Publications

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2022
Elshemy, H. A. H., M. A. Zaki, A. M. Mahmoud, S. I. Khan, A. G. Chittiboyina, and A. M. Kamal, "Development of potential anticancer agents and apoptotic inducers based on 4-aryl-4H chromene scaffold: Design, synthesis, biological evaluation and insight on their proliferation inhibition mechanism", Bioorganic Chemistry, vol. 118: Academic Press, pp. 105475, 2022. Abstract
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Ezzat, S. M., H. E. S. Teba, I. G. Shahin, A. M. Hafez, A. M. Kamal, and N. M. Aborehab, "development of semisynthetic apoptosis inducing agents based on natural phenolic acids scaffold: design, synthesis and invitro bological evaluation", molecules, vol. 27, no. 19, pp. 6724, 2022. Abstract
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2021
Aziz, M. W., A. M. Kamal, K. O. Mohamed, and A. A. Elgendy, "Design, synthesis and assessment of new series of quinazolinone derivatives as EGFR inhibitors along with their cytotoxic evaluation against MCF7 and A549 cancer cell lines", Bioorganic & medicinal chemistry letters, vol. 41: Pergamon, pp. 127987, 2021. Abstract
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2020
Shaaban, M. A., A. M. Kamal, S. I. Faggal, N. A. Farag, N. M. Aborehab, A. E. Elsahar, and K. O. Mohamed, "Design, synthesis, and biological evaluation of new pyrazoloquinazoline derivatives as dual COX-2/5-LOX inhibitors", Archiv der Pharmazie, vol. 353, no. 11, pp. 2000027, 2020. Abstract
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Shabaan;, M. A., S. I. Faggal;, A. E. Elsahar;, N. M. Aborehab, and KhaledO.Mohamed, "Design, synthesis, and biological evaluation of new pyrazoloquinazoline derivatives as dual COX‐2/5‐LOX inhibitors", Arch Pharm Chem. Life Sci., vol. 353, issue 11, pp. 1-17, 2020.
Khalil, O. M., A. M. Kamal, S. Bua, H. E. S. Teba, Y. M. Nissan, and C. T. Supuran, "Pyrrolo and pyrrolopyrimidine sulfonamides act as cytotoxic agents in hypoxia via inhibition of transmembrane carbonic anhydrases", European Journal of Medicinal Chemistry, vol. 188: Elsevier Masson, pp. 112021, 2020. Abstract
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Supuran, C. T., Y. M. Nissan, H. El Sayed Teba, S. Bua, A. M. Kamal, and O. M. Khalil, Pyrrolo and pyrrolopyrimidine sulfonamides act as cytotoxic agents in hypoxia via inhibition of transmembrane carbonic anhydrases, : Elsevier Masson SAS, 2020. Abstract
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Khalil, O. M., S. Bua, H. E. S. Teba, Y. M. Nissan, and C. T. Supuran, "Pyrrolo and pyrrolopyrimidine sulfonamides act as cytotoxic agents in hypoxia via inhibition of transmembrane carbonic anhydrases,", European Journal of Medicinal Chemistry , vol. 188 , pp. 112021, 2020.
Shabaan, M. A., A. M. Kamal, S. I. Faggal, A. E. Elsahar, and K. O. Mohamed, "Synthesis and biological evaluation of pyrazolone analogues as potential anti-inflammatory agents targeting cyclooxygenases and 5-lipoxygenase", Archiv der Pharmazie, vol. 353, no. 4, pp. 1900308, 2020. Abstract
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Shabaan;, M. A., S. I. Faggal;, A. E. Elsahar;, and KhaledO.Mohamed, "Synthesis and biological evaluation of pyrazolone analogues as potential anti‐inflammatory agents targeting cyclooxygenases and 5‐lipoxygenase. ", Arch Pharm Chem. Life Sci., vol. 353, issue 4, pp. 1-15, 2020.
Al-Ghorafi, M. A. - H., J. H. Abdullah, T. A. A. Yahya, and Shada H. Yassin, "Synthesis and Evaluation of Anticancer Activity of Some New Schiff Bases of Amino-Thiophene Derivatives,", EJPMR, , vol. 7 , issue (1), pp. 111-115, 2020.
2019
Al-Ghorafi, M. A. - H., J. H. Abdullah, T. A. A. Yahya, and Shada H. Yassin, "DESIGN, Synthesis, Molecular Docking and Biological Evaluation of Some New Thiophene Derivatives as Anti-Cancer Agents", EJPMR, , vol. 6, issue (12), pp. 160-167, 2019.
Mghwary, A. E. - S., E. M. Gedawy, and S. M. Abuel-Maaty, "Novel thienopyrimidine derivatives as dual EGFR and VEGFR-2 inhibitors: design, synthesis, anticancer activity and effect on cell cycle profile", J. Enzyme Inhibition and Medicinal Chemistry,, vol. 34, pp. 838–852, 2019.
Mghwary, A. E. - S., E. M. Gedawy, A. M. Kamal, and S. M. Abuel-Maaty, "Novel thienopyrimidine derivatives as dual EGFR and VEGFR-2 inhibitors: design, synthesis, anticancer activity and effect on cell cycle profile", Journal of enzyme inhibition and medicinal chemistry, vol. 34, no. 1: Taylor & Francis, pp. 838–852, 2019. Abstract
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2018
Kandeel, M. M., A. M. Kamal, B. H. Naguib, and M. S. A. Hassan, "Design, Synthesis, Cytotoxic Activity and Apoptosis-inducing Action of Novel Cinnoline Derivatives as Anticancer Agents", Anticancer Agents in Medicinal Chemistry, vol. 18, pp. 1208-1217, 2018.
a c Manal M. Kandeelb, Aliaa M. Kamal a*, B. N. M. H. H. S. A., "Design, Synthesis, Cytotoxic Activity and Apoptosis-inducing Action of Novel Cinnoline Derivatives as Anticancer Agents.", Anticancer agents in medicinal chemistry, vol. 18, 2018. Abstract
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Zhang, N., Y. Li, Z. Chen, and W. Qin, "Direct Preparation of Indole Hemiaminals through Organocatalytic Nucleophilic Addition of Indole to Aldehydes", Synthesis, vol. 50, no. 20: {\copyright} Georg Thieme Verlag, pp. 4063–4070, 2018. Abstract
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2017
Amal, K., and A. M., "Design, synthesis and cytotoxic activity of certain novel chalcone analogous compounds", European Journal of Medicinal Chemistry, vol. 126, pp. 52-60, 2017. 1-s2.0-s0223523416308625-main.pdf
El-Meligie, S., A. T. Taher, A. M. Kamal, and A. Youssef, "Design, synthesis and cytotoxic activity of certain novel chalcone analogous compounds", European journal of medicinal chemistry, vol. 126: Elsevier Masson, pp. 52–60, 2017. Abstract
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2016
El-Ansary, A. K., and A. M. Kamal, "Design, Synthesis and Biological Evaluation of Some 5-Arylthieno[2,3-d]- pyrimidines as Potential Anti-cancer Agents", chemical pharmaceutical buiietin, vol. 64, pp. 1172-1180, 2016.
Shaaban, M. A. - E., and A. M. Kamal, "Synthesis, characterisation and biological screening of some 2-substituted benzimidazole derivatives as potential anticancer agents", journal of chemical research, vol. 40, pp. 228-234, 2016.
El-Ansary, A. K., A. M. Kamal, and M. A. - H. Al-Ghorafi, "Design, Synthesis and Biological Evaluation of Some 5-Arylthieno [2, 3-d] pyrimidines as potential anti-cancer agents", Chemical and Pharmaceutical Bulletin, vol. 64, no. 8: The Pharmaceutical Society of Japan, pp. 1172–1180, 2016. Abstract
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Shaaban, M. A. - E., A. M. Kamal, and H. E. - S. Teba, "Synthesis, characterisation and biological screening of some 2-substituted benzimidazole derivatives as potential anticancer agents", Journal of Chemical Research, vol. 40, no. 4: SAGE Publications Sage UK: London, England, pp. 228–234, 2016. Abstract
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Mohammed Abed-Elrahman Shaabana, A. M. K. *a, and H. E. - Sayed Tebab, "Synthesis, characterization and biological screening of some 2-substituted benzimidazole derivatives as potential anticancer agents.", CHEMICAL RESEARCH, vol. 40, pp. 228–234, 2016. Abstract
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2015
, "Design, Synthesis, and Antitumor Activity of Novel 5-Pyridyl-1,3,4oxadiazole Derivatives against the Breast Cancer Cell Line MCF-7", biological and pharmaceutical bulletin-japan, vol. 38, issue 5, pp. 763-773, 2015.