Glucose homeostasis in chloroquine-treated normal rats

Gaafar×, K., "Glucose homeostasis in chloroquine-treated normal rats", journal of the egyptian german society of zoology, vol. 14 (A), pp. 177-189, 1994.


Glucose tolerance (GT), peripheral insulin activity (A) and beta cell function (CIR) were improved on prolonged chloroquine administration to normal male rats, while the acute effects comprised hyperinsulinaemia with unaltered blood glucose levels. This study explains some of the seemingly conflicting results due to chloroquine treatment and concludes that the drug is not damaging to glucose homeostasis in long term treatment.

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