Hantzsch reaction with bis-indole-2,3-diones: Synthesis of novel bis-spirocyclic oxindole incorporating acridine, dipyrazolo[3,4-b:4',3'-e]pyridine and pyrido[2,3-d:6,5-d']dipyrimidine

Citation:
Abdelmoniem, A. M., M. G. M. Abdelrahman, S. A. S. Ghozlan, A. H. M. Elwahy, and I. A. Abdelhamid, "Hantzsch reaction with bis-indole-2,3-diones: Synthesis of novel bis-spirocyclic oxindole incorporating acridine, dipyrazolo[3,4-b:4',3'-e]pyridine and pyrido[2,3-d:6,5-d']dipyrimidine", Synthetic Communications, vol. 51, issue 12: Taylor & Francis, pp. 1814 - 1824, 2021///.

Abstract:

One-pot three-component cyclo-condensation reaction of bis(indole-2,3-diones) with dimedone, 3-methyl-1H-pyrazol-5(4H)-one, or 6-aminouracil in boiling acetic acid afforded bis-spirocyclic oxindoles linked to acridine, dipyrazolo[3,4-b:4',3'-e]pyridine, and pyrido[2,3-d:6,5-d']dipyrimidine, respectively.

Notes:

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