Graphene-based Disposable Electrochemical Sensor for Chlorhexidine Determination
- Citation:
- Magdy, N., A. E. Sobaih, L. A. Hussein, and A. M. Mahmoud, "Graphene-based Disposable Electrochemical Sensor for Chlorhexidine Determination", ElectroanalysisElectroanalysis, vol. 35, issue 2: John Wiley & Sons, Ltd, pp. e202200119, 2023.
Abstract:
Abstract In this work, simple, reliable, eco-friendly, and quantitative electrochemical sensors were developed to detect chlorhexidine Digluconate (CHX) in a variety of dosage forms, including mouthwashes and intimate douches, as well as chlorhexidine in spiked human saliva. Without any sample pre-treatment or extraction processes, CHX was measured in colored aqueous formulations. Based on carbon screen-printed electrodes, two potentiometric sensors (sensors I and II), utilizing graphene nanocomposites (Gr-NC), were designed (SPEs). An ionophore, 2-hydroxypropyl-?-cyclodextrin, was doped into the Poly Vinyl Chloride (PVC) polymeric membrane to improve sensor selectivity.
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