Effects of the 1-N-(4-Amino-2S-hydroxybutyryl) and 6′-N-(2-Hydroxyethyl) Substituents on Ribosomal Selectivity, Cochleotoxicity, and Antibacterial Activity in the Sisomicin Class of Aminoglycoside Antibiotics

Citation:
Sonousi, A., V. A. Sarpe, M. Brilkova, J. Schacht, A. Vasella, E. C. Böttger, and D. Crich, "Effects of the 1-N-(4-Amino-2S-hydroxybutyryl) and 6′-N-(2-Hydroxyethyl) Substituents on Ribosomal Selectivity, Cochleotoxicity, and Antibacterial Activity in the Sisomicin Class of Aminoglycoside Antibiotics", ACS Infectious Diseases, vol. 4, issue 7: American Chemical Society, pp. 1114 - 1120, 2018.

Abstract:

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Notes:

doi: 10.1021/acsinfecdis.8b00052

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