Alaa Tharwat, and A. E. Hassanien,
"Chaotic antlion algorithm for parameter optimization of support vector machine",
Applied Intelligence, vol. 48, issue 3, pp. 670–686, 2018.
AbstractSupport Vector Machine (SVM) is one of the well-known classifiers. SVM parameters such as kernel parameters and penalty parameter (C) significantly influence the classification accuracy. In this paper, a novel Chaotic Antlion Optimization (CALO) algorithm has been proposed to optimize the parameters of SVM classifier, so that the classification error can be reduced. To evaluate the proposed algorithm (CALO-SVM), the experiment adopted six standard datasets which are obtained from UCI machine learning data repository. For verification, the results of the CALO-SVM algorithm are compared with grid search, which is a conventional method of searching parameter values, standard Ant Lion Optimization (ALO) SVM, and three well-known optimization algorithms: Genetic Algorithm (GA), Particle Swarm Optimization (PSO), and Social Emotional Optimization Algorithm (SEOA). The experimental results proved that the proposed algorithm is capable of finding the optimal values of the SVM parameters and avoids the local optima problem. The results also demonstrated lower classification error rates compared with GA, PSO, and SEOA algorithms.
Alaa Tharwat, Yasmine S. Moemen, and A. E. Hassanien,
"Classification of toxicity effects of biotransformed hepatic drugs using whale optimized support vector machines",
Journal of Biomedical Informatics, vol. 68, pp. 132-149 , 2017.
AbstractMeasuring toxicity is an important step in drug development. Nevertheless, the current experimental methods used to estimate the drug toxicity are expensive and time-consuming, indicating that they are not suitable for large-scale evaluation of drug toxicity in the early stage of drug development. Hence, there is a high demand to develop computational models that can predict the drug toxicity risks. In this study, we used a dataset that consists of 553 drugs that biotransformed in liver. The toxic effects were calculated for the current data, namely, mutagenic, tumorigenic, irritant and reproductive effect. Each drug is represented by 31 chemical descriptors (features). The proposed model consists of three phases. In the first phase, the most discriminative subset of features is selected using rough set-based methods to reduce the classification time while improving the classification performance. In the second phase, different sampling methods such as Random Under-Sampling, Random Over-Sampling and Synthetic Minority Oversampling Technique (SMOTE), BorderLine SMOTE and Safe Level SMOTE are used to solve the problem of imbalanced dataset. In the third phase, the Support Vector Machines (SVM) classifier is used to classify an unknown drug into toxic or non-toxic. SVM parameters such as the penalty parameter and kernel parameter have a great impact on the classification accuracy of the model. In this paper, Whale Optimization Algorithm (WOA) has been proposed to optimize the parameters of SVM, so that the classification error can be reduced. The experimental results proved that the proposed model achieved high sensitivity to all toxic effects. Overall, the high sensitivity of the WOA + SVM model indicates that it could be used for the prediction of drug toxicity in the early stage of drug development.
Hassanien, A. E., and J. M. H. Ali,
"Classification of digital mammography algorithm based on rough set theory",
Automatic Control and Computer Sciences, vol. 37, no. 6: ALLERTON PRESS INC 18 WEST 27TH ST, NEW YORK, NY 10001 USA, pp. 64–71, 2003.
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Hafez, A. I., E. T. Al-Shammari, A. E. Hassanien, and A. A. Fahmy,
"Community detection in social networks using logic-based probabilistic programming",
International Journal of Social Network Mining, vol. 2, no. 2: Inderscience Publishers (IEL), pp. 158–172, 2015.
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