Publications

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2024
Abdelaziz, M., A. F. Mohamed, H. F. Zaki, and S. S. Gad, "Agomelatine improves memory and learning impairments in a rat model of LPS-induced neurotoxicity by modulating the ERK/SorLA/BDNF/TrkB pathway", Naunyn Schmiedebergs Archives of Pharmacology. , vol. 397(3), pp. 1701-1714., 2024. agomelatine_autophagy.pdf
Mohamed, S. S., H. F. Zaki, and S. N. Raafat, "The Effect of Clopidogrel and Ticagrelor on Human Adipose Mesenchymal Stem Cell Osteogenic Differentiation Potential: In Vitro Comparative Study", Advances in Pharmacological and Pharmaceutical Sciences, vol. 2024, pp. 2990670, 2024. ticagrelor_clopidogrel_on_osteogenic_differentiation.pdf
Shalaby, N., H. F. Zaki, O. A. Badary, S. Kamal, M. Nagy, D. Makhlouf, A. Elnashar, E. E. Nady, S. A. Abdelshafi, S. Abouelnaga, et al., "Efficacy and Toxicity of Vincristine and CYP3A5 Genetic Polymorphism in Rhabdomyosarcoma Pediatric Egyptian Patients", Asian Pacific Journal of Cancer Prevention, vol. 25(4), pp. 1391-1409, 2024. vincristine_rhabdomyosarcoma.pdf
El-Kadi, R. A., N. F. Abdelkader, H. F. Zaki, and A. S. Kamel, "Influence of β-catenin signaling on neurogenesis in neuropsychiatric disorders: Anxiety and depression", Drug Development Research, vol. 85(1), pp. e22157., 2024. anxiety_and_depression_review.pdf
Mustafa, A. M., A. M. Shaheen, H. F. Zaki, and M. A. Rabie, "Nicorandil and carvedilol mitigates motor deficits in experimental autoimmune encephalomyelitis-induced multiple sclerosis: Role of TLR4/TRAF6/MAPK/NF-κB signalling cascade", International Immunopharmacology, vol. 127, pp. 111387, 2024. nicorcandil_ms.pdf
2023
El-Sayed, R. M., A. M. Abd ElAziz, H. F. Zaki, and N. A. O. Rasheed, "Cilostazol novel neuroprotective mechanism against rotenone-induced Parkinson's disease in rats: Correlation between Nrf2 and HMGB1/TLR4/PI3K/Akt/mTOR signaling", International Immunopharmacology, vol. 117, pp. 109986, 2023. cilastazole_in_rotenene_lesioned_rats-main.pdf
Elhefnawy, E. A., H. F. Zaki, N. E. N. Maraghy, K. A. Ahmed, and E. A. A. El-Haleim, "Genistein and/or sulfasalazine ameliorate acetic acid-induced ulcerative colitis in rats via modulating INF-γ/JAK1/STAT1/IRF-1, TLR-4/NF-κB/IL-6, and JAK2/STAT3/COX-2 crosstalk", Biochemical Pharmacology, vol. 214, pp. 115673, 2023. genistein_uc-main.pdf
Mohamed, A. F., H. M. Sayed, H. F. Zaki, and M. M. Safar, "Modulation of TLR4/NF- Modulation of TLR4/NF-κB, Nrf2/HO-1 and PI3K/Akt signaling by cilostazol mitigates lipopolysaccharide-induced septic acute kidney injury", Bulletin of Faculty of Pharmacy Cairo University, vol. 60, pp. 1-11, 2023.
application/pdf iconcilastazol_kidney_lps_sepsis.pdf
El-Sayed, R. M., M. N. Fawzy, H. F. Zaki, and E. A. A. El-Haleim, "Neuroprotection impact of biochanin A against pentylenetetrazol-kindled mice: Targeting NLRP3 inflammasome/TXNIP pathway and autophagy modulation", International Immunopharmacology, vol. 115, pp. 109711, 2023. biochanin_a_final.pdf
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Adel, N., R. Khedr, M. El anany, H. F. Zaki, H. Hafez, and H. El-Abhar, "Outcome and Safety of Colistin Usage in Pediatric Cancer Patients with Carbapenem Resistant Enterobacteriaceae Bacteremia at Children Cancer Hospital Egypt", Annals of African Medicine, vol. 22(1), pp. 82-87, 2023. colistin.pdf
2022
Shalaby, H. N., H. F. Zaki, A. A. A. Ain‑Shoka, and R. A. Mohammed, "Adenosine A2A Receptor Blockade Ameliorates Mania Like Symptoms in Rats: Signaling to PKC‑α and Akt/GSK‑3β/β‑Catenin", Molecular Neurobiology, vol. 59, pp. 6397–6410, 2022. adenosine_final.pdf
Azar, Y. O., G. A. Badawi, H. F. Zaki, and S. M. Ibrahim, "Agmatine-mediated inhibition of NMDA receptor expressionand amelioration of dyskinesia via activation of Nrf2 andsuppression of HMGB1/RAGE/TLR4/MYD88/NF-κB signalingcascade in rotenone lesioned rats", Life Sciences, vol. 311, pp. 121049, 2022.
application/pdf iconagomelatine_final.pdf
Shafey, G. M., E. R. Rashed, H. F. Zaki, A. S. Attia, and M. A. El-Ghazaly, "Molecular mechanisms involved in the effects of morin in experimental hepatic encephalopathy", Biofactors, vol. 48, pp. 1166–1178., 2022. morin_paper_final.pdf
Khalifa, M., R. M. Abdelsalam, M. M. Safar, and H. F. Zaki, "Phosphodiesterase (PDE) III inhibitor, Cilostazol, improved memory impairment in aluminum chloride-treated rats: modulation of cAMP/CREB pathway", Infammopharmacology, vol. 30, pp. 2477–2488, 2022.
application/pdf iconphosphodiesterase_pde_iii_inhibitor_cilostazol_imp.pdf
Monir, N., M. M. Saber, A. S. Awad, M. E. Elsherbiny, and H. F. Zaki, "Repression of inflammatory pathways with Boswellia for alleviation of liver injury after renal ischemia reperfusion ", Life Sciences, vol. 306, pp. 120799, 2022. bosweillia_final.pdf
Nawwar, D. A., H. F. Zaki, and R. H. Sayed, "Role of the NRG1/ErbB4 and PI3K/AKT/mTOR signaling pathways in the anti‑psychotic efects of aripiprazole and sertindole in ketamine‑induced schizophrenia‑like behaviors in rats", Infammopharmacology, vol. 30, pp. 1891–1907, 2022. ketamine_final.pdf
Saber, M. M., N. Monir, A. S. Awad, M. E. Elsherbiny, and H. F. Zaki, "TLR9: A friend or a foe", Life Sciences, vol. 307, pp. 120874, 2022. tlr-9_review.pdf
2021
Karam, H., E. Shaaban, A. Fahmy, H. Zaki, and S. Kenawy, "Improvement of Naja haje snake antivenom production using gamma radiation and a biotechnological technique", Toxin Reviews, vol. 40, issue 1, pp. 48-58, 2021. improvement_of_naja_haje_snake_antivenom_production_using_gamma_radiation_and_a_biotechnological_technique.pdf
Mustafa, A. M., M. A. Rabie, H. F. Zaki, and A. M. Shaheen, "Inhibition of Brain GTP Cyclohydrolase I Attenuates 3-Nitropropionic Acid-Induced Striatal Toxicity: Involvement of Mas Receptor/PI3k/Akt/CREB/ BDNF Axis", Frontiers in Pharmacology, vol. 12, pp. 740966, 2021.
application/pdf icon24-diamino-6-hydroxypyrimidine_in_huntingtons_disease.pdf
Salem, M. A., R. S. Ismail, H. F. Zaki, H. M. M. Arafa, and A. S. N. El-Khatib, "L-carnitine extenuates endocrine disruption, inflammatory burst and oxidative stress in carbendazim-challenged male rats via upregulation of testicular StAR and FABP9, and downregulation of P38-MAPK pathways", Toxicology, vol. 457, pp. 152808, 2021. carnitine_testicular_protection.pdf
Badawi, G. A., M. M. Shokr, H. F. Zaki, and A. F. Mohamed, "Pentoxifylline prevents epileptic seizure via modulating HMGB1/RAGE/TLR4 signalling pathway and improves memory in pentylenetetrazol kindling rats", Clinical and Experimental Pharmacology and Physiology. , vol. 48, issue 8, pp. 1111–1124, 2021. pentoxyfilline_final.pdf
Mansour, S. M., S. Aly, S. H. M. Hassan, and H. F. Zaki, "Protective effect of sitagliptin and whole-body c-irradiation in diabetes-induced cardiac injury", Canadian Journal of Physiology and Pharmacology, vol. 99, pp. 676–684, 2021.
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Fouad, M. R., R. M. Salama, H. F. Zaki, and A. E. El-Sahar, "Vildagliptin attenuates acetic acid-induced colitis in rats via targeting PI3K/Akt/NFκB, Nrf2 and CREB signaling pathways and the expression of lncRNA IFNG-AS1 and miR-146a", International Immunopharmacology, vol. 92, pp. 107354, 2021. vildagliptine_colitis_final.pdf
Emam, A. M., M. Asaad, N. A. Ahmed, and H. F. Zaki, "Vortioxetine mitigates neuronal damage by restricting PERK/eIF2α/ATF4/CHOP signaling pathway in rats subjected to focal cerebral ischemia-reperfusion", Life Sciences, vol. 283, pp. 119865, 2021. vortioxetine_paper.pdf
2020
El-Khatib, Y. A., R. H. Sayed, N. A. Sallam, H. F. Zaki, and M. M. Khattab, "17β-Estradiol augments the neuroprotective effect of agomelatine in depressive- and anxiety-like behaviors in ovariectomized rats", Psychopharmacology, vol. 237, pp. 2873–2886, 2020. agomelatine_final.pdf