Sahar Abou-Seri
Professor of Pharmaceutical Chemistry, Faculty of Pharmacy
(email)
EGFR tyrosine kinase inhibitors
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Abou-Seri, S. M.,
"
Synthesis and biological evaluation of novel 2,4'-bis substituted diphenylamines as anticancer agents and potential epidermal growth factor receptor tyrosine kinase inhibitors
",
European Journal of Medicinal Chemistry
, vol. 45 , pp. 4113-4121, 2010.
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4-d]pyrimidine
(1)
6-aryl-5-cyano thiouracils
(1)
a1-Adrenoceptor antagonists
(1)
antibacterial
(1)
anticancer.
(1)
antifungal
(1)
antitumor activity
(1)
Arylpiperazine derivatives
(1)
Coumarin
(2)
cytochrome P-450 enzymes inhibitors
(1)
EGFR tyrosine kinase inhibitors
(1)
Oxidative stress
(1)
phenylsulfonyl derivatives
(1)
pyrazoline
(1)
Pyrazolo[3
(1)
Quinazolinones
(1)
tyrosine kinase inhibitor
(1)
Vasorelaxant efficacy
(1)
Recent Publications
New proapoptotic chemotherapeutic agents based on the quinolone-3-carboxamide scaffold acting by VEGFR-2 inhibition.
Elaborating 5-(4-chlorophenyl)-1,3,4-thiadiazole scaffold with a p-tolyl sulfonamide moiety enhances cytotoxic activity: Design, synthesis, in vitro cytotoxicity evaluation, radiolabelling, and in vivo pharmacokinetic study
Design and synthesis of novel cytotoxic fluoroquinolone analogs through topoisomerase inhibition, cell cycle arrest, and apoptosis.
Fragment merging approach for the design of thiazole/thiazolidine clubbed pyrazoline derivatives as anti-inflammatory agents: Synthesis, biopharmacological evaluation and molecular modeling studies.
Development of novel anilinoquinazoline-based carboxylic acids as non-classical carbonic anhydrase IX and XII inhibitors.
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