Publications

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2008
Maged, A. M., M. M. AbdElnabi, and A. H. Hussein, "The effect of hormonal supplementation in clomiphene citrate stimulated cycles in women with unexplained infertility undergoing IUI", The effect of hormonal supplementation in clomiphene citrate stimulated cycles in women with unexplained infertility undergoing IUI, vol. 29, issue 1, pp. 547-558, 2008.
2010
El-Khayat, W., A. Maged, and H. Omar, " A comparative study between isosorbide mononitrate (IMN) versus misoprostol prior to hysteroscopy ", Middle East Fertility Society Journal, vol. 15, issue 4, pp. 278-280, 2010.
2011
Mohamed, A. M. M., W. S. M. El-Sherbiny, and W. A. I. Mostafa, " Combined contraceptive ring versus combined oral contraceptive (30-μg ethinylestradiol and 3-mg drospirenone)", International journal of gynaecology and obstetrics, vol. 114, issue 2, pp. 145-8, 2011.
Rashwan, A. S., H. M. Gaffar, and A. M. Maged, "Comparative Study Between Continuous Use of Oxytocin Infusion Throughout The Active Phase of Labor Versus its Discontinuation and its Effect on The Course of Labor", The medical journal of Cairo university, vol. 79, issue 2, pp. 121-125, 2011.
Maged, A. M., G. A. F. A. Moety, and A. A. Abdelrazik, "Comparative study between three different protocols for prevention of hypertensive disorders associating pregnancy", The medical journal of Cairo University , vol. 79, issue 1, pp. 429-434, 2011.
elkader Abohamila, F. A., A. M. Maged, and I. Aboulfoutoh, "Progesterone supplementation is just enough for luteal phase support in ICSI cycles", Kasr Al-Aini Journal of Obstetrics and Gynecology , vol. 2, issue 1, pp. 14-19, 2011.
Eldin, D. S., A. M. Maged, M. M. Abdelnabi, and M. Shata, "“Antral follicular count, ovarian volume and antimullerian hormone in the prediction of cycle cancellation and poor response in women undergoing controlled ovarian stimulation”", The medical journal of Cairo University , vol. 79, issue 2, pp. 243-253, 2011.
2012
Maged, A. M., H. Gaffar, and W. A. I. Mostafa, "Role of transvaginal ultrasound in detection of retained products of conception after abortion", Saudi journal of health science, vol. 1, issue 3, pp. 151-155, 2012. us_abortion_saudia.pdf
2013
Maged, A. M., and W. A. I. Mostafa, "Biochemical and ultrasonographic predictors of outcome in threatened abortion", Middle East Fertility Society Journal , vol. 18, issue 3, pp. 177–181, 2013.
2014
Maged, A. M., G. A. Fattah, W. A. I. Mostafa, and D. Ahmed, "Comparative study between different biomarkers for early prediction of gestational diabetes mellitus", The journal of maternal-fetal & neonatal medicine, vol. 27, issue 11, pp. 1108–1112, 2014.
Maged, A. M., A. Abdelhafez, W. A. I. Mostafa, and W. Elsherbiny, "Fetal middle cerebral and umbilical artery Doppler after 40 weeks gestational age.", The journal of maternal-fetal & neonatal medicine, vol. 27, issue 18, pp. 1880–1885, 2014.
Maged, A. M., A. Abdelmoneim, W. Said, and A. I. walaa mostafa, "Measuring the rate of fetal urine production using three-dimensional ultrasound during normal pregnancy and pregnancy-associated diabetes", The journal of maternal-fetal & neonatal medicine, vol. 27, issue 17, pp. 1790–1794, 2014.
Maged, A. M., A. Abdelhafez, W. Al Mostafa, and W. Elsherbiny, "Fetal middle cerebral and umbilical artery Doppler after 40 weeks gestational age.", The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, vol. 27, issue 18, pp. 1880-5, 2014 Dec. Abstract

OBJECTIVE: To determine the value of fetal Doppler indices named middle cerebral artery (MCA)-PI, umbilical artery (UA)-PI and MCA-PI/UA-PI ratio, and amniotic fluid volume assessment in pregnancies 280-294 d and their correlation with the mode of delivery and perinatal outcome.

STUDY DESIGN: Prospective observational study conducted on 100 whose gestational age (GA) from 40 to 42 weeks. MCA and UA Doppler and MCA-PI/UA-PI ratio, amniotic fluid volume (AFV) were assessed. They were divided into two groups based on the presence or absence of adverse perinatal outcome.

RESULTS: Women with adverse perinatal outcome showed lower MCA-PI (0.92 versus 1.29), MCA-PI:UA-PI ratio (1.04 versus 1.83), lower gestational age when assessed by ultrasound (37.82 versus 39.48 weeks), lower neonatal birth weight (2705 versus 3108 g), fetal biophysical profile (BPP) (4.55 versus 7.21) when compared to women with normal perinatal outcome. They also had higher cases with oligohydramnios (34 versus 5), and higher UA-PI (0.89 versus 0.72).

CONCLUSION: Women with adverse neonatal outcome had higher UA-PI and lower MCA-PI, MCA-PI:UA-PI ratio, GA (by US), AFV, BPP, estimated fetal weight, neonatal birth weight when compared to those with normal perinatal outcome. Women with adverse neonatal outcome had a higher rate of cesarean section mostly due to fetal distress and induced VD due to oligohydraminos compared to the normal outcome group.

Maged, A. M., G. A. F. Moety, W. A. Mostafa, and D. A. Hamed, "Comparative study between different biomarkers for early prediction of gestational diabetes mellitus.", The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, vol. 27, issue 11, pp. 1108-12, 2014 Jul. Abstract

OBJECTIVE: To study various biomarkers in prediction of gestational diabetes mellitus (GDM).

PATIENTS AND METHODS: Prospective observational study included 400 pregnant women. Maternal serum sex hormone binding globulin (SHBG), high-sensitive C-reactive protein (hs-CRP), uric acid, creatinine and albumin were measured before 15 weeks of gestation. Patients were followed-up for development of GDM.

RESULTS: A total of 269 women were eligible for analysis. GDM complicated 27 (10.03%) of pregnancies. Hs-CRP levels were significantly higher and SHBG levels were significantly lower among women who subsequently developed GDM compared with normoglycemics. Uric acid, albumin and creatinine levels were not significantly different between both groups. For prediction of GDM, hs-CRP at a cutoff value of 2.55 mg/l showed a sensitivity and a specificity of 89% and 55%, respectively. SHBG at a cutoff value of 211.5 nmol/l showed a sensitivity and a specificity of 85% and 37%, respectively. Low SHBG with high hs-CRP predicted GDM with a sensitivity and specificity of 74.07% and 75.62%, respectively with an overall accuracy of 75.46%.

CONCLUSION: Hs-CRP and SHBG are important early predictors of GDM. Adding SHBG to hs-CRP improves specificity and serves good overall accuracy. Uric acid, creatinine and albumin have no role in GDM prediction.

Maged, A. M., A. Abdelmoneim, W. Said, and W. A. I. Mostafa, "Measuring the rate of fetal urine production using three-dimensional ultrasound during normal pregnancy and pregnancy-associated diabetes.", The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, vol. 27, issue 17, pp. 1790-4, 2014 Nov. Abstract

OBJECTIVE: To establish a nomogram of fetal urine production according to gestational age as a predictor for fetal well-being in normal and diabetic women.

STUDY DESIGN: Prospective observational study included 180 pregnant women classified into two groups: Group I (120 women) without any medical complications and Group II (60 women) with gestational diabetes mellitus (GDM). The fetal bladder is measured by the virtual organ computer-aided analysis VOCAL 3D ultrasound scanner.

RESULTS: There was a significant positive correlation between gestational age and fetal urine production rate (UPR) (the mean UPR rate in normal pregnancy at 25, 30, 35, 40 weeks were 12.3, 14.38, 56.13 and 90.73 ml/h, respectively). There was no significant difference regarding UPR ml/h between women with normal pregnancy and those with controlled GDM (p = 0.9). There was a statistically significant difference regarding UPR ml/h between women with normal pregnancy and those with uncontrolled GDM (p = 0.012) and a statistically significant difference between women with controlled GDM and those with uncontrolled GDM (p = 0.03).

CONCLUSION: Fetal UPR is considered to be more reliable as an assessment method for fetal well-being and shows significant increase in patients with uncontrolled gestational DM.

2015
Maged, A. M., A. H. Gebril, and A. Abdelhafez, "2D and 3D ultrasound assessment of cesarean section scars and its correlation to intraoperative findings", Uterus & Ovary, vol. 2, issue e919, pp. 1-7, 2015. 919-5321-2-pb.pdf
Maged, A. M., H. Elsawah, A. Abdelhafez, A. Bakry, and W. A. I. Mostafa, "The adjuvant effect of metformine and N-acetylcysteine to clomiphene citrate in induction of ovulation in patients with Polycystic Ovary Syndrome", Gynecological Endocrinology, vol. 31, issue 8, pp. 635–638, 2015. metformine_nac_final.pdf
Maged, A. M., A. M. Nada, F. A. Abohamila, A. T. Hashim, W. A. I. Mostafa, and A. R. Elzayat, "Delayed start versus conventional GnRH antagonist protocol in poor responders pretreated by estradiol in luteal phase: A randomized controlled trial", reproductive sciences, vol. 22, issue 12, pp. 1627-31, 2015. delayed_start_gnrh.pdf
Maged, A. M., M. Elsherbini, W. Ramadan, R. Elkomy, O. Helal, D. Hatem, M. Fouad, and H. Gaafar, "Periconceptional risk factors of spina bifida among Egyptian population: a case–control study", The Journal of Maternal-Fetal & Neonatal Medicine, 2015. spina_bifida.pdf
Maged, A. M., O. Helal, M. M. Elsherbini, M. M. Eid, R. O. Elkomy, S. Dahab, and M. H. Elsissy, "A randomized placebo-controlled trial of preoperative tranexamic acid 3 among women undergoing elective cesarean delivery", International Journal of Gynecology and Obstetrics, vol. 131, issue 3, pp. 265-8, 2015.
Maged, A. M., M. N. Mohesen, A. Elhalwagy, and A. AbdElHafez, "Salivary progesterone and cervical length measurement as predictors of spontaneous preterm birth", The journal of maternal-fetal & neonatal medicine, vol. 28 , issue 10, pp. 1147–1151, 2015. salivary_p_final.pdf
Maged, A. M., N. S. Elnassery, M. A. Fouad, A. Abdelhafez, and W. A. I. Mostafa, "Third Trimester Uterine Artery Doppler Measurement in Severe Pre eclampsia Patients and Maternal Postpartum Outcome", International journal of gynecology and obstetrics, vol. 131, issue (2015), pp. 49–53, 2015. doppler_in_pih_final.pdf
Maged, A. M., H. Elsawah, A. Abdelhafez, A. Bakry, and W. A. I. Mostafa, "The adjuvant effect of metformin and N-acetylcysteine to clomiphene citrate in induction of ovulation in patients with Polycystic Ovary Syndrome.", Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, vol. 31, issue 8, pp. 635-8, 2015. Abstract

OBJECTIVES: To assess the adjuvant effect of metformin and N-acetylcysteine (NAC) to clomiphene citrate (CC) in induction of ovulation in Polycystic Ovary Syndrome (PCOS) patients.

STUDY DESIGN: 120 women with PCOS were randomly divided into three equal groups: group I received CC only, group II received CC plus NAC and group III received CC plus metformin.

RESULTS: There was a significant difference between group II and other two groups regarding average number of ovulatory follicles >18 mm (2.25 versus 1.75 and 1.89, respectively), but no significant difference between the three study groups regarding number of intermediate follicles 14-18 mm (4, 10 and 4, respectively). There was no significant difference between the three study groups regarding occurrence and laterality of ovulation, pregnancy rate per cycle but a significant difference between group II and other two groups regarding pregnancy rate per patient (20% versus 10% and 10%, respectively, p value 0.05). There was a highly statistically significant difference between group II and other two groups regarding peak endometrial thickness (7.3 ± 1.1 versus 5.4 ± 0.6 and 5.3 ± 0.6, respectively).

CONCLUSIONS: NAC as an adjuvant to CC for induction of ovulation improves ovulation and pregnancy rates in PCOS patients with beneficial impacts on endometrial thickness.

Maged, A. M., H. Elsawah, A. Abdelhafez, A. Bakry, and W. A. I. Mostafa, "The adjuvant effect of metformin and N-acetylcysteine to clomiphene citrate in induction of ovulation in patients with Polycystic Ovary Syndrome.", Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, pp. 1-4, 2015 Aug 04. Abstract

OBJECTIVES: To assess the adjuvant effect of metformin and N-acetylcysteine (NAC) to clomiphene citrate (CC) in induction of ovulation in Polycystic Ovary Syndrome (PCOS) patients.

STUDY DESIGN: 120 women with PCOS were randomly divided into three equal groups: group I received CC only, group II received CC plus NAC and group III received CC plus metformin.

RESULTS: There was a significant difference between group II and other two groups regarding average number of ovulatory follicles >18 mm (2.25 versus 1.75 and 1.89, respectively), but no significant difference between the three study groups regarding number of intermediate follicles 14-18 mm (4, 10 and 4, respectively). There was no significant difference between the three study groups regarding occurrence and laterality of ovulation, pregnancy rate per cycle but a significant difference between group II and other two groups regarding pregnancy rate per patient (20% versus 10% and 10%, respectively, p value 0.05). There was a highly statistically significant difference between group II and other two groups regarding peak endometrial thickness (7.3 ± 1.1 versus 5.4 ± 0.6 and 5.3 ± 0.6, respectively).

CONCLUSIONS: NAC as an adjuvant to CC for induction of ovulation improves ovulation and pregnancy rates in PCOS patients with beneficial impacts on endometrial thickness.

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