Biological and Chemical Assessment of Ochrosia elliptica Labill Leaves
- Citation:
- El-Shiekh, R. A., D. A. Al-Mahdy, M. S. Hifnawy, and E. Abdel-Sattar, Biological and Chemical Assessment of Ochrosia elliptica Labill Leaves, , vol. 46, issue 6, pp. 5247 - 5255, 2021.
Abstract:
Ochrosia elliptica Labill is a small tropical evergreen tree native to Oceania belonging to the Apocynaceae family. Eight alkaloids, two flavonoid glycosides and three phenolic acids were identified by LC/MS analysis. On the other hand, the quality and uniformity of the plant leaves were assessed through the determination of the total phenolic and flavonoid, in addition to total ash, acid-insoluble ash, water-soluble ash and moisture content. The total ethanolic and aqueous extracts of the leaves of O. elliptica as well as their fractions were investigated for their antinociceptive (analgesic) using tail-flick test and antimicrobial activities using agar well diffusion assay. Among the tested fractions, the results showed that the n-butanol fraction exhibited high potency as antinociceptive compared to indomethacin drug and as antifungal compared to amphotericin B.
Notes:
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