
application/pdf iconjournal_of_enzyme_inhibition__medicinal_chemistry__2022.pdf
Shabaan, M., A. M. Kamal, K. O. Mohamed, S. Faggal, and A. Elsahar, "Synthesis and biological evaluation of pyrazolone analogues as potential anti‐inflammatory agents targeting cyclooxygenases and 5‐lipoxygenase", Archiv der pharmazie, vol. 353 , issue 4, pp. 1-15, Submitted. paper-6_professor.pdf
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2025
Aziz, M. W., K. O. Mohamed, D. B. Farag, A. K. Khalifa, and Z. Mahmoud, "Effective scaffolds as antihypertensive agents, a long story with happy endings; a review tracing the promising reported candidates", Journal of Molecular Structure, vol. 1319, issue 2, pp. 1-38, 2025. journal_molecular_structure_2025.pdf
2024
Abdelhameid, M. K., E. Taher, M. Hara, M. Ramadan, and K. O. A. Mohamed, "Discovery of novel octahydroquinazoline scaffolds endowed with dual inhibition of tubulin polymerization/Eg5 against HCC: Apoptotic and radio-chemotherapeutic studies ", Bioorganic Chrmistry, vol. 148, pp. 1-18, 2024. bioorganic_chemistry_hara.pdf
Mohamed, K. O., A. A. Helwa, N. Reda, A. Elshewy, and K. Abdou, "Novel Pyrimidine-5-Carbonitriles as potential apoptotic and antiproliferative agents by dual inhibition of EGFRWT/T790M and PI3k enzymes; Design, Synthesis, biological Evaluation, and docking studies", bioorganic chemistry, vol. 145, pp. 1-21, 2024.
application/pdf iconbioorganic_chemistry_2024.pdf
Hara, M. A., K. O. Mohamed, M. Ramadan, M. K. Abdelhameid, and E. S. Taher, "Pyroptosis and chemical classifcation of pyroptotic agents", Molecular Diversity, vol. 28, issue 5, pp. 1-18, 2024.
Mohamed, K. O., N. S. M. Ibrahim, H. Kadry, and A. Zaher, "Review: synthesis and anticancer activity of pyrimido[4,5-b]quinolines in the last twenty years", chemical papers, vol. 78, issue 5, pp. 2695-2728, 2024.
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2023
Mohamed, K. O., A. A. Helwa, N. Reda, A. Elshewy, and H. Askary, "design, synthesis, and biological evaluation of new pyrimidine-5-carbonitrile derivatives as novel anticancer, dual EGFRWT/COX-2 inhibitors with docking studies", RSC advancs, vol. 13, pp. 32320-32296, 2023.
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Mohamed, K. O., A. Taher, A. Kasab, A. R. Mayhoub, M. M. Elsebaei, A. Elshewy, and I. G. Shahin, "New Phenylthiazoles: Design, Synthesis, and Biological Evaluation as Antibacterial, Antifungal,and Anti-COVID-19 Candidates", chemistry & biodiversity, vol. 20, issue 11, pp. 1-12, 2023.
application/octet-stream iconchemistry__biodiversity_2023.
Mohamed, K. O., L. W. Mohamed, H. S. Sayed, Z. Mahmoud, M. A. E. A. Fattah, and A. El-Malah, "New tetracyclic systems integrated thienopyridine scaffold as an anti-dementia lead: in silico study and biological screening", Medicinal Chemistry Research, vol. 32, issue 3, pp. 571-586, 2023.
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Mohamed, K. O., L. W. Mohamed, H. S. Sayed, and Z. Mahmoud, "Recent modifications of anti-dementia agents focusing on tacrine and/or donepezil analogs", Medicinal Chemistry , vol. 19, issue 4, pp. 311-324, 2023.
application/pdf iconmedicinal_chemistry_2022.pdf
Mohamed, K. O., N. S. M. Ibrahim, H. Kadry, and A. Zaher, "Synthesis of novel pyrimido[4,5-b]quinolines as potential anticancer agents and HER2 inhibitors", Chemical Biology & Drug Design, vol. 102, issue 5, pp. 996-1013, 2023.
application/pdf iconchemical_biology__drug_design_2023.pdf
Mohamed, K. O., N. S. M. Ibrahim, H. Kadry, and A. Zaher, "Synthesis of novel pyrimido[4,5‐b]quinoline derivatives as dual EGFR/HER2 inhibitors as anticancer agents", archive der pharmazie, vol. 357, issue 3, pp. 1-12, 2023.
application/pdf iconarchive_de_pharmaze_2023.pdf
2022
Shahin, I., K. O. Mohamed, A. Taher, A. R. Mayhoub, and A. Kassab, "The Anti-MRSA Activity of Phenylthiazoles: A Comprehensive Review", Current Pharmaceutical Design, vol. 28, issue 43, pp. 3469-3477, 2022.
application/pdf iconcurrent_pharmaceutical_design_2023.pdf
Al-Warhi, T., K. O. Mohamed, M. Abualnaja, O. A. A. Ali, N. M. Alyamani, F. G. Elsaid, A. A. Shati, S. Albogami, E. Fayad, A. A. H. Almaaty, et al., "Design, Synthesis and Cytotoxicity Screening of New Thiazole Derivatives as Potential Anticancer Agents through VEGFR-2 Inhibition", Symmetry, vol. 14, issue 9, pp. 1-16, 2022.
application/pdf iconsymmetry-islam_2022.pdf
2020
Shabaan, M., A. M. Kamal, K. O. Mohamed, S. Faggal, A. Elsahar, and N. Farag, "Design, synthesis, and biological evaluation of new pyrazoloquinazoline derivatives as dual COX‐2/5‐LOX inhibitors", Archiv der pharmazie, vol. 353 , issue 11, pp. 1-17, 2020.
Elhamied, M. K. A., K. O. Mohamed, I. Zaki, and M. Ramadan, "Design, Synthesis, and Cytotoxic Screening of Novel Azole. Derivatives on Hepatocellular Carcinoma (HepG2 Cells).", Bioorganic Chemistry, vol. 101, pp. 1-20, 2020. paper_8_professor.pdf
Mohamed, K. O., A. Taher, A. Kassab, I. Galal, and A. E. Mayehob, "Evaluation of N-phenyl-2-aminothiazoles for treatment of multi-drug resistant and intracellular Staphylococcus aureus infections", European Journal of medicinal chemistry, vol. 202, pp. 1-11, 2020. paper_of_antimicrobial_agents.pdf
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