Publications

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2023
Hagiga, A., M. Aly, M. Gumaa, A. R. Youssef, and T. Cubison, "Targeted muscle reinnervation in managing post-amputation related pain: A systematic review and meta-analysis", Pain Practice, vol. 23, issue 8, pp. 922-932, 2023.
2020
El-Agroudy, M. N., M. Gaber, D. Joseph, M. Ibrahim, M. Amin, D. Helmy, M. Hanafy, S. Hisham, M. I. Awad, A. R. Youssef, et al., "Assistive Exoskeleton Hand Glove", International Conference on Innovative Trends in Computer Engineering (ITCE), Aswan, Egypt, 8-9 Feb. 2020.
2014
Khairedin, A., khaled ayad, M. G. Bakry, A. R. Youssef, and G. Hosny, "Changes in Muscle Architecture With Various Exercises During Distraction Osteogenesis of Tibia", APTA NEXT Conference and Exposition, Charlott, North Carolina, USA, 2014.
Youssef, A. R., W. F. Hafez, khaled ayad, and E. S. B. Saweeres, "Mobilization and taping in treatment of shoulder impingement syndrome", APTA CSM, Las Vegas, Nevada, USA, 2014.
Hafez, W. F., A. R. Youssef, khaled ayad, and E. S. B. Saweeres, "Mobilization with Movement Combined With Taping Restores Shoulder Function and Mobility in Shoulder Impingement Syndrome", 15th EFORT Congress, London, UK, 2014.
2013
A., O., M. NF, A. R. Youssef, R. H., and B. AA., "Measurement of cranio-vertebral angle with electronic head posture instrument and head posture spinal curvature instrument: a reliability study", Physical Therapy: The future of the Treatment”: the 14th International scientific conference, Faculty of Physical Therapy, Cairo University, Egypt, 2013.
AO, A., A. R. Youssef, M. NF, R. H, and B. A, "The Role of Exercise in Preventing Forward Head Posture.", 9th International Deformity Correction Conference, Mena House Oberoi Hotel, Cairo, Egypt , 2013.
2011
Fortuna, R., M. A. Vaz, A. R. Youssef, D. Longino, and W. Herzog, "Changes in contractile properties of muscles receiving repeat injections of botulinum toxin (Botox).", Journal of biomechanics, vol. 44, issue 1, pp. 39-44, 2011 Jan 04. Abstract

Botulinum toxin type A (BTX-A) is a frequently used therapeutic tool to denervate muscles in the treatment of neuromuscular disorders. Although considered safe by the US Food and Drug Administration, BTX-A can produce adverse effects in target and non-target muscles. With an increased use of BTX-A for neuromuscular disorders, the effects of repeat injections of BTX-A on strength, muscle mass and structure need to be known. Therefore, the purpose of this study was to investigate the changes in strength, muscle mass and contractile material in New Zealand White (NZW) rabbits. Twenty NZW rabbits were divided into 4 groups: control and 1, 3 and 6 months of unilateral, repeat injections of BTX-A into the quadriceps femoris. Outcome measures included knee extensor torque, muscle mass and the percentage of contractile material in the quadriceps muscles of the target and non-injected contralateral hindlimbs. Strength in the injected muscles was reduced by 88%, 89% and 95% in the 1, 3 and 6 months BTX-A injected hindlimbs compared to controls. Muscle mass was reduced by 50%, 42% and 31% for the vastus lateralis (VL), rectus femoris (RF) and vastus medialis (VM), respectively, at 1 month, by 68%, 51% and 50% at 3 months and by 76%, 44% and 13% at 6 months. The percentage of contractile material was reduced for the 3 and 6 months animals to 80-64%, respectively, and was replaced primarily by fat. Similar, but less pronounced results were also observed for the quadriceps muscles of the contralateral hindlimbs, suggesting that repeat BTX-A injections cause muscle atrophy and loss of contractile tissue in target muscles and also in non-target muscles that are far removed from the injection site.

2010
Youssef, A. R., L. D, S. E, S. R, L. T, and W. Herzog, "Cartilage Degeneration in Different Models of Osteoarthritis in the New Zealand Rabbit", 11th Alberta Biomedical Engineering conference, Banff, Alberta, Canada, 2010.
Youssef, A. R., T. Leonard, and W. Herzog, "Effects of Hind Limb Muscle Weakness on Tibial Cartilage Degeneration in Rabbits", CSB/SCB 2010, Queen’s University, Kingston, 2010.
Youssef, A. R., L. D, S. R, L. T, and W. Herzog, "Exercising Weak Muscles Causes Selective Degeneration of Knee Cartilage", 56th annual meeting of the Orthopaedic Research Society, New Orleans, USA, 2010.
R, F., V. M, L. D, A. R. Youssef, and W. Herzog, "Morphological changes in contractile properties of muscles subjected to repeat injections of botulinum toxin (Botox).", Journal of Biomechanics, vol. 44, issue 1, pp. 39-40, 2010.
2009
Youssef, A. R., S. R, L. T, and W. Herzog, "Effects of Hind-Limb Muscle Weakness on Knee Osteoarthritis in Rabbits", Proceedings of the 10th Alberta Biomedical Engineering conference, Banff, Alberta, Canada, 2009.
Youssef, A. R., S. R, L. T, and W. Herzog, "Effects of Multiple-group Muscle weakness on the Retro-patellar Cartilage in rabbits", ASB conference, Penn State University, 2009.
Herzog, W., B. D, and A. R. Youssef, "Joint Mechanics in Osteoarthritis Osteoarthritis Joint Pain", pain in osteoarthritis, new jersey, Wiley-Blackwell, 2009.
R, F., V. M, L. D, A. R. Youssef, and W. Herzog, "Morphological changes in contractile properties of muscles subjected to repeat injections of botulinum toxin (Botox)", Proceedings of the 10th Alberta Biomedical Engineering conference, Banff, Alberta, Canada, 2009.
Youssef, A. R., S. R, L. T, and W. Herzog, "Muscle Weakness Causes Joint Degenration in Rabbits", Osteoarthritis Cartilage, vol. 17, pp. 1228-35, 2009.
2008
Youssef, A. R., S. R, L. T, and W. Herzog, "Muscle Weakness Causes Joint Degenration in Rabbits", The 16th Congress of the European Society of Biomechanics, Lucerne, Switzerland, 2008.
Youssef, A. R., S. R, L. T, and W. Herzog, "Muscle Weakness Causes Joint Degenration in Rabbits", The 54th annual meeting of the Orthopaedic Research Society, San francisco, USA, 2008.
Youssef, A. R., S. R, and W. Herzog, "Spontaneous Arthritis in Rabbit Is Not Aggravated by Increase in Physical Activity", Proceedings of the 9th Alberta Biomedical Engineering conference, Banff, Alberta, Canada, pp. 23, 2008.
2007
Youssef, A. R., S. R, L. T, and W. Herzog, "Muscle weakness Causes Joint Degenration in Rabbits", Proceedings of the 8th Alberta Biomedical Engineering conference, Banff, Alberta, Canada, 2007.
2002
Youssef, A. R., H. A. H., I. M. M., D. M. M, and H. G. A., "Effects of Early Closed Kinetic Chain Exercises on the Rate of Callus Formation during Distraction Osteogenesis by Ilizarov's Method", European Federation Of National Associations of Orthopaedics and Traumatology proceedings, Lisbon, Portugal, 2002.