Publications

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Report
Hafez, M. A. E. D., A. A. Shamaa, and A. A. M. Salem, A tool for custom-made instruments and implant for artificial knee joint of dogs, : US Patent App. 15 , 2018.
Journal Article
Hassan, M. H., S. A. S. El-Rahman, M. S. Amer, H. M. Fahmy, and A. A. Shamaa, ) Effect of Lyophilized Growth Factors (LGF) Derived from Equine Platelets on Experimentally Induced Skin Wound Healing in Mongrel Dogs, , 2020.
Hasssan, M. H.; O. E. -tookhy; E. H. S. A., D. S. Abdelfatah, G. G. Shehab, and A. A. Shamaa, "A canine model of carbon tetrachloride (CCl4) induced liver cirrhosis: II. Ultrasongraphic and histopathological study. ", Veterinary Medical Journal Giza (VMJG),, vol. 62(1).6-13 January., 2016.
Hassan, M. H., A. N. Abdallah, A. A. Shamaa, and A. M. Abu-Seida, "Clinical Effect of Mesenchymal Stem cell-Derived Microvesicles as Adjunctive Treatment to Surgery on Healing of Distal Limb Chronic Wounds in Arabian Horses.", Egypt. J. Vet. Sci. Vol. 55,No. 6, pp. 1765-1774, issue Vol. 55,No. 6, pp. 1765-1774, pp. 1765-1774, 2024.
Sabrya, D., A. Shamaa, M. Amer, O. El-Tookhy, A. Abdallahc, D. M. A. E. Hassibd, E. Amer, and A. E. Amir, "The Effect of Mesenchymal Stem Cell Derived Microvesicles in Repair of Femoral Chondral Defects in Dogs", Journal of Musculoskeletal Research , vol. Mar 08, 2018.
Sabry, D., A. Mostafa1, D. Mekawey, Z. Altaib, A. Shamaa, A. Hany, D. M, A. E. Hassib, N. E. Ibrahim, and W. A. Khalifa, "An experimental model: intrauterine adhesion versus sub endometrial fibrosis", Biomedical Research , vol. 29, issue 17, pp. 3311-3318, 2018.
Mahmoud, M. M., E. Hassan, L. A. Rashed, and A. Shamaa, "Increase Renal CYP2C23 Expression Using Thiazide Diuretics Attenuate the Progression of Cardiovascular Disease in Rat Model of Chronic Renal Failure", Med. J. Cairo Univ, vol. 86, issue 5, pp. 2511-2519, 2018.
Elgohary, D. H., T. F. Khalifa, M. M. Salem, N. M. Aly, E. Hassan, and A. A. Shamaa, "Knitted cardiac mesh to support left ventricular hypertrophy: an in vivo experimental study: supporting left ventricular hypertrophy using cardiac support mesh (2022)", Research Journal of Textile and Apparel, issue 26 (4), JCI: 0.38, pp. 485-499., 2022.
Sabry, D., A. Mostafa, S. Marzouk, W. Ibrahim, H. H. M. Ali, A. Hassan, and A. Shamaa, "Neupogen and mesenchymal stem cells are the novel therapeutic agents in regeneration of induced endometrial fibrosis in experimental rats.", Bioscience reports, vol. 37, issue 5, 2017 Oct 31. Abstract

Endometrial fibrosis is the presence of intrauterine adhesions (IUAs) after any uterine surgery or curettage and it results in infertility and recurrent pregnancy loss. We evaluated the role of human mesenchymal stem cells (hMSCs) as a therapeutic agent of endometrial fibrosis. We also compared the effect of MSCs with the effect of estrogen and neupogen either each alone or as a combined therapy with MSCs. This experimental study was performed on 84 albino rats which were divided into seven groups (=12 rats/group) as follows, 1: normal control rats, 2: induced fibrosis, 3: induced fibrosis that received oral estrogen, 4: induced fibrosis that received hMSCs, 5: induced fibrosis that received hMSCs and estrogen, 6: induced fibrosis that received neupogen, and 7: induced fibrosis that received hMSCs and neupogen. The extent of fibrosis, vascularization, and inflammation were evaluated by; qRT-PCR for interleukin 1 (IL-1), interleukin 6 (IL-6), TNF, vascular endothelial growth factor (VEGF), transforming growth factor-β (TGF-β), and RUNX; ELISA for connective tissue growth factor (CTGF); Western blotting for collagen-I; immunohistochemistry examination for VEGF and RUNX-2; and histopathological assessment. In therapeutic groups either by hMSCs alone or combined with estrogen or neupogen; fibrosis and inflammation (IL-1, IL-6, TNF, TGF-β, RUNX, CTGF, and collagen-I) were significantly decreased but vascularization (VEGF) was significantly increased (<0.05) compared with induced fibrosis group. The most significant result was obtained in fibrosis that received combined therapy of hMSCs and neupogen (=0.000). Stem cells and neupogen are a highly effective alternative regenerative agents in endometrial fibrosis.

Abuowarda1, M., M. Amer, A. Shamaa, A. A. G. Shehab3, and M. Hassan, "A preliminary study of endoscopic diagnosis of gastric ulcer in Egyptian donkeys (Equus asinus) parasitized by Gasterophilus intestinalis (Diptera: Oestridae) ", Bulgarian Journal of Veterinary Medicine, issue https://doi.org/10.47278/journal.ijvs. 2021, 2020.
Shamaa, A., D. E. Hanafy2, T. F. Khalifa, M. M. Salem, G. G. Shehab, N. M. Aly, and E. HASSAN, "Pressure-induced left ventricular hypertrophy in canine model of aortic stenosis using nylon tie", Acta Scientiarum. Biological Sciences, vol. 42, 2020.
El-Rahma, S. A. S., M. S. Amer, M. H. Hassan, H. M. Fahmy, and A. A. Shamaa, "Repair of experimentally induced femoral chondral defect in a rabbit model using Lyophilized growth promoting factor extracted from horse blood platelets (L-GFequina)", Injury, issue Ms. No. JINJ-D-21- accepted02200R1, 2022.
Samer, M., F. A. Torad, A. A. Shamaa, O. S. El-Tookhy, D. S. A. Fatah, L. A. Rashed, M. A. Hamid, S. M. Mahfouz, and D. M. Gharib, "Role of Endothelial Progenitor Cells in Management of Myocardial Infarction Following Total Coronary Occlusion in Dogs.", Research Journal of Pharmaceutical, Biological and Chemical Sciences, vol. 7, issue 3, pp. 1225-1237, 2016. endothelial_progenitor_cells.pdf
Hassan;, M. H., E. H.; O. E. -tookhyA. S. Ashraf A. Shamaa, D. S. Abdelfatah;, and G. G. Shehab, "Role of hepatocyte differentiated mesenchymal stem cells in treatment of experimentally induced liver cirrhosis.", Asian J. Anim. Sci., 10 (2): 120-130, 2016.
Soliman, A. S., M. S. Amer, A. A. Shamaa, D. Sabry, G. G. Shehab, and O. Hagag, "Using of Chitosan seeded with autologous undifferentiated Mesenchymal Stem Cells for Femoral Bone Defect Management in dog", Dogs. Research Journal of Pharmaceutical, Biological and Chemical Sciences (RJPBCS);, issue 6(4):1220-1231., 2015.
Conference Proceedings
Hafez, M., A. Moghny, and A. Shamaa, "Custom made Implant and Patient Specific instruments for dog knee replacement", CAOS 2017 , Canada, 2017.
Hafez, M., A. Moghny, and A. Shamaa, "PSI for Dog Knee Replacement.", 17TH ANNUAL MEETING OF THE INTERNATIONAL SOCIETY FOR COMPUTER ASSISTED ORTHOPAEDIC SURGERY, 2017.
Conference Paper
Ahmed, A. S., A. A. Shamaa, and E. A. Hassan, "Sternal cartilage autograft for repair of full-thickness articular cartilage defect: An experimental study on equine model. Part 2: Histopathological, histochemical and biochemical study", 2nd International Conference and Exhibition on Orthopedics & Rheumatology August 19-21, Embassy Suites, Las Vegas, USA, 2013.
S.Ahmed, A., A. A. Shamaa, and E. A. Hassan, "Sternal cartilage autograft for repair of full-thickness articular cartilage defect: An experimental study on equine model. Part 2: Histopathological, histochemical and biochemical study. ", 2nd International Conference and Exhibition on Orthopedics & Rheumatology August 19-21, Embassy Suites , Las Vegas, USA, 2013.
Ahmed, A. S., A. A. Shamaa, and E. A. Hassan, "Sternal cartilage autograft for repair of full-thickness articular cartilage defect: An experimental study on equine model.Part 1: Clinical and radiographic study. ", 2nd International Conference and Exhibition on Orthopedics & Rheumatology August 19-21, Embassy Suites, Las Vegas, USA, 2013.
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