Hantzsch reaction with 6-Aminouracil: Synthesis of novel tetrakis(6-Aminouracil-5-yl)methanes and bis(decahydropyrido[2,3-d:6,5-d']dipyrimidine-Tetraones) linked to aliphatic or aromatic cores via ether-Amide or ester-Amide linkages

Citation:
Abdelmoniem, A. M., A. M. Abdella, A. H. M. Elwahy, and I. A. Abdelhamid, "Hantzsch reaction with 6-Aminouracil: Synthesis of novel tetrakis(6-Aminouracil-5-yl)methanes and bis(decahydropyrido[2,3-d:6,5-d']dipyrimidine-Tetraones) linked to aliphatic or aromatic cores via ether-Amide or ester-Amide linkages", Arkivoc, vol. 2020, issue 8, pp. 136 - 149, 2020///.

Abstract:

One-pot three-component cyclo-condensation reaction of bis(aldehydes) containing ether-Amide or ester-Amide linkages with 6-Aminouracil in boiling acetic acid afforded tetrakis(6-Aminopyrimidine-2,4-diones) or bis(tetraoxodecahydropyrido[2,3-d:6,5-d']dipyrimidines) depending on the reaction conditions.

Notes:

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