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A
elkader Abohamila, F. A., A. M. Maged, and I. Aboulfoutoh, "Progesterone supplementation is just enough for luteal phase support in ICSI cycles", Kasr Al-Aini Journal of Obstetrics and Gynecology , vol. 2, issue 1, pp. 14-19, 2011.
Ahmed Mohamed Maged1, 5, A. H. Abbassy2, H. R. S. Sakr3, H. Elsawah1, H. Wagih1, A. I. Ogila1, and A. Kotb4, "Effect of swimming exercise on premenstrual syndrome", Archives of Gynecology and Obstetrics, vol. 297, issue 1, pp. 951-959, 2018. swimming_final.pdf
E
El-Demiry, N. M., A. M. Maged, H. M. Gaafar, S. Elanwary, A. Shaltout, S. Ibrahim, H. M. El-Didy, and M. M. Elsherbini, "The value of fetal Doppler indices as predictors of perinatal outcome in women with preeclampsia with severe features", Hypertension in Pregnancy, vol. 39, issue 2, pp. 95-102, 2020.
El-Khayat, W., A. Maged, and H. Omar, " A comparative study between isosorbide mononitrate (IMN) versus misoprostol prior to hysteroscopy ", Middle East Fertility Society Journal, vol. 15, issue 4, pp. 278-280, 2010.
El-Sherbini, M. M., A. M. Maged, O. M. Helal, M. O. Awad, S. A. El-Attar, J. A. Sadek, R. Elkomy, and M. A. Dawoud, "A comparative study between preoperative rectal misoprostol and intraoperative intrauterine administration in the reduction of blood loss during and after cesarean delivery: A randomized controlled trial", International journal of Gynecology and obstetrics, vol. 153, pp. 113-118, 2021. preoperative_misoprostol.pdf
Eldin, D. S., A. M. Maged, M. M. Abdelnabi, and M. Shata, "“Antral follicular count, ovarian volume and antimullerian hormone in the prediction of cycle cancellation and poor response in women undergoing controlled ovarian stimulation”", The medical journal of Cairo University , vol. 79, issue 2, pp. 243-253, 2011.
H
Hassan, E. S., A. Maged, amal Kotb, M. Fouad, N. El-Nassery, and W. M. Kamal, "Effect of laser acupuncture on pain and density of bone in osteoporotic postmenopausal women: a randomized controlled trial", Menopause, vol. 30, issue 5, pp. 545-550, 2023.
Hosny, M., A. Maged, A. Reda, A. Abdelmeged, H. Hassan, and M. Kamal, "Obstetric venous thromboembolism: a one-year prospective study in a tertiary hospital in Egypt", The journal of Maternal fetal and Neonatal medicine, vol. 35, issue 14, pp. 2642-47, 2022.
M
Maged, A. M., O. M. Helal, M. M. Elsherbini, M. M. Eid, R. O. Elkomy, S. Dahab, and M. H. Elsissy, "A randomized placebo-controlled trial of preoperative tranexamic acid among women undergoing elective cesarean delivery.", International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, vol. 131, issue 3, pp. 265-8, 2015 Dec. Abstract

OBJECTIVE: To study the efficacy and safety of preoperative intravenous tranexamic acid to reduce blood loss during and after elective lower-segment cesarean delivery.

METHODS: A single-blind, randomized placebo-controlled study was undertaken of women undergoing elective lower-segment cesarean delivery of a full-term singleton pregnancy at a center in Cairo, Egypt, between November 2013 and November 2014. Patients were randomly assigned (1:1) using computer-generated random numbers to receive either 1g tranexamic acid or 5% glucose 15 minutes before surgery. Preoperative and postoperative complete blood count, hematocrit values, and maternal weight were used to calculate the estimated blood loss (EBL) during cesarean, which was the primary outcome. Analyses included women who received their assigned treatment, whose surgery was 90 minutes or less, and who completed follow-up.

RESULTS: Analyses included 100 women in each group. Mean EBL was significantly higher in the placebo group (700.3 ± 143.9 mL) than in the tranexamic acid group (459.4 ±7 5.4 mL; P<0.001). Only six women, all in the placebo group, experienced an EBL of more than 1000 mL. There were no reports of thromboembolic events up to 4 weeks postoperatively.

CONCLUSION: Preoperative administration of tranexamic acid safely reduces blood loss during elective lower-segment cesarean delivery. Australian New Zealand Clinical Trials Registry:ACTRN12615000312549.

Maged, A. M., H. nabil, A. S. Dieb, A. Essam, S. Ibrahim, W. Deeb, and R. M. Fahmy, "Prediction of metaphase II oocytes according to different levels of serum AMH in poor responders using the antagonist protocol during ICSI: a cohort study", Gynecological Endocrinology, vol. 36, issue 8, pp. 728-733, 2020.
Maged, A. M., A. G. M. A. G. Hassan, and N. A. Shehata, "Carbetocin versus oxytocin for prevention of postpartum hemorrhage after vaginal delivery in high risk women", J Matern Fetal Neonatal Med, vol. 29, issue 4, pp. 532-536., 2016. carbetocin.pdf
Maged, A. M., H. Torky, M. A. Fouad, S. H. Gad Allah, N. M. Waked, A. S. Gayed, and A. K. Salem, "Role of antioxidants in gestational diabetes mellitus and relation to fetal outcome: a randomized controlled trial", The journal of maternal-fetal & neonatal medicine, vol. 29, issue 24, pp. 4049–4054, 2016. 7_antioxidants.pdf
Maged, A. M., A. M. T. Hashem, S. H. Gad Allah, M. E. Mahy, W. A. I. Mostafa, and amal Kotb, "The effect of loading dose of magnesium sulfate on uterine, umbilical, and fetal middle cerebral arteries Doppler in women with severe preeclampsia: A case control study.", Hypertension in pregnancy, vol. 35, issue 1, pp. 91-9, 2016. Abstract

UNLABELLED: SYNOPSIS IV MgSO4 administration in women with severe preeclampsia resulted in a decrease in umbilical artery, uterine artery, and fetal middle cerebral artery Doppler indices.

OBJECTIVE: To evaluate Doppler parameters of the umbilical artery (UmA), uterine artery (UA), and fetal middle cerebral artery (MCA) before and after MgSO4 administration in women with severe preeclampsia.

METHODS: A case control study included 100 pregnant women with severe preeclampsia. Umbilical artery, uterine artery, and fetal middle cerebral artery Doppler were measured before and 20 minutes after intravenous administration of 6 g of magnesium sulfate.

RESULTS: There was a significant difference between maternal systolic blood pressure (173.20 ± 22.72 vs. 156.60 ± 19.18), diastolic blood pressure (109.60 ± 9.14 vs. 101.90 ± 10.05), and heart rate (80.52 ± 11.52 vs. 88.48 ± 12.08) before and after administration of MgSO4 in the studied patients (p value < 0.001). There was a significant difference between umbilical artery, middle cerebral artery, and uterine artery Doppler parameters before and after administration of MgSO4 in the studied patients (p value < 0.001). There was no significant difference between umbilical artery/middle cerebral artery with regard to RI and PI. However, there was significant difference with regard to the S/D ratio (p value < 0.001). The decrease in the values of Doppler parameters before and after administration of MgSO4 was more in the middle cerebral artery than in the umbilical artery.

CONCLUSION: Intravenous administration of magnesium sulfate in pregnant women with severe preeclampsia resulted in a decrease in umbilical artery, uterine artery, and fetal middle cerebral artery Doppler indices with reduced resistance to blood flow in these vessels.

Maged, A. M., H. Rashwan, M. Mahmoud, A. El-Mazny, M. Farouk, Doaa S. Belal, and H. M. Marie, "Effect of Prolonged GnRH Agonist Downregulation on ICSI Outcome in Patients With Endometriomas of Less Than 5 cm: A Randomized Controlled Trial", Reproductive Sciences, vol. 25, issue 10, pp. 1509-1514, 2018. gnrh_in_eo_final.pdf
Maged, A. M., M. Elsherbini, W. Ramadan, R. Elkomy, O. Hilal, D. Hatem, M. Fouad, and H. Gaafar, "Periconceptional risk factors of spina bifida among Egyptian population: a case–control study", Journal of maternal fetal and neonatal medicine, vol. 29, issue 14, pp. 2264–2267, 2016. 15_spina_bifida_final.pdf
Maged, A. M., G. Aid, N. Bassiouny, D. S. Eldin, S. Dahab, and N. K. Ghamry, "Association of biochemical markers with the severity of pre-eclampsia.", International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, vol. 136, issue 2, pp. 138-144, 2017 Feb. Abstract

OBJECTIVE: To assess the association between pre-eclampsia severity and biochemical and ultrasonography markers.

METHODS: A retrospective study was undertaken of women with severe pre-eclampsia (group 1, n=90), mild pre-eclampsia (group 2, n=90), or a normal pregnancy (group 3, n=90) who attended a hospital in Egypt in October 2013-April 2015. Associations between pre-eclampsia and biochemical, cardiotocography, and ultrasonography markers were investigated.

RESULTS: There were significant differences between the groups in C-reactive protein (331.44±112.38, 251.43±59.05, and 23.81±16.19 nmol/L; P≤0.05 for all), platelet count (113.40±36.72, 172.93±57.60, and 212.68±70.00×10(9) /L; P≤0.05 for group 1 comparisons), alanine transaminase (52.24±14.83, 38.34±13.12, and 23.11±6.92 U/L; P≤0.05 for group 1 comparisons), and serum uric acid (600.80±117.19, 481.83±118.97, and 243.89±53.54 μmol/L; P=0.050 for group 3 comparisons). Cardiotocography score was worse among women with severe pre-eclampsia than among those in the other two groups (P=0.039 for both comparisons). Biophysical profile score and umbilical artery resistance index differed by group (P≤0.05 for all). Middle cerebral artery resistance index was lower among women with severe pre-eclampsia (P≤0.05).

CONCLUSION: The levels of C-reactive protein, blood urea nitrogen, serum uric acid, and alanine transaminase, and the platelet count were linked with the presence and severity of pre-eclampsia.

Maged, A. M., A. E. - M. Ramzy, M. Aboulghar, S. G. H. Allah, A. H. Wahba, A. A. Y. ElKateb, and N. Hwedi, "3D ultrasound assessment of endometrial junctional zone anatomy as a predictor of the outcome of ICSI cycles", European Journal of Obstetrics & Gynecology and Reproductive Biology, vol. 212, issue 1, pp. 160-165, 2017. jz.pdf
Maged, A. M., A. M. Kamel, F. Abu-hamila, R. O. Elkomy, O. A. Ohida, S. M. Hassan, R. M. Fahmy, and W. Ramadan, "The measurement of endometrial volume and sub-endometrial vascularity to replace the traditional endometrial thickness as predictors of fertilization success.", Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, vol. 35, issue 11, pp. 949-954, 2019. Abstractthe_measurement_of_endometrial_volume_and_sub_endometrial_vascularity_to_replace_the_traditional_endometrial_thickness_as_predictors_of_in_vitro.pdf

To assess the value of endometrial thickness, volume, and sub-endometrial perfusion in women undergoing IVF. In 82 women candidate for ICSI, endometrial thickness and sub-endometrial perfusion were measured with a trans-vaginal 2 D ultrasound and 3 D power Doppler respectively on day of hCG trigger and Embryo transfer (ET). The primary outcome was the clinical pregnancy rate. Endometrial volume showing a statistically significant difference between pregnant and nonpregnant women (4.11 ± 1.19 vs. 3.4 ± 1.1  = .019) on day of triggering and at ET (4.02 ± 1.15 vs. 3.45 ± 0.90,  = .022). VFI was significantly higher in pregnant group at both days of triggering and ET (0.54 ± 0.48 vs. 0.33 ± 0.31 and 0.47 ± 0.22 vs. 0.34 ± 0.2,  = .02). At cutoff values of 3.265 and 2.95 cm3 (70 & 80% sensitivity, specificity 64.5 & 51.6%, a positive predictive value 38.9 & 34.8%, and negative predictive value 87.0 & 88.9%) to predict pregnancy on the day of hCG trigger & ET respectively. Cutoff value for Endometrial VFI on the day of ET was 0.674 (sensitivity of 70%, specificity of 80.6%, PPV 53.8%, and NPV 89.3%). Higher endometrial volume and VFI were associated with pregnancy.

Maged, A. M., M. N. Mohesen, A. Elhalwagy, and A. AbdElHafez, "Salivary progesterone and cervical length measurement as predictors of spontaneous preterm birth", The journal of maternal-fetal & neonatal medicine, vol. 28 , issue 10, pp. 1147–1151, 2015. salivary_p_final.pdf
Maged, A. M., O. Helal, M. M. Elsherbini, M. M. Eid, R. O. Elkomy, S. Dahab, and M. H. Elsissy, "A randomized placebo-controlled trial of preoperative tranexamic acid 3 among women undergoing elective cesarean delivery", International Journal of Gynecology and Obstetrics, vol. 131, issue 3, pp. 265-8, 2015.
Maged, A. M., D. S. Belal, H. M. Marie, H. Rashwan, S. Abdelaziz, A. A. Gabr, and A. R. Elzayat, "Prospective study of the effect of maternal body mass index on labor progress in nulliparous women in Egypt.", International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, vol. 139, issue 3, pp. 329-335, 2017 Dec. Abstract

OBJECTIVE: To evaluate the impact of maternal body mass index (BMI, calculated as weight in kilograms divided by the square of height in meters) on labor progress in nulliparous women.

METHODS: The present prospective cohort study enrolled primigravidae admitted to Kasr Al Ainy hospital, Cairo University, Egypt, during active labor between February 1, 2016, and February 28, 2017. Patients were classified into three equal groups using their BMI at admission: underweight (<18.5), normal weight (18.5-29.9), and obese (≥30). The primary outcome was the rate of cervical dilatation; secondary outcomes included the duration of the second stage of labor, neonatal delivery weight, and the mode of delivery.

RESULTS: Among the 600 primigravidae enrolled (200 in each group), significant differences were recorded in the rates of cervical dilatation (P<0.001), and the duration of the active labor phase (P<0.001) and the whole of labor (P<0.001); in the obese group, the cervical dilatation rate was lowest and the durations of the active phase of labor and the whole of labor were longer. The incidence of intrapartum cesarean delivery (P<0.001) and neonatal delivery weight (P<0.001) also differed between the groups; both were highest in the obese group.

CONCLUSIONS: Patterns in labor progress, including cervical dilatation rate and labor duration, differed among patients with different BMI. ClinicalTrials.gov: NCT02686073.

Maged, A. M., A. Abdelhafez, W. Al Mostafa, and W. Elsherbiny, "Fetal middle cerebral and umbilical artery Doppler after 40 weeks gestational age.", The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, vol. 27, issue 18, pp. 1880-5, 2014 Dec. Abstract

OBJECTIVE: To determine the value of fetal Doppler indices named middle cerebral artery (MCA)-PI, umbilical artery (UA)-PI and MCA-PI/UA-PI ratio, and amniotic fluid volume assessment in pregnancies 280-294 d and their correlation with the mode of delivery and perinatal outcome.

STUDY DESIGN: Prospective observational study conducted on 100 whose gestational age (GA) from 40 to 42 weeks. MCA and UA Doppler and MCA-PI/UA-PI ratio, amniotic fluid volume (AFV) were assessed. They were divided into two groups based on the presence or absence of adverse perinatal outcome.

RESULTS: Women with adverse perinatal outcome showed lower MCA-PI (0.92 versus 1.29), MCA-PI:UA-PI ratio (1.04 versus 1.83), lower gestational age when assessed by ultrasound (37.82 versus 39.48 weeks), lower neonatal birth weight (2705 versus 3108 g), fetal biophysical profile (BPP) (4.55 versus 7.21) when compared to women with normal perinatal outcome. They also had higher cases with oligohydramnios (34 versus 5), and higher UA-PI (0.89 versus 0.72).

CONCLUSION: Women with adverse neonatal outcome had higher UA-PI and lower MCA-PI, MCA-PI:UA-PI ratio, GA (by US), AFV, BPP, estimated fetal weight, neonatal birth weight when compared to those with normal perinatal outcome. Women with adverse neonatal outcome had a higher rate of cesarean section mostly due to fetal distress and induced VD due to oligohydraminos compared to the normal outcome group.

Maged, A. M., E. M. Soliman, A. A. Abdellatif, M. Nabil, O. I. Said, M. N. Mohesen, A. N. Raslan, and S. M. Y. Elbaradie, "Measurement of the fetal occiput-spine angle during the first stage of labor as predictor of the progress and outcome of labor", The Journal of Maternal-Fetal & Neonatal Medicine, vol. 32, issue 14, pp. 2332-2337, 2019. measurement_of_the_fetal_occiput_spine_angle_during_the_first_stage_of_labor_as_predictor_of_the_progress_and_outcome_of_labor.pdf
Maged, A. M., H. H. Kamel, A. S. Sanad, A. E. Mahram, A. A. AbdAllah, R. Elkhateeb, H. A. Bhaa, E. A. Hussein, A. Essam, and S. Ibrahim, "The value of amniopatch in pregnancies associated with spontaneous preterm premature rupture of fetal membranes: a randomized controlled trial", The Journal of Maternal-Fetal & Neonatal Medicine, vol. 34, issue 2, pp. 267-273, 2021. the_value_of_amniopatch_in_pregnancies_associated_with_spontaneous_preterm_premature_rupture_of_fetal_membranes_a_randomized_controlled_trial.pdf
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