Otu, A., M. Hashmi, A. H. M. E. D. M. MUKHTAR, A. Kwizera, S. Tiberi, B. Macrae, A. Zumla, M. W. Dünser, and M. Mer, "The critically ill patient with tuberculosis in intensive care: Clinical presentations, management and infection control.", Journal of critical care, vol. 45, pp. 184-196, 2018. Abstract

Tuberculosis (TB) is one of the top ten causes of death worldwide. In 2016, there were 490,000 cases of multi-drug resistant TB globally. Over 2 billion people have asymptomatic latent Mycobacterium tuberculosis infection. TB represents an important, but neglected management issue in patients presenting to intensive care units. Tuberculosis in intensive care settings may present as the primary diagnosis (active drug sensitive or resistant TB disease). In other patients TB may be an incidental co-morbid finding as previously undiagnosed sub-clinical or latent TB which may re-activate under conditions of stress and immunosuppression. In Sub-Saharan Africa, where co-infection with the human immunodeficiency virus and other communicable diseases is highly prevalent, TB is one of the most frequent clinical management issues in all healthcare settings. Acute respiratory failure, septic shock and multi-organ dysfunction are the most common reasons for intensive care unit admission of patients with pulmonary or extrapulmonary TB. Poor absorption of anti-TB drugs occurs in critically ill patients and worsens survival. The mortality of patients requiring intensive care is high. The majority of early TB deaths result from acute cardiorespiratory failure or septic shock. Important clinical presentations, management and infection control issues regarding TB in intensive care settings are reviewed.

Bezinover, D., D. Dirkmann, J. Findlay, C. Guta, M. Hartmann, R. Nicolau-Raducu, A. H. M. E. D. M. MUKHTAR, M. Moguilevitch, E. Pivalizza, D. Rosenfeld, et al., "Perioperative Coagulation Management in Liver Transplant Recipients.", Transplantation, vol. 102, issue 4, pp. 578-592, 2018. Abstract

We review contemporary coagulation management for patients undergoing liver transplantation. A better understanding of the complex physiologic changes that occur in patients with end-stage liver disease has resulted in significant advances in anesthetic and coagulation management. A group of internationally recognized experts have critically evaluated current approaches for coagulopathy detection and management. Strategies for blood component and factor replacement have been evaluated and recommended therapies proposed. Pharmacologic treatment and prevention of coagulopathy, management of patients receiving antiplatelet medications, and the role of transesophageal echocardiography for early detection and management of thromboses are presented.

Shrestha, G. S., A. Kwizera, G. Lundeg, J. I. Baelani, L. C. P. Azevedo, R. Pattnaik, R. Haniffa, S. Gavrilovic, N. T. H. Mai, N. Kissoon, et al., "International Surviving Sepsis Campaign guidelines 2016: the perspective from low-income and middle-income countries.", The Lancet. Infectious diseases, vol. 17, issue 9, pp. 893-895, 2017 Sep.
MUKHTAR, A. H. M. E. D. M., and H. Dabbous, "Modulation of splanchnic circulation: Role in perioperative management of liver transplant patients.", World Journal of Gastroentrology, vol. 22, issue 4, pp. 1582-92, 2016.
I, R., M. H, Nabil N, A. S, H. A, E. adawy A, Ahmed M, and Mukhtar A, "Evaluation of Perfusion Index as a Predictor of Vasopressor Requirement in Patients with Severe Sepsis", Shock, vol. 44, issue 6, pp. 554-559, 2015.
Mukhtar A, O. G, H. A, and A. - F. F, "Intraoperative terlipressin therapy reduces the incidence of postoperative acute kidney injury after living donor liver transplantation", J Cardiothorac Vasc Anesth, vol. 29, issue 3, pp. 678-683, 2015.
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