Publications

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Journal Article
Samer, M., E. A. Imam, A. A. Shamaa, and A. A. Mostafa, "Establishment of Amniotic Membrane Bank for Orthopaedic Surgery in dogs: Clinical and Radiographic Assessment. ", Journal of the egyptian veterinary medical association Vol 74(4)519-531, 2014.
Abdallah1, A. N. - E., A. A. Shamaa, and O. S. el-Tookhy, "Ethidium Bromide Induced Demyelination of The Central Nervous System in A Dog Model of Secondary Progressive Multiple Sclerosis", Journal of Current Veterinary Research, vol. 2, issue 1, 2020.
el-Tookhy, O. S., A. A. Shamaa, and A. N. Abdallah, "Ethidium Bromide Induced Spinal Cord Demyelination in a Multiple Sclerosis Dog", Bioscience Research , vol. 15, issue 3, 2018.
Abdallah, A. N., A. A. Shamaa, O. S. el-Tookhy, and E. A. M. El-Mottaleb, "Evaluation of Low Level Laser activated stromal vascular fraction as a single procedure for treatment of experimental chondral defects. ", Asian Journal of Animal Sciences 10 (1): 15-28. , 2016.
Sabry, D., A. Mostafa1, D. Mekawey, Z. Altaib, A. Shamaa, A. Hany, D. M, A. E. Hassib, N. E. Ibrahim, and W. A. Khalifa, "An experimental model: intrauterine adhesion versus sub endometrial fibrosis", Biomedical Research , vol. 29, issue 17, pp. 3311-3318, 2018.
El-Marzouky, H. H., F. A. Khalifa, G. A. Khalifa, A. A. Shamaa, M. H. Farid, and S. A. Elsayed, "Experimental Study of Bone Defect Repair Using Centrifuged and Non-Centrifuged Bone Marrow Aspirate", ADJ-for Girls, vol. 1, pp. 61-66, 2019.
el-Tookhy, O. S., A. A. Shamaa, and A. N. Abdallah, "Failure of endogenous remyelination following Ethidium Bromide Injection in Dogs’ spinal cord: A Progressive Model of Multiple sclerosis. ", Bioscience Research., vol. 15, issue 3, 2018.
Saravanan, S., N. Sareen1, E. Abu-El-Rub, H. Ashour, G. L. Sequiera, H. I. Ammar, V. Gopinath, A. A. Shamaa, S. S. E. Sayed, M. Moudgil, et al., "Graphene Oxide-Gold Nanosheets Containing Chitosan Scaffold Improves entricular Contractility and Function After Implantation into Infarcted Heart", SCIENTIFIC RepOrtS , vol. 8, pp. 15069, 2018.
el-Tookhy, O. S., A. A. Shamaa, G. G. Shehab, A. N. Abdallah, and O. M. Azzam, "Histological evaluation of experimentally induced critical size defect skin wounds using exosomal solution of mesenchymal stem cells derived microvesicles.", . International journal of stem cells , issue septamper 2, 2017.
Abdelmonema, M., N. N. Shahina, L. A. Rashed, H. A. A. Aminc, A. A. Shamaa, and A. A. Shaheena, "Hydrogen sulfide enhances the effectiveness of mesenchymal stem cell. therapy in rats with heart failure: In vitro preconditioning versus in vivo codelivery. ", Biomedicine & Pharmacotherapy , vol. 112, 2019.
Farghali, H. A., K. K. Ali, and A. A. Shamaa, "Incidence of the Most Common Surgical Affections among Sheep and Goats Admitted to a Referral Hospital in the State of Kuwait", Advances in Animal and Veterinary Sciences,, vol. 8, issue 2, pp. 41-57, 2020.
Mahmoud, M. M., E. Hassan, L. A. Rashed, and A. Shamaa, "Increase Renal CYP2C23 Expression Using Thiazide Diuretics Attenuate the Progression of Cardiovascular Disease in Rat Model of Chronic Renal Failure", Med. J. Cairo Univ, vol. 86, issue 5, pp. 2511-2519, 2018.
Doaa H. Elgohary, N. A. M. Mona M. Salem, Tamer F. Khalifa, Elham A. Hassan, and A. A. Shamaa, "Innovative textile technology for dilated cardiomyopathy:” Shape formation of knitted cardiac support mesh”", International journal of Sceince and Research (IJSR),, issue 4(10):504-511., 2015.
Elgohary, D. H., T. F. Khalifa, M. M. Salem, N. M. Aly, E. Hassan, and A. A. Shamaa, "Knitted cardiac mesh to support left ventricular hypertrophy: an in vivo experimental study: supporting left ventricular hypertrophy using cardiac support mesh (2022)", Research Journal of Textile and Apparel, issue 26 (4), JCI: 0.38, pp. 485-499., 2022.
Salem, N., E. Ehsan, E. A. Ghany, D. Sabry, and A. Shamaa, "Mesenchymal stem cells transplantation attenuates brain injury in experimentally induced neonatal hypoxia", Tissue and Cell, 2018.
Sabry, D., A. Mostafa, S. Marzouk, W. Ibrahim, H. H. M. Ali, A. Hassan, and A. Shamaa, "Neupogen and mesenchymal stem cells are the novel therapeutic agents in regeneration of induced endometrial fibrosis in experimental rats.", Bioscience reports, vol. 37, issue 5, 2017 Oct 31. Abstract

Endometrial fibrosis is the presence of intrauterine adhesions (IUAs) after any uterine surgery or curettage and it results in infertility and recurrent pregnancy loss. We evaluated the role of human mesenchymal stem cells (hMSCs) as a therapeutic agent of endometrial fibrosis. We also compared the effect of MSCs with the effect of estrogen and neupogen either each alone or as a combined therapy with MSCs. This experimental study was performed on 84 albino rats which were divided into seven groups (=12 rats/group) as follows, 1: normal control rats, 2: induced fibrosis, 3: induced fibrosis that received oral estrogen, 4: induced fibrosis that received hMSCs, 5: induced fibrosis that received hMSCs and estrogen, 6: induced fibrosis that received neupogen, and 7: induced fibrosis that received hMSCs and neupogen. The extent of fibrosis, vascularization, and inflammation were evaluated by; qRT-PCR for interleukin 1 (IL-1), interleukin 6 (IL-6), TNF, vascular endothelial growth factor (VEGF), transforming growth factor-β (TGF-β), and RUNX; ELISA for connective tissue growth factor (CTGF); Western blotting for collagen-I; immunohistochemistry examination for VEGF and RUNX-2; and histopathological assessment. In therapeutic groups either by hMSCs alone or combined with estrogen or neupogen; fibrosis and inflammation (IL-1, IL-6, TNF, TGF-β, RUNX, CTGF, and collagen-I) were significantly decreased but vascularization (VEGF) was significantly increased (<0.05) compared with induced fibrosis group. The most significant result was obtained in fibrosis that received combined therapy of hMSCs and neupogen (=0.000). Stem cells and neupogen are a highly effective alternative regenerative agents in endometrial fibrosis.

Mannaa M, S. AA, R. A. M. Shawky A, Hassan IM, and A. - S. A. M., "A novel surgical technique for treatment of cervical vertebral stenotic myelopathy (wobbler syndrome) in a filly.", J Equine Vet Sci. , pp. 104493, 2023.
Ali, K. K., H. A. Farghali, and A. A. Shamaa, "Orthopedic surgical affection in sheep and goats in state of Kuwait", International Journal of Applied Research, vol. 6, issue 1, pp. 44-49, 2020.
Elham A. Hassan, Faisal A. Torad, and A. A. Shamaa, "Pneumopericardium secondary to pneumomediastinum in Golden Retriever dog.", Topics in Compan Anim Medicine 30;62-64. , 2015.
Abuowarda1, M., M. Amer, A. Shamaa, A. A. G. Shehab3, and M. Hassan, "A preliminary study of endoscopic diagnosis of gastric ulcer in Egyptian donkeys (Equus asinus) parasitized by Gasterophilus intestinalis (Diptera: Oestridae) ", Bulgarian Journal of Veterinary Medicine, issue https://doi.org/10.47278/journal.ijvs. 2021, 2020.
Shamaa, A., D. E. Hanafy2, T. F. Khalifa, M. M. Salem, G. G. Shehab, N. M. Aly, and E. HASSAN, "Pressure-induced left ventricular hypertrophy in canine model of aortic stenosis using nylon tie", Acta Scientiarum. Biological Sciences, vol. 42, 2020.
Shoukry, H. S., H. I. Ammar, L. A. Rashed, M. B. Zikri, A. A. Shamaa, S. G. Abou Elfadl, E. A. - A. Rub, S. Saravanan, and S. Dhingra, "Prophylactic supplementation of resveratrol is more effective than its therapeutic use against doxorubicin induced cardiotoxicity.", PloS one, vol. 12, issue 7, pp. e0181535, 2017. Abstract

Resveratrol (RSV), a polyphenolic compound and naturally occurring phytoalexin, has been reported to exert cardio-protective effects in several animal studies. However, the outcome of initial clinical trials with RSV was less effective compared to pre-clinical studies. Therefore, RSV treatment protocols need to be optimized. In this study we evaluated prophylactic versus therapeutic effect of resveratrol (RSV) in mitigating doxorubicin (Dox)-induced cardiac toxicity in rats. To investigate prophylactic effects, RSV was supplemented for 2 weeks along with Dox administration. After 2 weeks, Dox treatment was stopped and RSV was continued for another 4 weeks. To study therapeutic effects, RSV treatment was initiated after 2 weeks of Dox administration and continued for 4 weeks. Both prophylactic and therapeutic use of RSV mitigated Dox induced deterioration of cardiac function as assessed by echocardiography. Also RSV treatment (prophylactic and therapeutic) prevented Dox induced myocardial damage as measured by cardiac enzymes (LDH and CK-MB) in serum. Which was associated with decrease in Dox induced myocardial apoptosis and fibrosis. Interestingly our study also reveals that prophylactic use of RSV was more effective than its therapeutic use in mitigating Dox induced apoptosis and fibrosis in the myocardium. Therefore, prophylactic use of resveratrol may be projected as a possible future adjuvant therapy to minimize cardiotoxic side effects of doxorubicin in cancer patients.

El-Rahma, S. A. S., M. S. Amer, M. H. Hassan, H. M. Fahmy, and A. A. Shamaa, "Repair of experimentally induced femoral chondral defect in a rabbit model using Lyophilized growth promoting factor extracted from horse blood platelets (L-GFequina)", Injury, issue Ms. No. JINJ-D-21- accepted02200R1, 2022.
Abd El-Rahman, S. S., M. Samer, H. M. Fahmy, and A. A. Shamaa, "Repair of experimentally induced femoral chondral defect in a rabbit model using Lyophilized growth promoting factor extracted from horse blood platelets (L-GFequina) (2022) ", Injury, issue 53 (4), pp. 1375-1384, 2022.
98) Farghali, H. A., K. K. Ali, and A. A. Shamaa, "Review on The Common Surgical Affections in Sheep and Goats", Journal of Applied Veterinary Sciences, vol. 5, issue 3, pp. 40-48, 2020.