@article {192151, title = {Surgical repair for persistent truncus arteriosus in neonates and older children.}, journal = {Journal of cardiothoracic surgery}, volume = {15}, year = {2020}, pages = {83}, abstract = {

OBJECTIVES: Persistent truncus arteriosus represents less than 3\% of all congenital heart defects. We aim to analyze mid-term outcomes after primary Truncus arteriosus repair at different ages and to identify the risk factors contributing to mortality and the need for intervention after surgical repair.

METHODS: This retrospective cohort study included 36 children, underwent repair of Truncus arteriosus in the period from January 2011 to December 2018 in two institutions. We recorded the clinical and echocardiographic data for the patients preoperatively, early postoperative, 6 months postoperative, then every year until their last documented follow-up appointment.

RESULTS: Thirty-six patients had truncus arteriosus repair during the study period. Thirty-one patients had open sternum post-repair, and two patients required extracorporeal membrane oxygenation. Bleeding occurred in 15 patients (41.67\%), and operative mortality occurred in 5 patients (14.7\%). Patients with truncus arteriosus type 2 (p~= 0.008) and 3 (p~= 0.001) and who were ventilated preoperatively (p~\< 0.001) had a longer hospital stay. Surgical re-intervention was required in 8 patients (22.86\%), and 11 patients (30.56\%) had catheter-based reintervention. Freedom from reintervention was 86\% at 1 year, 75\% at 2 years and 65\% at 3 years. Survival at 1 year was 81\% and at 3 years was 76\%. High postoperative inotropic score predicted mortality (p~= 0.013).

CONCLUSION: Repair of the truncus arteriosus can be performed safely with low morbidity and mortality, both in neonates, infants, and older children. Re-intervention is common, preferably through a transcatheter approach.

}, attachments = {https://scholar.cu.edu.eg/sites/default/files/adohain/files/truncus_artriosus.pdf}, author = {Alamri, Rawan M and Dohain, Ahmed M and Arafat, Amr A and Elmahrouk, Ahmed F and Ghunaim, Abdullah H and Elassal, Ahmed A and Jamjoom, Ahmed A and Al-Radi, Osman O} }