Publications

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2021
Cosmetic camouflage as an adjuvant to vitiligo therapies: Effect on quality of life, Bassiouny, Dalia Ahmed, Hegazy Rehab, Esmat Samia, and GAWDAT Heba I. , Journal of cosmetic Dermatology, Volume 20, Issue 1, p.159-165, (2021)
Effect of melanocyte keratinocyte transplantation procedure, using ablative CO2 laser and followed by NB-UVB phototherapy, on the expression of E-Cadherin and matrix metalloproteinase-2 in acral vitiligo: an immunohistochemical study, Bassiouny, Dalia Ahmed, Saleh Marwah Adly, abd el halim Dalia, and El Hawary Marwa , Journal of the Egyptian Women's Dermatologic Society, Volume 18, p.179-185, (2021)
Is Periungual Vitiligo an Intractable Localization?, Bassiouny, Dalia Ahmed, and Esmat Samia M. , Advances in Nail Disease and Management, (2021)
2020
Effect of Different Methods of Trypsinization on Cell Viability and Clinical Outcome in Vitiligo Patients Undergoing Noncultured Epidermal Cellular Suspension, Rasheed, Hoda M., Esmat Samia M., HEGAZY Rehab A., GAWDAT Heba I., Bassiouny Dalia M., Doss Sally S., Parsad Davinder, and Elkhouly Nesrin S. , Dermatologic Surgery, Volume 46, p.1307-1314, (2020)
Recipient site preparation by cryoblebbing in melanocyte keratinocyte transplantation procedure over the fingers in vitiligo: A pilot study, El Hawary, Marwa, Bassiouny Dalia Ahmed, Esmat Samia, Sobhi Rehab, Saleh Marwah Adly, abd el halim Dalia, Hegazy Rehab, GAWDAT HEBA, Ragab Nanis, SAMIR NESRIN, et al. , Dermatologic Therapy, Volume 10.1111/dth.14199, (2020)
Studying the effect of adding growth factors to the autologous melanocyte keratinocyte suspension in segmental vitiligo, S, Esmat, D Bassiouny, MA Saleh, AbdelHalim D, R Hegazy, M El Hawary, H Gawdat, Gouda H, M Khorshied, and N Samir , Dermatologic Therapy, Volume 33, p.e13368, (2020)
Value of silicone gel in prevention of cobblestoning following punch minigrafting in vitiligo, Anbar, Tag, Raheem Talal Abd El, Bassiouny Dalia Ahmed, Fawzy Marwa Mohamed, El Maadawi Zeinab, Farouk Noha, and Hassan Mohamed , Journal of Dermatological Treatment, Volume 13, p.1-8, (2020)
2017
Effect of Procedural-Related Variables on Melanocyte–Keratinocyte Suspension Transplantation in Nonsegmental Stable Vitiligo: A Clinical and Immunocytochemical Study, El-Zawahry, Bakr Mohamed, Esmat Samia, Bassiouny Dalia, Zaki Naglaa Sameh, Sobhi Rehab, Saleh Marwah A., Abdel-Halim Dalia, Hegazy Rehab, GAWDAT HEBA, SAMIR NESRIN, et al. , Dermatologic Surgery, Volume 43, Number 2, p.226–235, (2017) Abstract
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2016
Treatment of hypertrophic scars and keloids by fractional carbon dioxide laser: a clinical, histological, and immunohistochemical study., Azzam, O. A., Bassiouny D. A., El-Hawary M. S., El Maadawi Z. M., Sobhi R. M., and El-Mesidy M. S. , Lasers in medical science, 2016 Jan, Volume 31, Issue 1, p.9-18, (2016) Abstract

Treatment of keloids (K) and hypertrophic scars (HTS) is challenging. A few case reports reported good results in HTS treated by fractional CO2 laser. The aim of the present study was the assessment of the clinical response as well as histological changes in K and HTS treated by fractional CO2 laser and the role of matrix metalloproteinase 9 (MMP9) in the response. A randomized half of the scar was treated by fractional CO2 laser in 30 patients (18 K, 12 HTS) for a total of four sessions 6 weeks apart. Vancouver scar score (VSS) was done before and 1, 3, and 6 months after the last laser session by a blinded observer. Biopsies taken from normal skin, untreated scar, and treated scar tissue 1 and 3 months after the laser sessions were stained by HX & E for histological changes and Masson trichrome for collagen fiber arrangement. Immunohistochemical staining for MMP9 was done in before and 1 month after samples. Quantitative morphometric analysis was done for collagen and MMP9 by image analyzer. Nineteen patients completed the 6-month follow-up period (12 K, 7 HTS). VSS score was significantly lower in the treated compared to untreated areas after 3 and 6 months in both K and HTS but was mainly due to improved pliability of the scar. Histologically, dense inflammatory infiltrate and increased vascularity was apparent 1 month after laser sessions and disappeared at 3 months. Thinner better organized collagen bundle could be seen in 3 months after samples. MMP9 was significantly increased in after treatment samples but without significant correlation with VSS. Fractional CO2 resurfacing is safe but affects mainly pliability of K and HTS with collagen remodeling apparent 3 months after therapy. MMP9 may play a role in mechanism of action of CO2 laser in K and HTS.

Does the Duration of Hypertrophic Scars and Keloids Affect the Response to Fractional CO2 Laser?, Azzam, Omar A., Bassiouny Dalia A., and El-Hawary Marwa S. , (2016) Abstract

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Satisfaction of Keloids and Hypertrophic Scar Patients Following Fractional CO2 Laser, Azzam, Omar A., Bassiouny Dalia A., and El-Hawary Marwa S. , (2016) Abstract

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291 Effect of rituximab therapy on total CD25+ and CD4+ CD25+ cells of pemphigus vulgaris patients, El Zawahry, B., Bassiouny D., Hegazy R., Gawdat H., SHALABY S., and Saleh M. A. , Journal of Investigative Dermatology, Volume 136, Number 9, p.S210, (2016) Abstract
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Dermoscopic and Immunohistochemical Changes in Acquired Melanocytic Nevi following Narrow-Band Ultraviolet B Therapy, ZAHER, Hesham, Bassiouny Dalia, Abdel Hay R., SAMIR NESRIN, Ragab Nanees, and Sayed Safinaz , Dermatology, Volume 232, Number 3, p.273–278, (2016) Abstract
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Treatment of hypertrophic scars and keloids by fractional carbon dioxide laser: a clinical, histological, and immunohistochemical study, Azzam, O. A., Bassiouny D. A., El-Hawary M. S., El Maadawi Z. M., Sobhi R. M., and El-Mesidy M. S. , Lasers in medical science, Volume 31, Number 1, p.9–18, (2016) Abstract
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2015
Ablative CO2 fractional resurfacing in treatment of thermal burn scars: an open-label controlled clinical and histopathological study, El-Zawahry, Bakr M., Sobhi Rehab M., Bassiouny Dalia A., and Tabak Sahar A. , Journal of cosmetic dermatology, Volume 14, Number 4, p.324–331, (2015) Abstract
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Cutaneous manifestations in patients with haematological malignancy: a single-centre Egyptian study, Bassiouny, Dalia A., Raheem Heba Abdel M., Zawam Hamdy M., and Hamid Somaya Abdel E. , Journal of the Egyptian Women’s Dermatologic Society, Volume 12, Number 2, p.90–95, (2015) Abstract
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2014
Effect of procedural-related variables on melanocyte-keratinocye suspension transplantation in stable vitiligo: a clinical and immunohistochemical study, Bassiouny, D., El-Zawahry B. M., Esmat S., Sameh N., Sobhi R., Abdel-Halim D., Adly M., Hegazy R., Gawdat H., Samir N., et al. , Pigment Cell & Melanoma Research, Volume 27, Number 5, p.903, (2014) Abstract
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Tumor necrosis factor $\alpha$ promotor polymorphism and nonsegmental vitiligo: a molecular susceptibility marker in Egyptian women, Saleh, Nadia F., Nabil Nagla, Bassiouny Dalia A., and Khorshied Mervat M. , Journal of the Egyptian Women’s Dermatologic Society, Volume 11, Number 2, p.109–112, (2014) Abstract
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2013
Glutathione S-transferase M1 and T1 genetic polymorphism in Egyptian patients with nonsegmental vitiligo, Bassiouny, D. A., and Khorshied MM , Clinical and experimental dermatology, Volume 38, Number 2, p.160–163, (2013) Abstract
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PTPN22 gene polymorphism in Egyptian alopecia areata patients and its impact on response to diphencyprone immunotherapy, El-Zawahry, Bakr Mohamed, Azzam Omar Ahmed, Zaki Nagla Sameh, Abdel-Raheem Heba Mohamed, Bassiouny Dalia Ahmed, and Khorshied Mervat Mamdooh , Gene, Volume 523, Number 2, p.147–151, (2013) Abstract
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2012
A comparative study on efficacy of UVA1 vs. narrow-band UVB phototherapy in the treatment of vitiligo. , BM, El-Zawahry, DA Bassiouny, RM Sobhi, and E Abdel-Aziz , Photodermatol Photoimmunol Photomed, Volume Apr;28, Issue 2, p.84-90, (2012) Abstract

Background/Purpose: Narrow-band ultraviolet B (NB-UVB) is considered the most effective
and safe initial treatment for moderate-to-severe vitiligo but phototoxicity and possible
carcinogenicity are the reported side effects. Ultraviolet A1 (UVA1) phototherapy has overlapping
biological effects to NB-UVB and is relatively free of side effects associated with
other phototherapy regimens.
Methods: Forty patients with vitiligo were included in this prospective, randomized controlled
comparative clinical trial.Twenty patients received NB-UVB and 20 received UVA1 three
times weekly for 12 weeks. The UVA1 group was divided into two subgroups. Ten patients
received moderate and 10 received low dose of UVA1. Serum samples were collected before
and after 36 sessions to assess soluble interleukin 2 receptor level. Patients were clinically
evaluated before therapy then monthly according to Vitiligo Area Scoring Index (VASI) and
Vitiligo European Task Force (VETF) scores. In addition, extent of response was determined
by a blinded dermatologist comparing before and after therapy photographs. Pattern of
response and side effects were recorded.
Results: NB-UVB was superior to UVA1 with a significant difference in blinded dermatological
assessment (P < 0.001), percentage change in VASI score (P < 0.001) and percentage
change in VETF area score (P = 0.001). No significant difference in side effects was observed
between both groups. Comparing UVA1 subgroups, better response in moderate-dose group
was found as regard to percentage change in VASI (P < 0.001) and percentage change in
VETF area score (P = 0.001), while no significant difference was found in blinded dermatological
assessment (P = 0.121).
Conclusion: NB-UVB phototherapy remains to be an effective and safe therapeutic option in
vitiligo. Response to UVA1 in vitiligo seems to be dose dependent and seems to be of limited
value in treatment of vitiligo as a monotherapy. Further studies combining it with other lines
of therapy such as systemic steroids may prove beneficial.

Glutathione S-transferase M1 and T1 genetic polymorphism in Egyptian patients with nonsegmental vitiligo., DA, Bassiouny, and MM Khorshied , Clin Exp Dermatol, Volume Mar;38, Issue 2, p.160-3, (2012) Abstract

Oxidative stress and accumulation of free radicals might play a role in the pathogenesis
of vitiligo. Glutathione S-transferase (GST) is a multigene family of enzymes that
detoxify oxidative stress products. In this study, genotyping by multiplex PCR of
GSTM1 and GSTT1 in 101 women with nonsegmental vitiligo vulgaris and 101 agematched
healthy female volunteers showed that only the GSTM1 null genotype
(P = 0.04) was significantly overexpressed in patients with vitiligo. Analysis of the
combined effect of GSTM1 and GSTT1 genotyping identified a significant association of
risk for vitiligo with the GSTT1 ⁄ GSTM1 double-null type only (P = 0.01; OR = 2.69;
95% CI 1.12–6.46). Age of onset of vitiligo was significantly earlier in patients with the
T1 null genotype (P < 0.01) and those with the T1) ⁄ M1+ and T1) ⁄ M1) combined
genotypes (P < 0.01 and P = 0.01, respectively). In conclusion, the GSTM1 gene and
the GSTM1 ⁄ GSTT1 double-null genotype may be a risk factor for vitiligo in Egyptian
patients. Inability to cope with oxidative stresses because of GST deficiency may cause
early disease onset.

A comparative study on efficacy of UVA1 vs. narrow-band UVB phototherapy in the treatment of vitiligo, El-Zawahry, Bakr Mohamed, Bassiouny Dalia Ahmed, Sobhi Rehab Mohamed, Abdel-Aziz Eman, Zaki Naglaa Sameh, Habib Dawoud Fakhry, and Shahin Dalia Mamdouh , Photodermatology, photoimmunology & photomedicine, Volume 28, Number 2, p.84–90, (2012) Abstract
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2011
Autologous melanocyte-keratinocyte suspension in the treatment of vitiligo, BM, El-Zawahry, NS Zaki, DA Bassiouny, and RM Sobhi , J Eur Acad Dermatol Venereol, Volume 25, Issue 2, p.215-20, (2011) Abstract

Background In stable vitiligo, several techniques of autologous transplantation of melanocytes are used. Autologous melanocyte transplantation of non-cultured melanocytes is one of those techniques with variable reported outcomes.
Objective The objective of this study was to evaluate the response to autologous melanocyte–keratinocytes suspension transplantation in cases of stable vitiligo.
Methods A total of 25 cases of vitiligo were treated by autologous melanocyte–keratinocytes suspension transplantation. After 6–17 months, patients’ response was evaluated according to the extent of pigmentation (excellent 90–100%, good 50–89%, fair 20–49% and poor response <20%).
Results Of the 25 patients treated, 22 continued the follow-up period. Five (23%) patients showed excellent response, 7 (32%) good, 6 (27%) fair and 4(18%) showed poor response.
Conclusion Unlike transplantation of cultured melanocytes, which requires experience in culture technique,autologous melanocyte–keratinocytes suspension transplantation is an easy economic technique, which may be used in resistant areas of stable vitiligo.

Role of interleukin-17 in the pathogenesis of vitiligo, DA, Bassiouny, and O Shaker , Clin Exp Dermatol, Volume 36, Issue 3, p.292-7, (2011) Abstract

Background. Skewing of the immune response towards T helper (Th)1 or Th17 and away from regulatory T cells (Tregs) and Th2 cells may be responsible for the development and progression of autoimmune disease. An autoimmune theory has been proposed in the pathogenesis of vitiligo. No previous reports have investigated
alterations in IL-17 produced by Th17 cells in lesional skin in vitiligo.
Aim. To investigate the role of IL-17 in the pathogenesis of vitiligo by assessing its
levels in lesional skin and serum of patients with vitiligo compared with controls.
Methods. In total, 30 patients with vitiligo and 20 controls matched for age and gender were enrolled in the study. Serum and tissue IL-17 levels were measured by ELISA and compared between both groups for correlations with age, gender, family history, disease duration, activity of vitiligo and percentage of involved body surface
area.
Results. A significant difference between patients and healthy controls was found for both serum and tissue IL-17 levels (P < 0.001 for both). Significant positive correlations were found between disease duration and IL-17 level in both serum (r = 0.42,
P = 0.02) and lesional skin (r = 0.45, P < 0.015); between extent of vitiligo and IL-17 levels in both serum (r = 0.65, P < 0.001) and skin (r = 0.48, P < 0.05); and between the serum and the tissue IL-17 levels in patients with vitiligo (r = 0.54,
P = 0.002).
Conclusions. Multiple factors have been implicated in the pathogenesis of vitiligo. The increased levels of IL-17 we found in serum and lesional skin suggest an important role for this cytokine in the pathogenesis of vitiligo

Subcision versus 100% trichloroacetic acid in the treatment of rolling acne scars, SA, Ramadan, MH El-Komy, DA Bassiouny, and SA El-Tobshy , Dermatol Surg, Volume 37, Issue 5, p.626-33, (2011) Abstract

BACKGROUND Acne scarring is common but surprisingly difficult to treat. Newer techniques and
modifications to older ones may make this refractory problem more manageable. The 100% trichloroacetic acid (TCA) chemical reconstruction of skin scars (CROSS) method is a safe and effective single
modality for the treatment of atrophic acne scars, whereas subcision appears to be a safe technique that provides significant improvement for rolling acne scars.
OBJECTIVE To compare the effect of the 100% TCA CROSS method with subcision in treating rolling acne scars.
METHODS Twenty patients of skin types III and IV with bilateral rolling acne scars received one to three sessions of the 100% TCA CROSS technique for scars on the left side of the face and subcision for scars on the right side.
RESULTS The mean decrease in size and depth of scars was significantly greater for the subcision side than the 100% TCA CROSS (po.001). More side effects in the form of pigmentary alteration were observed with the 100% TCA CROSS method.
CONCLUSION For rolling acne scars in patients with Fitzpatrick skin types III and IV, subcision shows better results with fewer side effects than the 100% TCA CROSS technique, although further decrease in scar depth with time occurs more significantly after 100% TCA CROSS

Sulfasalazine and pentoxifylline in psoriasis: a possible safe alternative, el-Mofty M, el-Darouti M, H Rasheed, and DA Bassiouny , J Dermatolog Treat, Volume 22, Issue 1, p.31-7, (2011) Abstract

Background: Conventional therapy of extensive psoriasis is effective but has complications. Biologics are safer but expensive.
Objective: To assess the efficacy of sulfasalazine and pentoxifylline, which have TNF antagonizing and anti-proliferative action in the treatment of psoriasis. Methods: In this randomized controlled trial, 32 patients with extensive psoriasis were divided into four groups: group A received sulfasalazine; group B received pentoxifylline; group C received both drugs; and group D
received methotrexate. The Psoriasis Area and Severity Index (PASI) score was done at weeks 0, 2, 4, 6 and 8.
Results: A significant reduction in PASI score occurred in groups C and D (p = 0.043 and 0.018, respectively). A significantly higher percentage of PASI score reduction occurred in group D compared with groups A, B and C (p = 0.006, 0.003 and 0.030, respectively). An excellent response occurred in one patient (14.3%) in group D. A very good response occurred in two patients
(22.2%) in group C, and in five patients (71.4%) in group D. A moderate response occurred in three patients (37.5%) in group A, one patient (12.5%) in group B, and one patient (14.3%) in group D. Conclusion: Although incomparable to methotrexate, combined sulfasalazine and pentoxifylline produced a good response in cases of extensive psoriasis. Multicentre studies are needed to validate these results

Autologous melanocyte–keratinocyte suspension in the treatment of vitiligo, El-Zawahry, B. M., Zaki NS, Bassiouny D. A., Sobhi R. M., Zaghloul A., Khorshied MM, and Gouda H. M. , Journal of the European Academy of Dermatology and Venereology, Volume 25, Number 2, p.215–220, (2011) Abstract
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Role of interleukin-17 in the pathogenesis of vitiligo, Bassiouny, D. A., and Shaker O. , Clinical and experimental dermatology, Volume 36, Number 3, p.292–297, (2011) Abstract
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Subcision versus 100% trichloroacetic acid in the treatment of rolling acne scars, RAMADAN, SHAHIRA ABD EL-RAHMAN, EL-KOMY MOHAMED HUSSEIN MEDHAT, Bassiouny Dalia Ahmed, and EL-TOBSHY SEHAM AHMED , Dermatologic Surgery, Volume 37, Number 5, p.626–633, (2011) Abstract
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Sulfasalazine and pentoxifylline in psoriasis: a possible safe alternative, El-Mofty, Medhat, El-Darouti Mohamed, RASHEED Hoda, Bassiouny Dalia Ahmed, Abdel-Halim Mona, Zaki Naglaa Sameh, El-Hanafy Ghada, El-Hadidi Heba, Azzam Omar, El-Ramly Amany, et al. , Journal of Dermatological Treatment, Volume 22, Number 1, p.31–37, (2011) Abstract
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2010
Bcl-2 expression in mycosis fungoides before and after PUVA therapy, D, Mahgoub, N El-Eishy, AM El-Tawdy, and DA Bassiouny , Photodermatol Photoimmunol Photomed, Volume 26, Issue 2, p.107-9, (2010) Abstract

PUVA is the first therapeutic choice in early stages of mycosis fungoides (MF). In this study the effect of PUVA on bcl-2 expression in MF was assessed in 15 patients (three stage Ia and 12 stage Ib) and 10 controls. Two biopsies were taken from each patient before and after 24 sessions of PUVA therapy. Histopathological assessment and immunohistochemical staining for bcl-2 was performed and showed positive bcl-2 staining of lymphocytes in 53% of MF cases (8/15) before PUVA, with no statistically significant difference in the bcl-2 level before and after PUVA therapy (P value 0.3). A statistically significant difference was found in the bcl-2 level between control samples and MF patients’ biopsies before (P value 0.02) and after PUVA therapy (P value 0.011). In conclusion, a lack of decline in the bcl-2 level and the absence of clinical or histopathological correlation with the bcl-2 level before and after PUVA therapy in MF patients suggest that PUVA-induced apoptosis in MF cases may occur through
pathways other than bcl-2 inhibition.

Five-year experience in the treatment of alopecia areata with DPC, BM, El-Zawahry, DA Bassiouny, A Khella, and NS Zaki , J Eur Acad Dermatol Venereol, Volume 24, Issue 3, p.264-9, (2010) Abstract

Background The effectiveness of Diphencyprone (DPC) in alopecia areata (AA) was demonstrated in several studies with highly variable response rates ranging from 5% to 85%.
Objective The response rate and variable factors affecting the prognosis were studied focusing on long-term follow-up with or without maintenance therapy.
Methods A total of 135 cases of AA were treated with DPC. Patients were divided into five groups according to the area of scalp affected: Grade 1 AA: 25–49% scalp affection; Grade 2 AA: 50–74% scalp affection; Grade 3 AA: 75– 99% scalp affection; alopecia totalis and alopecia universalis. An initial response was defined as appearance of new terminal hair within treated sites. Excellent response was defined as terminal hair covering >75% of the scalp. Relapse meant >25% hair loss. Maintenance therapy meant ongoing therapy once every 1–4 weeks after excellent response. Follow-up was performed to detect any relapse of AA.
Results Ninety-seven patients continued therapy for ‡3 months. After an initial 3 month lag, cumulative excellent response was seen in 15 patients (15.4%), 47 patients (48.5%), 51 patients (52.6%) and 55 patients (55.7%) after 6, 12, 18 and 24 months respectively in a mean median time of 12 months. The only patient variable affecting the prognosis was baseline extent of AA. Excellent response was seen in 100%, 77%, 54%, 50% and 41% in Grade 1, Grade 2, Grade 3, AA totalis and AA universalis patients respectively. Side-effects were few and tolerable. Hair fall >25% occurred in 17.9% of patients on maintenance and 57.1% of patients without maintenance therapy (P-value = 0.025).
Conclusion Diphencyprone is an effective and safe treatment of extensive AA. A long period of therapy is needed and will increase the percentage of responders especially in alopecia totalis and universalis. Maintenance therapy is
recommended to reduce the risk of relapse

Punch grafting in vitiligo; Different factors which affect the results, DA, Bassiouny , J Egypt Women Dermatol Soc, Volume 7, Issue 1, p.16-21, (2010) Abstract

Background. In stable vitiligo several techniques of autologous melanocyte transplantation are used. Punch grafting is the easiest and least expensive. Objective. To assess the effect of patient and treatment variables on results of punch grafting. Patients and methods. Thirty-two vitiligo lesions in twenty patients were treated by punch grafting. After grafting, 13 patients received PUVA and 7 patients received topical psoralen & sun (PUVASOL) for 3 months. Response was assessed according to extent of pigmentation (Excellent > 90%, very good 75 - 90%, good 50 - 75% and poor response ≤ 50%). Mean margin of pigment spread (MPS) in mm was calculated for each patient. The effect of different factors on the response and development of side-effects was assessed in lesions achieving > 50% pigmentation (good - excellent response). Results. Nine lesions (28%) showed excellent, 15 (47%) very good, 5 (16%) good and 3 (9%) a poor response. The mean MPS was 3.7 ± 0.78 mm. Age had a significant positive correlation with MPS (r = 0.488, p = 0.007) while skin type and region treated had none. Punch sizes and the difference between donor and recipient punches did not affect MPS statistically. Donor punch size (r = - 0.808, p = 0.000) and recipient punch size (r = - 0.801, p = 0.000) had a significant negative correlation with the number of grafts remaining in place. No significant difference in MPS was found between patients on PUVA vs PUVASOL therapy after grafting (p = 0.068). Cobble-stoning occurred in 5 lesions (16%). The smaller the donor (p = 0.002) and recipient (p = 0.003) punch sizes the less was the cobble-stoning.Conclusion. Punch grafting is an effective, easy and inexpensive treatment of localized stable vitiligo. Of the different studied variables, age had a significant positive correlation with MPS. Using smaller punch sizes improved the response and reduced cobble-stoning. No significant difference in MPS was found between patients receiving PUVA therapy vs topical PUVASOL after grafting, making this technique applicable for patients with no access to phototherapy centers. (J Egypt Women Dermatol Soc 2010; 7: 16 - 21)

Bcl-2 expression in mycosis fungoides before and after PUVA therapy, Weshahy, Hani, Mahgoub Doa, El-Eishy Nermine, El-Tawdy Amira Mohamed, Bassiouny Dalia Ahmed, Hunter Nahla, and Hindawi Ali , Photodermatology, photoimmunology & photomedicine, Volume 26, Number 2, p.107–109, (2010) Abstract
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Bcl-2 expression in mycosis fungoides before and after PUVA therapy, Mahgoub, D., El-Eishy N., El-Tawdy A. M., and Bassiouny D. A. , Photodermatol Photoimmunol Photomed, Volume 26, Number 2, (2010) Abstract
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Five-year experience in the treatment of alopecia areata with DPC, El-Zawahry, B. M., Bassiouny D. A., Khella A., and Zaki NS , Journal of the European Academy of Dermatology and Venereology, Volume 24, Number 3, p.264–269, (2010) Abstract
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2009
2007
Ultrasound biomicroscopy in the diagnosis of skin diseases , BM, El-Zawahry, SA Ramadan, H El-Choweikh, and DA Bassiouny , Eur J Dermatol 2007, Volume 17, Issue 6, p.469-75, (2007) Abstract

Ultrasound scanning is becoming an important diagnostic tool in dermatology.The major advantages of this technique are its non invasive
non-ionizing nature and its relatively low cost.We aimed to evaluate the accuracy of ultrasound biomicroscopy (UBM) in the diagnosis of eight
skin disorders namely, morphea, keloid, lichen planus, chronic eczema, psoriasis, port wine stain, seborrheic keratosis, and photo-aged skin,
through correlation of its findings with clinical and pathological assessment. Fifty seven patients with the above diseases were examined by
ultrasound biomicroscopy (UBM). Two areas, one of normal skin and the other from lesional skin, were examined for each patient. Skin biopsies were taken from the same lesion examined by UBM. In morphea, the dermal echogenicity was increased and the thickness of morphea
plaques correlated significantly with disease severity. Keloids appeared as low echogenic images. In lichen planus and chronic eczema
the dermis appeared as sound shadow. In psoriasis, an intermediate zone between the epidermis and dermis (B zone) was detected. Its thickness correlated significantly with the PASI score. Port wine stain lesions appeared hypoechoic. Seborrheic keratosis appeared as a sound shadow. In photo-aged skin a subepidermal low echogenic band (SLEB) was detected. We conclude that UBM is a non-invasive diagnostic tool in dermatology which can be used to give valuable information about disease progress and the effectiveness of therapy

Combined trichloroacetic acid peel and topical ascorbic acid versus trichloroacetic acid peel alone in the treatment of melasma: a comparative study, Soliman, Mohsen Mohamed, RAMADAN SHAHIRA ABD EL-RAHMAN, Bassiouny Dalia Ahmed, and others , Journal of cosmetic dermatology, Volume 6, Number 2, p.89–94, (2007) Abstract
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Tourism