Publications

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2024
Abdalhameid, E., R. M. Abdelsalam, E. A. A. El‑Haleim, G. S. Georgy1, H. M. Fawzy, and S. A. Kenawy, "Cinnamic acid mitigates methotrexate-induced lung fibrosis in rats: comparative study with pirfenidone", Naunyn-Schmiedeberg's Archives of Pharmacology, vol. 397, pp. 1071-1079, 2024.
Abdel-Kareem, N. M., S. M. Elshazly, M. Galal, A. A. Aldahish, S. A. Zaitone, S. K. Ali, and E. A. A. El-Haleim, "Nifedipine Improves the Ketogenic Diet Effect on Insulin-Resistance-Induced Cognitive Dysfunction in Rats", pharmaceuticals, vol. 17, issue 8, pp. 1054, 2024.
Shendy, H. M., S. S. Mohamed, E. A. A. El-Haleim, O. Galal, W. Wadie, A. Helal, and M. T. Khayyal, "Rice bran extract mitigates depressive-like behavior in dextran sulfate sodium-induced colitis: Involvement of the gut-brain axis and Sirt1 signaling pathway", Food and Chemical Toxicology, vol. 184, pp. 114386, 2024.
2023
Abdel-Kareem, N. M., S. M. Elshazly, M. Galal, and E. A. A. El-Haleim, "Challenges and Opportunities in Insulin Resistance-induced Cognitive Dysfunction", BULLETIN OF FACULTY OF PHARMACY, CAIRO UNIVERSITY, vol. 61, issue 1, pp. 46-56, 2023.
Elhefnawy, E. A., H. F. Zaki, N. E. N. Maraghy, K. A. Ahmed, and E. A. A. El-Haleim, "Genistein and/or sulfasalazine ameliorate acetic acid-induced ulcerative colitis in rats via modulating INF-γ/JAK1/STAT1/IRF-1, TLR-4/NF-κB/IL-6, and JAK2/STAT3/COX-2 crosstalk", Biochemical Pharmacology, vol. 214, pp. 115673, 2023.
El-Sayed, R. M., M. N. Fawzy, H. F. Zaki, and E. A. A. El-Haleim, "Neuroprotection impact of biochanin A against pentylenetetrazol-kindled mice: Targeting NLRP3 inflammasome/TXNIP pathway and autophagy modulation", International Immunopharmacology, vol. 115, pp. 109711, 2023.
Wadie, W., S. S. Mohamed, E. A. A. El-Haleim, and M. T. Khayyal, "Niacin modulates depressive-like behavior in experimental colitis through GPR109A-dependent mechanisms", Life Sciences, vol. 230, pp. 122004, 2023.
2022
Didamoony, M. A., A. M. Atwa, E. A. A. El-Haleim, and L. A. Ahmed, "Bromelain ameliorates D-galactosamine-induced acute liver injury: role of SIRT1/LKB1/AMPK, GSK3β/Nrf2 and NF-κB p65/TNF-α/caspase-8, -9 signalling pathways", Journal of Pharmacy and Pharmacology, vol. 74, pp. 1765-1775, 2022.
El-Haleim, E. A. A., and N. A. Sallam, "Vitamin D modulates hepatic microRNAs and mitigates tamoxifen-induced steatohepatitis in female rats", Fundamental and clinical pharmacology, vol. 36, pp. 338–349, 2022.
application/pdf iconvitamin_d_modulates_hepatic_micrornas_and_mitigates.pdf
2021
Ahmed, L. A., A. F. Mohamed, E. A. A. El-Haleim, and D. M. El-Tanbouly, "Boosting Akt Pathway by Rupatadine Modulates Th17/Tregs Balance for Attenuation of Isoproterenol- Induced Heart Failure in Rats", Frontiers in Pharmacology, vol. 12, 2021.
application/pdf iconboosting_akt_pathway_by_rupatadine_modulates_th17-tregs_balance_for_attenuation_of_isoproterenol-induced_heart_failure_in_rats.pdf
2020
El-Shiekh, R. A., R. M. Ashour, E. A. A. El-Haleim, K. A. Ahmed, and E. Abdel-Sattar, "Hibiscus sabdariffa L.: A potent natural neuroprotective agent for the prevention of streptozotocin-induced Alzheimer’s disease in mice", Biomedicine & Pharmacotherapy, vol. 128, 2020.
application/pdf iconhibiscus_sabdariffa_l._a_potent_natural_neuroprotective_agent_for_the.pdf
El-Haleim, E. A. A., "Molecular Study on the Potential Protective Effects of Bee Venom against Fructose-Induced Nonalcoholic Steatohepatitis in Rats", Pharmacology, vol. 105, issue (11-12), pp. 692–704, 2020.
application/pdf iconmolecular_study_on_the_potential_protective.pdf
2019
Khayyal, M. T., W. Wadie, E. A. A. El-Haleim, K. A. Ahmed, O. Kelber, R. M. Ammar, and H. Abdel-Aziz, "STW 5 is effective against nonsteroidal anti-inflammatory drugs induced gastro-duodenal lesions in rats.", World Journal of Gastroenterology, vol. 25, issue 39, pp. 5926-5935, 2019.
2016
EA, A. E. - H., B. AK, and S. S, "Effects of combined PPAR-γ and PPAR-α agonist therapy on fructose induced NASH in rats: Modulation of gene expression", Eur J Pharmacol, vol. 773, pp. 59-70, 2016. eur_j_ph.pdf
EA, A. E. - H., B. AK, and S. S, "Resveratrol and fenofibrate ameliorate fructose-induced NASH by modulation of genes expression", World J Gastroenterol, vol. 22, issue 10, pp. 2869-3068, 2016. wjg.pdf
2015
EA, A. E. - H., B. AK, and S. S, "Resveratrol and fenofibrate ameliorate fructose-induced NASH in rats by modulation of liver and adipose tissue expression of genes", The 12th Congress of the EACPT, Madrid, Spain, Madrid, Spain, 2015. EACPT Conference Abstract.pdf
EA, A. E. - H., B. AK, and S. S, "Resveratrol effect on fructose-induced NASH: a mechanistic approach", Inter J Dev Res, vol. 5, issue 09, pp. 5532–5541, 2015. int_j_dev_res.pdf
2010
EA, A. E. - H., E. - S. NS, and K. SA, "Neuroprotective Effect of Thyme and Ginger Extracts on Scopolamine-Induced Dementia in Rats", 2nd Scientific Conference of Faculty of Pharmacy, Cairo University "Quality Assurance in Pharmacy Education", Cairo Unniversity, 2010. Quality Assurance in Pharmacy Educationan Conference Abstract.doc