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2022
Soliman, S. M., K. A. R. E. E. M. O. M. A. R. RASHWAN, M. teaima, B. R. Jasti, M. A. El-Nabarawi, and K. M. Abdel-Haleem, "TRANSETHOSOMES AS BREAKTHROUGH TOOL FOR CONTROLLED TRANSDERMAL DELIVERY OF DEXKETOPROFEN TROMETAMOL: DESIGN, FABRICATION, STATISTICAL OPTIMIZATION, IN VITRO, AND EX VIVO CHARACTERIZATION", International Journal of Applied Pharmaceutics, vol. 14, issue 6, pp. 51-57, 2022.
Elsayed, E. M., K. Wassif, and H. Bayomi, "Transfer Learning and Recurrent Neural Networks for Automatic Arabic Sign Language Recognition", The 8th International Conference on Advanced Machine Learning and Technologies and Applications (AMLTA2022): Lecture Notes on Data Engineering and Communications Technologies, vol 113. Springer, Cham., 2022.
Wahed, M. A., N. Saleh, and A. M. Salaheldin, "Transfer learning‐based platform for detecting multi‐classification retinal disorders using optical coherence tomography images", International Journal of Imaging Systems and Technology, vol. 32, issue 3, pp. 740-752, 2022.
Fadeel, D. A. A., M. Fadel, A. Tawfik, and Y. Omar, "Transfersomal eosin topical delivery assisted by fractional CO2 laser for photodynamic treatment of palmar hyperhidrosis: case study", Drug Delivery and Translational Research, 2022. AbstractWebsite
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Fadeel, D.A., fadel, Tawfik, A., and Y. Omar, "Transfersomal eosin topical delivery assisted by fractional CO2 laser for photodynamic treatment of palmar hyperhidrosis: case study", Drug Delivery and Translational Research, , vol. 12, issue 12, pp. 3000-3006, 2022.
Mofed, D., S. Sabet, A. A. Baiomy, and T. Z. Salem, "The Transgene Expression of the Immature Form of the HCV Core Protein (C191) and the LncRNA MEG3 Increases Apoptosis in HepG2 Cells.", Current issues in molecular biology, vol. 44, issue 8, pp. 3632-3647, 2022. Abstract

Long non-coding RNAs (lncRNAs) are regulated in cancer cells, including lncRNA MEG3, which is downregulated in Hepatocellular Carcinoma (HCC). In addition, hepatitis C virus (HCV) core proteins are known to dysregulate important cellular pathways that are linked to HCC development. In this study, we were interested in evaluating the overexpression of lncRNA MEG3, either alone or in combination with two forms of HCV core protein (C173 and C191) in HepG2 cells. Cell viability was assessed by MTT assay. Transcripts' levels of key genes known to be regulated in HCC, such as , , miRNA152, , and were measured by qRT-PCR. Protein expression levels of caspase-3 and MKI67 were determined by immunocytochemistry and apoptosis assays. The co-expression of lncRNA MEG3 and C191 resulted in a marked increase and accumulation of dead cells and a reduction in cell viability. In addition, a marked increase in the expression of tumor suppressor genes ( and miRNA152), as well as a marked decrease in the expression of oncogenes (, BCL2, and ), were detected. Moreover, apoptosis assay results revealed a significant increase in total apoptosis (early and late). Finally, immunocytochemistry results detected a significant increase in apoptotic marker caspase-3 and a decrease in tumor marker MKI67. In this study, transgene expression of C191 and lncRNA MEG3 showed induction in apoptosis in HepG2 cells greater than the expression of each one alone. These results suggest potential anticancer characteristics.

Mofed, D., S. Sabet, A. A. Baiomy, and T. Z. Salem, "The Transgene Expression of the Immature Form of the HCV Core Protein (C191) and the LncRNA MEG3 Increases Apoptosis in HepG2 Cells.", Current issues in molecular biology, vol. 44, issue 8, pp. 3632-3647, 2022. Abstract

Long non-coding RNAs (lncRNAs) are regulated in cancer cells, including lncRNA MEG3, which is downregulated in Hepatocellular Carcinoma (HCC). In addition, hepatitis C virus (HCV) core proteins are known to dysregulate important cellular pathways that are linked to HCC development. In this study, we were interested in evaluating the overexpression of lncRNA MEG3, either alone or in combination with two forms of HCV core protein (C173 and C191) in HepG2 cells. Cell viability was assessed by MTT assay. Transcripts' levels of key genes known to be regulated in HCC, such as , , miRNA152, , and were measured by qRT-PCR. Protein expression levels of caspase-3 and MKI67 were determined by immunocytochemistry and apoptosis assays. The co-expression of lncRNA MEG3 and C191 resulted in a marked increase and accumulation of dead cells and a reduction in cell viability. In addition, a marked increase in the expression of tumor suppressor genes ( and miRNA152), as well as a marked decrease in the expression of oncogenes (, BCL2, and ), were detected. Moreover, apoptosis assay results revealed a significant increase in total apoptosis (early and late). Finally, immunocytochemistry results detected a significant increase in apoptotic marker caspase-3 and a decrease in tumor marker MKI67. In this study, transgene expression of C191 and lncRNA MEG3 showed induction in apoptosis in HepG2 cells greater than the expression of each one alone. These results suggest potential anticancer characteristics.

Mohamed, A. M., and N. K. Allam, "Transition Metal Selenide (TMSe) electrodes for electrochemical capacitor devices: A critical review", Journal of Energy Storage, vol. 47, pp. 103565, 2022.
Abu-Seida, A. M., "Treatment of a congenital lateral patellar luxation by recession trochleoplasty in a donkey foal", Equine Veterinary Education, vol. 34, issue 1, pp. e35-e39, 2022. patellar_luxation_in_a_donkey.pdf
Abu-Seida, A. M., and A. A. Shamaa, "Treatment of a congenital lateral patellar luxation by recession trochleoplasty in a donkey foal. (2022)", Equine Veterinary Education, issue 34 (1), pp. 35-39, 2022.
O.A., H., M. R.R., K. M.T.H.A., M. E.A., and N. N.A., "Treatment of industrial wastewater containing copper and lead ions using new carboxymethyl chitosan-activated carbon derivatives", Egyptian Journal of Chemistry, vol. 65(2), pp. pp. 123–132, 2022. ejchem_volume_65_issue_2_pages_123-132.pdf
Nisar, S., A. M. Alshanberi, A. H. Mousa, M. El Said, F. Hassan, A. Rehman, and S. A. Ansari, "Trend of social media use by undergraduate medical students; a comparison between medical students and educators", Annals of Medicine and Surgery, vol. 81: LWW, 2022. Abstract
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Elnabawy, A. O., E. A. Murray, and M. Mavrikakis, "Trends in Formic Acid Electro-Oxidation on Transition Metals Alloyed with Platinum and Palladium", The Journal of Physical Chemistry C, vol. 126, issue 9: American Chemical Society, pp. 4374-4390, 2022. Abstract
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Shamma, R. N., R. H. Sayed, H. Madry, N. S. El Sayed, and M. Cucchiarini, "Triblock Copolymer Bioinks in Hydrogel Three-Dimensional Printing for Regenerative Medicine: A Focus on Pluronic F127.", Tissue engineering. Part B, Reviews, vol. 28, issue 2, pp. 451-463, 2022. Abstract

Three-dimensional (3D) bioprinting is a novel technique applied to manufacture semisolid or solid objects via deposition of successive thin layers. The widespread implementation of the 3D bioprinting technology encouraged scientists to evaluate its feasibility for applications in human regenerative medicine. 3D bioprinting gained much interest as a new strategy to prepare implantable 3D tissues or organs, tissue and organ evaluation models to test drugs, and cell/material interaction systems. The present work summarizes recent and relevant progress based on the use of hydrogels for the technology of 3D bioprinting and their emerging biomedical applications. An overview of different 3D printing techniques in addition to the nature and properties of bioinks used will be described with a focus on hydrogels as suitable bioinks for 3D printing. A comprehensive overview of triblock copolymers with emphasis on Pluronic F127 (PF127) as a bioink in 3D printing for regenerative medicine will be provided. Several biomedical applications of PF127 in tissue engineering, particularly in bone and cartilage regeneration and in vascular reconstruction, will be also discussed. Impact statement The current review highlights the use of three-dimensional (3D) bioprinting for regenerative medicine, stressing the manipulation of hydrogels as the most commonly used bioinks. The advantages and shortcomings of using hydrogels for 3D printing procedures are discussed with a particular focus on triblock copolymers and Pluronics. A brief overview of applying bioink Pluronic F127 in applications of 3D bioprinting for tissue reconstruction is also provided.

Shamma, R. N., R. H. Sayed, H. Madry, N. S. El Sayed, and M. Cucchiarini, "Triblock Copolymer Bioinks in Hydrogel Three-Dimensional Printing for Regenerative Medicine: A Focus on Pluronic F127.", Tissue engineering. Part B, Reviews, vol. 28, issue 2, pp. 451-463, 2022. Abstract

Three-dimensional (3D) bioprinting is a novel technique applied to manufacture semisolid or solid objects via deposition of successive thin layers. The widespread implementation of the 3D bioprinting technology encouraged scientists to evaluate its feasibility for applications in human regenerative medicine. 3D bioprinting gained much interest as a new strategy to prepare implantable 3D tissues or organs, tissue and organ evaluation models to test drugs, and cell/material interaction systems. The present work summarizes recent and relevant progress based on the use of hydrogels for the technology of 3D bioprinting and their emerging biomedical applications. An overview of different 3D printing techniques in addition to the nature and properties of bioinks used will be described with a focus on hydrogels as suitable bioinks for 3D printing. A comprehensive overview of triblock copolymers with emphasis on Pluronic F127 (PF127) as a bioink in 3D printing for regenerative medicine will be provided. Several biomedical applications of PF127 in tissue engineering, particularly in bone and cartilage regeneration and in vascular reconstruction, will be also discussed. Impact statement The current review highlights the use of three-dimensional (3D) bioprinting for regenerative medicine, stressing the manipulation of hydrogels as the most commonly used bioinks. The advantages and shortcomings of using hydrogels for 3D printing procedures are discussed with a particular focus on triblock copolymers and Pluronics. A brief overview of applying bioink Pluronic F127 in applications of 3D bioprinting for tissue reconstruction is also provided.

Younessr, R. A., M. S. Ame, and M. A. Taha, "Tribo-mechanical measurements and in vivo performance of zirconia-containing biphasic calcium phosphate material implanted in a rat model for bone replacement applications", Materials Chemistry and Physics, vol. 285, issue (3), pp. 126085, 2022.
Alghuthaymi, M. A., K. A. Abd-Elsalam, H. M. AboDalam, F. K. Ahmed, M. Ravichandran, A. Kalia, and M. Rai, "Trichoderma: An eco-friendly source of nanomaterials for sustainable agroecosystems", Journal of Fungi, vol. 8, issue 4: MDPI, pp. 367, 2022. Abstract
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Eitta, M. R. A., A. Sadek, N. A. amer, N. Samy, and N. Abdallah, "Trichogenic effect of low level laser therapy combined with platelet rich plasma for the management of androgenetic alopecia", International Journal of Health Sciences, vol. 6, issue S2, 2022.
Zaki, S. A., S. A. Ouf, K. A. Abd-Elsalam, A. A. Asran, M. M. Hassan, A. Kalia, and F. M. Albarakaty, "Trichogenic Silver-Based Nanoparticles for Suppression of Fungi Involved in Damping-Off of Cotton Seedlings", Microorganisms, vol. 10, no. 2, 2022. AbstractWebsite

Mycogenic silver nanoparticles (AgNPs) produced by some biocontrol agents have shown the ability to inhibit the growth of numerous plant pathogenic fungi, which may be a unique method of disease management. This study describes the extracellular production of AgNPs by Trichoderma harzianum. The size, shape, charge, and composition of the AgNPs were subsequently studied by UV-visible spectroscopy, DLS, zeta potential, TEM, SEM, and EDX, among other methods. The AgNPs had sizes ranging from 6 to 15 nm. The antifungal activities of bio-synthesized AgNPs and two commercial fungicides (Moncut and Maxim XL) were tested against three soil-borne diseases (Fusarium fujikuroi, Rhizoctonia solani, and Macrophomina phaseolina). Cotton seedling illnesses were significantly reduced under greenhouse settings after significant in vitro antifungal activity was documented for the control of plant pathogenic fungi. The use of biocontrol agents such as T. harzianum, for example, may be a safe strategy for synthesizing AgNPs and using them to combat fungus in Egyptian cotton.

ElBassiouni, S. O., and I. R. Abdel-Shafi, Trichomonas, : Elsevier, 2022. Abstract
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Soliman, M. M., T. Hesselberg, A. A. Mohamed, and D. Renault, "Trophic transfer of heavy metals along a pollution gradient in a terrestrial agro-industrial food web", Geoderma, vol. 413, pp. 115748, 2022. AbstractWebsite

Heavy metal contamination across the food web is a growing concern because of increasing environmental discharges in industrial zones, atmospheric transport, and deposition and erosion during rainfall events. We examined the transfer pathways of chromium (Cr) and nickel (Ni) through a terrestrial trophic web and investigated the potential for their bioaccumulation along the trophic chain. Soil, plants, arthropods, and vertebrates were sampled from different localities in the south of Cairo (El-Tebbin, Egypt) and the amounts of Cr and Ni from these samples were measured. We also computed a body condition index (BCI) for vertebrates to estimate individual health and fitness levels in relation to heavy metal concentrations in the liver. The levels of Cr and Ni varied significantly among the samples. Lower trophic levels showed a tendency for biomagnification, while higher trophic levels showed possible biodilution of the two heavy metals: arthropods, amphibians, and lizards concentrated more Cr and Ni than the other taxonomic groups; conversely birds and small mammals generally showed lower levels of Cr and Ni. A negative relationship was obtained when the concentrations of Cr in the soil, plant, and arthropods, and the concentrations of Ni in the wolf spider were plotted as a function of the distance to the industrial area. A significant inverse relationship was found between the Ni concentration of liver and body length, while body mass had no significant effect. Our study thus highlights the varied effects of heavy metal concentrations across a complex food web at different distances from the pollution source, and the need for further studies of their effect on multiple species in an ecosystem.

Nasr, G. M., A. A. El-Sherif, M. M. Omar, E. Mousa, and Reham Osama, "TSDC studies of LASER irradiated and unirradiated PVDF composites doped with Pd (II) benzimidazole complex", Journal of Multidisciplinary Engineering Science and Technology, 2022.
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