Enzyme Function Classification: Reviews, Approaches, and Trends:

Sharif, M. M., Alaa Tharwat, A. E. Hassanien, and H. A. Hefny, "Enzyme Function Classification: Reviews, Approaches, and Trends: ", Handbook of Research on Machine Learning Innovations and Trends , USA, IGI, USA pp. 26 , 2017.


Enzymes are important in our life and it plays a vital role in the most biological processes in the living organisms and such as metabolic pathways. The classification of enzyme functionality from a sequence, structure data or the extracted features remains a challenging task. Traditional experiments consume more time, efforts, and cost. On the other hand, an automated classification of the enzymes saves efforts, money and time. The aim of this chapter is to cover and reviews the different approaches, which developed and conducted to classify and predict the functions of the enzyme proteins in addition to the new trends and challenges that could be considered now and in the future. The chapter addresses the main three approaches which are used in the classification the function of enzymatic proteins and illustrated the mechanism, pros, cons, and examples for each one.

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