Ahmed Yehia Gad
Associate Professor of Animal Physiology
Faculty of Agriculture, Cairo Universty, 12613 Giza, Egypt (email)
Extracellular vesicle-microRNAs mediated response of bovine ovaries to seasonal environmental changes
- Citation:
- Gad, A., K. Joyce, N. G. Menjivar, D. Heredia, C. S. Rojas, D. Tesfaye, and A. Gonella-Diaza, "Extracellular vesicle-microRNAs mediated response of bovine ovaries to seasonal environmental changes", Journal of Ovarian Research, vol. 16, issue 1, pp. 101, 2023.
Abstract:
Among the various seasonal environmental changes, elevated ambient temperature during the summer season is a main cause of stress in dairy and beef cows, leading to impaired reproductive function and fertility. Follicular fluid extracellular vesicles (FF-EVs) play an important role in intrafollicular cellular communication by, in part, mediating the deleterious effects of heat stress (HS). Here we aimed to investigate the changes in FF-EV miRNA cargoes in beef cows in response to seasonal changes: summer (SUM) compared to the winter (WIN) season using high throughput sequencing of FF-EV-coupled miRNAs. In addition to their biological relevance, the potential mechanisms involved in the packaging and release of those miRNAs as a response to environmental HS were elucidated.
Notes:
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