Seasonal influence on miRNA expression dynamics of extracellular vesicles in equine follicular fluid

Citation:
Feugang, J. M., A. Gad, N. G. Menjivar, G. M. Ishak, S. Gebremedhn, M. O. Gastal, N. H. Dlamini, R. Prochazka, E. L. Gastal, and D. Tesfaye, "Seasonal influence on miRNA expression dynamics of extracellular vesicles in equine follicular fluid", Journal of Animal Science and Biotechnology, vol. 15, issue 1, pp. 137, 2024.

Abstract:

Ovarian follicular fluid (FF) is a dynamic environment that changes with the seasons, affecting follicle development, ovulation, and oocyte quality. Cells in the follicles release tiny particles called extracellular vesicles (EVs) containing vital regulatory molecules, such as microRNAs (miRNAs). These miRNAs are pivotal in facilitating communication within the follicles through diverse signaling and information transfer forms. EV-coupled miRNA signaling is implicated to be associated with ovarian function, follicle and oocyte growth and response to various environmental insults. Herein, we investigated how seasonal variations directly influence the ovulatory and anovulatory states of ovarian follicles and how are they associated with follicular fluid EV-coupled miRNA dynamics in horses.

Notes:

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