8- Effect of low level laser therapy on neurovascular function of diabetic peripheral neuropathy
- Citation:
- Yamany, A. A., and P. D. Hayam M Sayed, "8- Effect of low level laser therapy on neurovascular function of diabetic peripheral neuropathy ", Journal of Advanced Research, vol. 3, issue 1, pp. 21-28, 2012.
Abstract:
Abstract
Diabetic neuropathy is the most common complication and greatest source of morbidity
and mortality in diabetic patients. Thirty male and female patients with painful diabetic neuropathy
and abnormal results from nerve conduction studies participated in this study. Their ages ranged
from 45 to 60 years with a mean of 52.1 ±SD 4.7 years. Patients were randomly assigned into
two equal groups of 15, an active laser group (laser group) and a placebo laser group (control
group). The laser group received scanning helium neon (He–Ne) infrared laser with wavelength
850 nm and density of 5.7 J/cm2, applied to the lumbosacral area and the plantar surface of the foot
for 15 min each site/session three times per week for four weeks (i.e. 12 sessions). Pain intensity via
visual analogue scale, bilateral peroneal motor nerves, sural sensory nerves conduction velocity and
amplitude and foot skin microcirculation, were measured pre- and post-treatment for both groups.
Pain was significantly decreased (p 6 0.05) and electrophysiological parameters and foot skin
microcirculation were significantly improved (p 6 0.05) in the laser group, while no significant
change was obtained in the control group. Low level laser therapy within the applied parameters
and technique could be an effective therapeutic modality in reducing pain and improving neurovascular
function in patients with diabetic polyneuropathy.
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