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Salah, S., H. M. Lotfy, S. M. Sabry, A. E. Hamshary, and H. Taher, "Systemic lupus erythematosus in Egyptian children", Rheumatology international, vol. 29, no. 12: Springer-Verlag, pp. 1463–1468, 2009. Abstract
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Salah, S., samia rizk, hala lotfy, salma el houshy, huda marzouk, and yomna farag, "MEFV gene mutations in Egyptian children with Henoch-Schӧnlein purpura", Pediatr Rheumatol Online J. 2014, 12 :41 (9 September 2014), vol. 12, pp. 41, 2014. hsp_paper.pdf
Salah, S., H. M. Lotfy, S. M. Sabry, A. E. Hamshary, and H. Taher, "Systemic lupus erythematosus in Egyptian children", Rheumatology international, vol. 29, no. 12: Springer-Verlag, pp. 1463–1468, 2009. Abstract
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Salah, S., H. M. Lotfy, S. M. Sabry, A. E. Hamshary, and H. Taher, "Systemic lupus erythematosus in Egyptian children", Rheumatology international, vol. 29, no. 12: Springer-Verlag, pp. 1463–1468, 2009. Abstract
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Salah, S., M. El-Shabrawi, hala lotfy, hala Shiba, maha Abou-Zekri, and yomna farag, "Detection of Mediterranean fever gene mutations in Egyptian children with inflammatory bowel disease.", Int J Rheum Dis. , vol. [Epub ahead of print], issue 2014 Oct 8, 2014. ibd_final_copy.pdf
Salah, S., hala lotfy, abir nabil, and ahmed kaddah, "Damage index in childhood -onset systemic lupus erythematosus in Egypt ", Pediatr Rheumatol Online J. 2011 Dec 9;9(1):36. doi: 10.1186/1546-0096-9-36, vol. 1, issue 9, pp. 36, 2011. damage.pdf
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huda marzouk, H. M. Lotfy, yomna farag, L. A. Rashed, and K. El-Garf, "Mean platelet volume and splenomegaly as useful markers of subclinical activity in Egyptian children with familial Mediterranean fever: a cross-sectional study", International Journal of Chronic Diseases, vol. 2015: Hindawi, 2015. Abstract
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huda marzouk, H. M. Lotfy, yomna farag, L. A. Rashed, and K. El-Garf, "Mean platelet volume and splenomegaly as useful markers of subclinical activity in Egyptian children with familial Mediterranean fever: a cross-sectional study", International Journal of Chronic Diseases, vol. 2015: Hindawi, 2015. Abstract
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huda marzouk, H. M. Lotfy, yomna farag, L. A. Rashed, and K. El-Garf, "Mean platelet volume and splenomegaly as useful markers of subclinical activity in Egyptian children with familial Mediterranean fever: a cross-sectional study", International Journal of Chronic Diseases, vol. 2015: Hindawi, 2015. Abstract
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Mahmoud, S. S. - E. - D., H. M. Bazaraa, H. M. Lotfy, and D. M. Abd-El-Aziz, "Renal involvement in childhood-onset systemic lupus erythematosus in Egypt", Rheumatology international, vol. 32, no. 1: Springer-Verlag, pp. 47–51, 2012. Abstract
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Lotfy, H. M., E. F. Halawa, and M. E. Baz, "Pulmonary involvement in juvenile-onset systemic lupus erythematosus patients asymptomatic for respiratory disease", Egyptian Journal of Bronchology, vol. 9, no. 1: Springer, pp. 59–63, 2015. Abstract
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Lotfy, H. M., E. F. Halawa, and M. E. Baz, "Pulmonary involvement in juvenile-onset systemic lupus erythematosus patients asymptomatic for respiratory disease", Egyptian Journal of Bronchology, vol. 9, no. 1: Springer, pp. 59–63, 2015. Abstract
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Lotfy, H. M., H. S. M. El Dien, N. M. El Minawi, and H. A. W. A. Aziz, "The role of Doppler Ultrasonography in evaluating disease activity in a group of juvenile idiopathic arthritis patients", The Egyptian Journal of Radiology and Nuclear Medicine, vol. 49, no. 4: Elsevier, pp. 1036–1042, 2018. Abstract
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Lotfy, H. M., H. S. M. El Dien, N. M. El Minawi, and H. A. W. A. Aziz, "The role of Doppler Ultrasonography in evaluating disease activity in a group of juvenile idiopathic arthritis patients", The Egyptian Journal of Radiology and Nuclear Medicine, vol. 49, no. 4: Elsevier, pp. 1036–1042, 2018. Abstract
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Lotfy, H. M., S. M. Sabry, E. E. Ghobrial, S. A. Abed, and others, "The effect of regular hemodialysis on the nutritional status of children with end-stage renal disease", Saudi Journal of Kidney Diseases and Transplantation, vol. 26, no. 2: Medknow Publications, pp. 263, 2015. Abstract
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Lotfy, H. M., H. S. M. El Dien, N. M. El Minawi, and H. A. W. A. Aziz, "The role of Doppler Ultrasonography in evaluating disease activity in a group of juvenile idiopathic arthritis patients", The Egyptian Journal of Radiology and Nuclear Medicine, vol. 49, no. 4: Elsevier, pp. 1036–1042, 2018. Abstract
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Lotfy, H. M., E. F. Halawa, and M. E. Baz, "Pulmonary involvement in juvenile-onset systemic lupus erythematosus patients asymptomatic for respiratory disease", Egyptian Journal of Bronchology, vol. 9, no. 1: Springer, pp. 59–63, 2015. Abstract
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hala lotfy, manal Kandil, marriane Issac, S. Salah, nagwa Ismail, and A. mohamed Mawla, "MEFV mutations in egyptian children with systemic-onset juvenile idiopathic arthritis. Lotfy HM, Kandil ME, Issac MS, Salah S, Ismail NA, Abdel Mawla MA.", Mol Diagn Ther. , vol. 18 , issue (5), pp. 549-57., 2014. mefv_paper_online_form.pdf
Lotfy, H. M., S. M. Sabry, E. E. Ghobrial, S. A. Abed, and others, "The effect of regular hemodialysis on the nutritional status of children with end-stage renal disease", Saudi Journal of Kidney Diseases and Transplantation, vol. 26, no. 2: Medknow Publications, pp. 263, 2015. Abstract
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Eissa, M., Y. El Miedany, W. Hassan, D. Mekkawy, M. A. Mortada, S. I. Nasef, M. El Gaafary, hala lotfy, yomna farag, G. El Deriny, et al., AB0962 UPDATE FOR THE CLINICAL PRACTICE: INTEGRATED, EVIDENCE-BASED APPROACH FOR THE MANAGEMENT OF JUVENILE SPONDYLOARTHRITIS, : BMJ Publishing Group Ltd, 2019. Abstract
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Eissa, M., Y. El Miedany, W. Hassan, D. Mekkawy, M. A. Mortada, S. I. Nasef, M. El Gaafary, hala lotfy, yomna farag, G. El Deriny, et al., AB0962 UPDATE FOR THE CLINICAL PRACTICE: INTEGRATED, EVIDENCE-BASED APPROACH FOR THE MANAGEMENT OF JUVENILE SPONDYLOARTHRITIS, : BMJ Publishing Group Ltd, 2019. Abstract
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Eissa, M., Y. El Miedany, W. Hassan, D. Mekkawy, M. A. Mortada, S. I. Nasef, M. El Gaafary, hala lotfy, yomna farag, G. El Deriny, et al., AB0962 UPDATE FOR THE CLINICAL PRACTICE: INTEGRATED, EVIDENCE-BASED APPROACH FOR THE MANAGEMENT OF JUVENILE SPONDYLOARTHRITIS, : BMJ Publishing Group Ltd, 2019. Abstract
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Alkwai, H. M., A. Mirza, R. Abdwani, A. Asiri, R. Bakry, A. Alenazi, K. Khawaja, hala lotfy, M. Almutairi, M. Muzaffer, et al., "Consensus clinical approach for a newly diagnosed systemic juvenile idiopathic arthritis among members of the pediatric rheumatology Arab group.", International journal of pediatrics & adolescent medicine, vol. 8, issue 3, pp. 129-133, 2021. Abstract
application/pdf icon1-s2.0-s2352646721000508-main.pdf_consensus.pdf

BACKGROUND: Systemic juvenile idiopathic arthritis (sJIA) is a diagnosis of exclusion. The complex nature and clinical variety of the disease, as well as the vast clinical variation of disease presentation, may lead to difficulties in disease detection and subsequent delays in treatment.

AIM: To provide a consensus guidance on the management of newly diagnosed sJIA patients among pediatric rheumatologists in Arab countries.

METHODS: This work was conducted in two phases. The first phase utilized an electronic survey sent through an email invitation to all pediatric rheumatologists in Arab countries. In the second phase, a Task Force of ten expert pediatric rheumatologists from Arab countries met through a series of virtual meetings. Results obtained in phase one were prioritized using a nominal group and Delphi-like techniques in phase two.

RESULTS: Seven overarching principles and a set of recommendations were approved by the Task Force to form the final consensus.

CONCLUSION: This is the first consensus on a clinical approach for pediatric rheumatic diseases among Arab pediatric rheumatologists. It is presented as a guidance on the clinical approach to sJIA that requires further evidence, and future updates are anticipated.

Al-Mayouf, S. M., S. Hashad, K. Khawaja, A. Alrasheedi, R. Abdwani, A. Abushhaiwia, M. AlSuwaiti, R. Alzyoud, S. Al Abrawi, A. Asiri, et al., "Cumulative Damage in Juvenile Idiopathic Arthritis: A Multicenter Study From the Pediatric Rheumatology Arab Group", Arthritis Care & Research, vol. 73, no. 4, pp. 586–592, 2021. Abstract
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Al-Mayouf, S. M., M. Almutairi, K. Bouayed, S. Habjoka, D. Hadef, H. M. Lotfy, C. Scott, E. M. Sharif, and N. Tahoun, "Epidemiology and demographics of juvenile idiopathic arthritis in Africa and Middle East.", Pediatric rheumatology online journal, vol. 19, issue 1, pp. 166, 2021. Abstract
application/pdf icon12969_2021_article_650.pdf_epidemiology.pdf

Juvenile Idiopathic Arthritis (JIA) is a group of chronic heterogenous disorders that manifests as joint inflammation in patients aged <16 years. Globally, approximately 3 million children and young adults are suffering from JIA with prevalence rates consistently higher in girls. The region of Africa and Middle East constitute a diverse group of ethnicities, socioeconomic conditions, and climates which influence the prevalence of JIA. There are only a few studies published on epidemiology of JIA in the region. There is an evident paucity of adequate and latest data from the region. This review summarizes the available data on the prevalence of JIA and its subtypes in Africa and Middle East and discusses unmet needs for patients in this region. A total of 8 journal publications were identified concerning epidemiology and 42 articles describing JIA subtypes from Africa and Middle East were included. The prevalence of JIA in Africa and Middle East was observed to be towards the lower range of the global estimate. We observed that the most prevalent subtype in the region was oligoarticular arthritis. The incidence of uveitis and anti-nuclear antibody (ANA) positivity were found to be lower as compared to the incidence from other regions. There is a huge unmet medical need in the region for reliable epidemiological data, disease awareness, having regional and local treatment guidelines and timely diagnosis. Paucity of the pediatric rheumatologists and economic disparities also contribute to the challenges regarding the management of JIA.

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