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Journal Article
Thomas J Vogl, Parvis Farshid, N. N. S. Z. B. B. N., and M. B. N. - E. N. - E. 1 A. Jijo Paul, Emannuel C. Mbalisike, "Ablation therapy of hepatocellular carcinoma: a comparative study between radiofrequency and microwave ablation", Abdominal Imaging, vol. 40, issue January, pp. 1829-1837, 2015. ablation_therapy_of_hepatocellular_carcinoma_a_comparative_study_between_radiofrequency_and_microwave_ablation.pdf
Nour-Eldin, N. - E. A., S. Exner, M. Al-Subhi, N. N. N. Naguib, B. Kaltenbach, A. Roman, and T. J. Vogl, "Ablation therapy of non-colorectal cancer lung metastases: retrospective analysis of tumour response post-laser-induced interstitial thermotherapy (LITT), radiofrequency ablation (RFA) and microwave ablation (MWA).", International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group, vol. 33, issue 7, pp. 820-829, 2017 11. Abstract

PURPOSE: To retrospectively compare the local tumour response and survival rates in patients with non-colorectal cancer lung metastases post-ablation therapy using laser-induced thermotherapy (LITT), radiofrequency ablation (RFA) and microwave ablation (MWA).

MATERIAL AND METHODS: Retrospective analysis of 175 computed tomography (CT)-guided ablation sessions performed on 109 patients (43 males and 66 females, mean age: 56.6 years). Seventeen patients with 22 lesions underwent LITT treatment (tumour size: 1.2-4.8 cm), 29 patients with 49 lesions underwent RFA (tumour size: 0.8-4.5 cm) and 63 patients with 104 lesions underwent MWA treatment (tumour size: 0.6-5 cm). CT scans were performed 24-h post-therapy and on follow-up at 3, 6, 12, 18 and 24 months.

RESULTS: The overall-survival rates at 1-, 2-, 3- and 4-year were 93.8, 56.3, 50.0 and 31.3% for patients treated with LITT; 81.5, 50.0, 45.5 and 24.2% for patients treated with RFA and 97.6, 79.9, 62.3 and 45.4% for patients treated with MWA, respectively. The mean survival time was 34.14 months for MWA, 34.79 months for RFA and 35.32 months for LITT. In paired comparison, a significant difference could be detected between MWA versus RFA (p = 0.032). The progression-free survival showed a median of 23.49 ± 0.62 months for MWA,19.88 ± 2.17 months for LITT and 16.66 ± 0.66 months for RFA (p = 0.048). The lowest recurrence rate was detected in lesions ablated with MWA (7.7%; 8 of 104 lesions) followed by RFA (20.4%; 10 of 49 lesions) and LITT (27.3%; 6 of 22 lesions) p value of 0.012. Pneumothorax was detected in 22.16% of MWA ablations, 22.73% of LITT ablations and 14.23% of RFA ablations.

CONCLUSION: LITT, RFA and MWA may provide an effective therapeutic option for non-colorectal cancer lung metastases with an advantage for MWA regarding local tumour control and progression-free survival rate.

Boris Bodelle, Martin Beeres, S. S. J. W. N. - E. A. N. - E. T. V. L. J., and B. S., "Automated Tube Potential Selection as a Method of Dose Reduction for CT of the Neck: First Clinical Results", American Journal of Roentgenology, vol. 204, issue April, pp. 1049–1054, 2015. automated_tube_potential.pdf
Jan-Erik Scholtz, Julian L. Wichmann, K. H. €users M. B. N. - E. A. N. - E., and T. L. Claudia Frellesen, Thomas J. Vogl, "Automated Tube Voltage Adaptation in Combination with Advanced Modeled Iterative Reconstruction in Thoracoabdominal Third-Generation 192-Slice Dual-Source Computed Tomography: Effects on Image Quality and Radiation Dose", Academic Radiology, vol. 22, pp. 1081–1087, 2015. automated_tube_voltage_adaptation_2015.pdf
Gruber-Rouh, T., A. Thalhammer, T. Klingebiel, N. - E. A. Nour-Eldin, T. J. Vogl, K. Eichler, N. Naguib, and M. Beeres, "Computed tomography-guided biopsies in children: accuracy, efficiency and dose usage", Italian Journal of Pediatrics, pp. 43-44, 2017.
Beeres M, Wichmann JL, P. M. E. V. T. J. N. - E. N. E. J. E. M., "CT chest and gantry rotation time: does the rotation time influence image quality?", Acta Radiologica, vol. 56, issue 8, pp. 950–954, 2015. ct_chest_and_gantry_rotation_time_does_the_rotation_time_influence_image_quality.pdf
Nour-Eldin, N. - E. A., M. Alsubhi, T. Gruber-Rouh, T. J. Vogl, B. Kaltenbach, H. H. Soliman, W. E. Hassan, S. M. Abolyazid, and N. N. Naguib, "CT-Guided Drainage of Pericardial Effusion after Open Cardiac Surgery.", Cardiovascular and interventional radiology, vol. 40, issue 8, pp. 1223-1228, 2017 Aug. Abstract

PURPOSE: This study was designed to evaluate the safety and efficacy of CT-guided drainage of the pericardial effusion in patients after cardiac surgery.

MATERIALS AND METHODS: The study included 128 consecutive patients (82 males, 46 females; mean age 66.6 years, SD: 4.2) complicated by pericardial effusion or hemopericardium after cardiac surgeries between June 2008 and June 2016. The medical indication for therapeutic pericardiocentesis in all patients was hemodynamic instability caused by pericardial effusion. The treatment criteria for intervention were evidence of pericardial tamponade with ejection fraction (EF) <50%. The preintervention ejection fraction was determined echocardiographically with value between 30 and 40%. Exclusion criteria for drainage were hemodynamically unstable patients or impaired coagulation profile (INR <1.8 or platelet count <75,000). Drains (8F-10F) were applied using Seldinger's technique under CT guidance.

RESULTS: Pericardiocentesis and placement of a percutaneous pericardial drain was technically successful in all patients. The mean volume of evacuated pericardial effusion was 260 ml (range 80-900 ml; standard deviation [SD]: ±70). Directly after pericardiocentesis, there was a significant improvement of the ejection fraction to 40-55% (mean: 45%; SD: ±5; p < 0.05). The mean percentage increase of the EF following pericardial effusion drainage was 10%. The drainage was applied anteriorly (preventricular) in 39 of 128 (30.5%), retroventricularly in 33 of 128 (25.8%), and infracardiac in 56 of 128 (43.8%). Recurrence rate of pericardial effusion after removal of drains was 4.7% (67/128). Complete drainage was achieved in retroventricular and infracardiac positioning of the catheter (p < 0.05) in comparison to the preventricular position of the catheter. Recorded complications included minimal asymptomatic pneumothorax and pneumomediastinum 2.3% (3/128) and sinus tachycardia 3.9% (5/128).

CONCLUSION: CT-guided drainage of postoperative pericardial effusion is a minimally invasive technique for the release of the tamponade effect of the effusion and improvement of cardiac output.

Gruber-Rouh, T., N. N. N. Naguib, M. Beeres, P. Kleine, T. J. Vogl, V. Jacobi, M. Alsubhi, and N. A. Nour-Eldin, "CT-guided hook-wire localisation prior to video-assisted thoracoscopic surgery of pulmonary lesions.", Clinical radiology, vol. 72, issue 10, pp. 898.e7-898.e11, 2017 Oct. Abstract

AIM: To assess the feasibility, safety, and efficacy of computed tomography (CT)-guided pulmonary nodule localisation using a hooked guide wire before video-assisted thoracoscopic surgery (VATS).

MATERIALS AND METHODS: The study included 79 patients with a history of malignancies outside the lung associated with pulmonary nodules. Mean lesion size was 0.7 cm (range 0.5-1.8 cm) and the mean lesion distance to the pleural surface was 1.5 cm (range 0.2-5 cm). All lesions (n=82) were marked with a 22-G hook wire. The technique was designed to insert the tip of the hook wire within or maximally 1 cm from the edge of the lesion. The Mann-Whitney U-test was used for univariate analyses and Fisher's exact test for categorical values.

RESULTS: The hooked guide wire was positioned successfully in all 82 pulmonary nodules within mean time of 9 minutes (8-20 minutes, SD: 2.5 minutes). The procedure time was inversely proportional to the size of the lesion (Spearman correlation factor 0.7). Minimal pneumothoraces were observed in five patients (7.6%). Pneumothorax was not correlated to the histopathology of the pulmonary nodules (p>0.09). Focal perilesional pulmonary haemorrhage developed in four patients (5%). Both haemorrhage and pneumothorax were significantly correlated to lesions <10 mm (p=0.02 and 0.01 respectively). The volume of resected lung tissue was significantly correlated to lesions of increased distance from the pleural surface ≥2.5 cm in comparison to lesions of <2.5 cm from the pleural surface.

CONCLUSION: CT-guided pulmonary nodule localisation prior to VATS could enable safe, accurate surgical guidance for the localisation of small pulmonary nodules.

T, G. - R., M. C, T. A, N. - E. NE, and L. M, "Current strategies in interventional oncology of colorectal liver metastases.", BRITISH JOURNAL OF RADIOLOGY, vol. 89(, pp. 1064, 2016.
M, B., W. JL, F. C, A. M, and N. - E. NE, "ECG-gated Versus Non-ECG-gated High-pitch Dual-source CT for Whole Body CT Angiography (CTA).", ACADEMIC RADIOLOGY, vol. Feb;23, issue (2), pp. 163-7, 2016.
J, P., C. A, S. P, V. TJ, and N. - E. NA, "Effect of diagnostic cone-beam computed tomography protocols on image quality, patient dose, and lesion detection", European Journal of Medical Physics, vol. 32, issue 12, pp. 1575-1583, 2016.
M, B., T. J, F. C, N. - E. NE, S. JE, H. E, and V. TJ, "Evaluation of different keV-settings in dual-energy CT angiography of the aorta using advanced image-based virtual monoenergetic imaging", INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING, vol. Jan;32, issue (1), pp. 137-44, 2016.
TJ, V., N. - E. NE, N. NN, Lehnert T, Ackermann H, H. R, and H. M, "Feasibility of assessing pulmonary blood volume using C-arm CT during transpulmonary chemoperfusion and chemoembolization in primary and secondary lung tumours", BRITISH JOURNAL OF RADIOLOGY, vol. Jun;89, pp. 1062, 2016.
Martin Beeres, Kimberly Williams, R. B. J. S. M. K. T. G. - R. W., C. F. N. - E. N. - E. T. V. A. J. Clara Lee, Julian L. Wichmann, and B. B. and Josef Matthias Kerl, "First Clinical Evaluation of High-Pitch Dual-Source Computed Tomographic Angiography Comparing Automated Tube Potential Selection With Automated Tube CurrentModulation", Journal Computer Assisted Tomography, vol. 39, pp. 624–628, 2015. first_clinical_evaluation_of_high-pitch_dual-source_computed.pdf
TJ, V., H. A, N. - E. NA, G. - R. T, E. K, Ackermann H, Bechstein WO, and N. NN, "High-frequency versus low-frequency microwave ablation in malignant liver tumours: evaluation of local tumour control and survival", INTERNATIONAL JOURNAL OF HYPERTHERMIA, vol. Dec;32, issue 8, pp. 868-875, 2016.
M, B., B. AM, W. JL, F. C, S. JE, A. M, B. B, and N. - E. NE, "Improved visual delineation of the intimal flap in Stanford type A and B dissections at 3rd generation dual-source high-pitch CT angiography.", Radiologia Medica, vol. Jul;121, issue (7), pp. 573-9, 2016.
NN, N., Z. B, N. - E. NE, G. - R. T, and S. - R. T, "Long-Term Changes in Aortic Length after Thoracic Endovascular Aortic Repair.", JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY, vol. Feb;27, issue (2), pp. 181-7, 2016.