Visualizing and identifying the DNA methylation markers in breast cancer tumor subtypes

Citation:
Amin, I. I., A. E. Hassanien, Hesham A. Hefny, and S. K. Kassim, "Visualizing and identifying the DNA methylation markers in breast cancer tumor subtypes", The 5th International Conference on Innovations in Bio-Inspired Computing and Applications (Springer) IBICA2014, Ostrava, Czech Republic., 22-24 June, 2014.

Date Presented:

22-24 June

Abstract:

DNA methylation is an epigenetic mechanism that cells use to control
gene expression. DNA methylation has become one of the hottest topics in cancer
research, especially for abnormally hypermethylated tumor suppressor genes
or hypomethylaed oncogenes research. The analysis of DNA methylation data
determines the differential hypermethlated or hypomethylated genes that are candidate
to be cancer biomarkers. Visualization the DNA methylation status may
lead to discover new relationships between hypomethylated and hypermethylated
genes, therefore this paper applied a mathematical modelling theory called formal
concept analysis for visualizing DNA methylation status.

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