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2022
Zheng Li, Ahmed R Henawy, A. H. Q. F. D. D. R. H. A., "A Wild Rice Rhizobacterium Burkholderia cepacia BRDJ Enhances Nitrogen Use Efficiency in Rice", International Journal of Molecular Sciences, vol. 23, issue 18, pp. 10769, 2022.
Nada, H., and N. Nagui, "Wilson-Jones angiosarcoma of the scalp associated with alopecia and chest edema", Journal of the Egyptian Women's Dermatologic Society,, 2022.
Abdel-Hameed, A. M., M. E. L. - S. Abuarab, N. Al-Ansari, H. S. Mehawed, M. A. Kassem, H. He, Y. Gyasi-Agyei, and A. Mokhtar, "Winter Potato Water Footprint Response to Climate Change in Egypt", Atةosphere, vol. 13, issue 7, pp. 1-16, 2022.
EL-HAMEED, A. B. D., M. E. S. A.M., Abuarab, N. Al-Ansari, H. S. Mehawed, M. A. Kassem, H. He, Y. Gyasi-Agyei, and A. Mokhtar, "Winter Potato Water Footprint Response to Climate Change in Egypt", Atmosphere, vol. 13, issue 7, pp. 1052, 2022. winter_potato_water_footprint_response_to_climate_change.pdf
Mekawy Ouda, A. M., and K. Hassan, "Wooden Kohl Tube with Hieratic Inscriptions at the Egyptian Museum Cairo (CG 44703/JE 18553)", The World of Middle Kingdom Egypt , vol. III, issue 12, 2022.
Tantawy, S. A., B. A. Halwachi, A. A. Ghanim, A. A. Mansoori, and D. M. Kamel, "Work-related musculoskeletal disorders among employees with different tasks: an Ahlia University case study", Physiotherapy Quarterly, vol. 30, issue 4, pp. 59-64, 2022. wrmsds_among_ahlia_employees.pdf
Zaki, R. M., V. D. Seshadri, A. S. Mutayran, L. A. Elsawaf, A. M. Hamad, A. S. Almurshedi, R. M. Yusif, and M. Said, Wound Healing Efficacy of Rosuvastatin Transethosomal Gel, I Optimal Optimization, Histological and In Vivo Evaluation, , 2022.
Thabet, R. H., M. K. Fouad, S. A. E. Sherbiny, and M. A. Tony, "Zero-waste approach: assessment of aluminum-based waste as a photocatalyst for industrial wastewater treatment ecology", International Journal of Environmental Research, vol. 16, issue 3: Springer International Publishing Cham, pp. 36, 2022. Abstract
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Abdelaziz, I., M. Kotb, N. Yassin, W. A. Rabie, A. Alsayed, and D. Hamed, "Zinc Supplementation Improves Nocturnal Asthma Symptoms", Pediatric Sciences Journal, vol. 2, issue 1, pp. 10-16, 2022. cupsj_volume_2_issue_1_pages_10-16.pdf
Abdelaziz, I., M. Kotb, N. Yassin, A. Alsayed, W. Rabie, and D. Hamed, "Zinc Supplementation Improves Nocturnal Asthma Symptoms", Pediatric Sciences Journal, vol. 2, no. 1: Cairo University, Faculty of Medicine, Department of Pediatrics, pp. 10–16, 2022. Abstract
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Duncan, W. J., Sunyoung Ma, A. Siddiqi, and R. B. Osman, "Zirconia versus Titanium Implants: 8-Year Follow-Up in a Patient Cohort Contrasted with Histological Evidence from a Preclinical Animal Model.", Materials (Basel, Switzerland), vol. 15, issue 15, 2022. Abstract

UNLABELLED: Zirconia ceramic (ZC) implants are becoming more common, but comparisons between preclinical histology and long-term clinical trials are rare. This investigation comprised (1) 8-year clinical follow-up of one-piece ZC or titanium (Ti) implants supporting full overdentures and (2) histomorphometric analysis of the same implants in an animal model, comparing implants with various surface treatments.

METHODS: (1) Clinical trial: 24 completely edentulous participants (2 groups of N = 12) received 7 implants (one-piece ball-abutment ZC or Ti; maxilla N = 4, mandible N = 3) restored with implant overdentures. Outcomes after 8-years included survival, peri-implant bone levels, soft-tissue responses, and prosthodontic issues. (2) Preclinical trial: 10 New Zealand sheep received 4 implants bilaterally in the femoral condyle: Southern Implants ZC or Ti one-piece implants, identical to the clinical trial, and controls: Southern ITC two-piece implants with the same surface or Nobel (NBC) anodised (TiUnite™) surface. %Bone-implant contact (%BIC) was measured after 12 weeks of unloaded healing.

RESULTS: 8 of 24 participants (33%) of an average age of 75 ± 8 years were recalled; 21% of original participants had died, and 46% could not be contacted. 80.4% of implants survived; excluding palatal sites, 87.5% of Ti and 79% of ZC implants survived. All failed implants were in the maxilla. Three ZC implants had fractured. Bone loss was similar for Ti vs. ZC; pocket depths ( = 0.04) and attachment levels ( = 0.02) were greater for Ti than ZC implants. (1.7 ± 1.6 mm vs. 1.6 ± 1.3 mm). All implants in sheep femurs survived. %BIC was not statistically different for one-piece blasted surface Ti (80 ± 19%) versus ZC (76 ± 20%) or ITC (75 ± 16 mm); NBC had significantly higher %BIC than ITC (84 ± 17%, = 0.4).

CONCLUSION: Short-term preclinical results for ZC and Ti one-piece implants showed excellent bone-implant contact in unloaded femoral sites. This differed from the long-term clinical results in older-aged, edentulous participants. While ZC and Ti implants showed equivalent performance, the risks of peri-implantitis and implant loss in older, completely edentulous patients remain a significant factor.

Mamdouh, S., Mohamed, Mohamed, and W. S. Fahmy, "Zn contamination stimulate agonistic behavior and oxidative stress of crayfishes (Procambarus clarkii).", Journal of Trace Elements in Medicine and Biology, vol. 2022, pp. 126895, 2022.
Soliman, M. M., R. M. El-Hady, and M. S. A. El-Hawagry, "Zoogeography and diversity patterns of the family Cicadellidae (Hemiptera) in Toshka Region, Egypt", Journal of Natural History, vol. 56, issue 25-28, pp. 1199-1213, 2022. zoogeography_and_diversity_patterns_of_the_family_cicadellidae_hemiptera_in_toshka_region_egypt.pdf
Soliman, M. M., R. M. El-Hady, and M. S. A. El-Hawagry, "Zoogeography and diversity patterns of the family Cicadellidae (Hemiptera) in Toshka Region, Egypt", Journal of Natural History, vol. 56, no. 25-28: Taylor & Francis, pp. 1199-1213, 2022. AbstractWebsite

ABSTRACTLeafhoppers (family: Cicadellidae) are among the most common plant sap-sucking pests, causing damage to wild and agronomic plants worldwide. The current paper aims to assess the zoogeography, diversity and population dynamics of the leafhopper species in an agricultural land converted ecosystem. Twenty species (two identified only to the genus level) belonging to 17 genera, 10 tribes, and three subfamilies were collected from Toshka Region, Aswan Governorate, Egypt, in 2020. The most common cicadellid species was Orosius albicinctus, representing 46.7% of the total catch. Low values of species richness and diversity were measured for leafhopper species as compared with those reported in our recent study carried out in Alexandria and Qena governorates. In sum, conversion of any natural ecosystem to agricultural land uses may cause declines in insect diversity. However, desert conversion may increase the diversity pattern of some insect pests. Analysis of the zoogeographic affinities of the leafhopper species from Toshka Region indicated a closer affiliation to the Palaearctic Region (35%) than any other region. Most leafhopper populations exhibited a unimodal seasonal pattern and were abundant in hot and dry months (May–September). The abundance of some leafhopper species correlated positively with temperature (seven species) and negatively with relative humidity (nine species). Six of these species correlated with both variables. This study is the first to investigate leafhopper communities in a converted ecosystem of Toshka Depression, Western Desert.

WalyEldeen, A. A., H. A. I. D. A. N. M. EL-SHORBAGY, H. M. Hassaneen, I. A. Abdelhamid, S. Sabet, and S. A. A. Ibrahim, "[1, 2, 4] Triazolo [3, 4-a] isoquinoline chalcone derivative exhibits anticancer activity via induction of oxidative stress, DNA damage, and apoptosis in Ehrlich solid carcinoma-bearing mice", Naunyn-Schmiedeberg's Archives of Pharmacology, vol. 395, issue 10: Springer Berlin Heidelberg, pp. 1225-1238, 2022. Abstract
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WalyEldeen, A. A., H. A. I. D. A. N. M. EL-SHORBAGY, H. M. Hassaneen, I. A. Abdelhamid, S. Sabet, and S. A. A. Ibrahim, "[1, 2, 4] Triazolo [3, 4-a] isoquinoline chalcone derivative exhibits anticancer activity via induction of oxidative stress, DNA damage, and apoptosis in Ehrlich solid carcinoma-bearing mice", Naunyn-Schmiedeberg's Archives of Pharmacology, vol. 395, issue 10: Springer Berlin Heidelberg, pp. 1225-1238, 2022. Abstract
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WalyEldeen, A. A., H. A. I. D. A. N. M. EL-SHORBAGY, H. M. Hassaneen, I. A. Abdelhamid, S. Sabet, and S. A. A. Ibrahim, "[1,2,4] Triazolo [3,4-a]isoquinoline chalcone derivative exhibits anticancer activity via induction of oxidative stress, DNA damage, and apoptosis in Ehrlich solid carcinoma-bearing mice.", Naunyn-Schmiedeberg's archives of pharmacology, vol. 395, issue 10, pp. 1225-1238, 2022. Abstracts00210-022-02269-5.pdf

Despite the advances made in cancer therapeutics, their adverse effects remain a major concern, putting safer therapeutic options in high demand. Since chalcones, a group of flavonoids and isoflavonoids, act as promising anticancer agents, we aimed to evaluate the in vivo anticancer activity of a synthetic isoquinoline chalcone (CHE) in a mice model with Ehrlich solid carcinoma. Our in vivo pilot experiments revealed that the maximum tolerated body weight-adjusted CHE dose was 428 mg/kg. Female BALB/c mice were inoculated with Ehrlich ascites carcinoma cells and randomly assigned to three different CHE doses administered intraperitoneally (IP; 107, 214, and 321 mg/kg) twice a week for two consecutive weeks. A group injected with doxorubicin (DOX; 4 mg/kg IP) was used as a positive control. We found that in CHE-treated groups: (1) tumor weight was significantly decreased; (2) the total antioxidant concentration was substantially depleted in tumor tissues, resulting in elevated oxidative stress and DNA damage evidenced through DNA fragmentation and comet assays; (3) pro-apoptotic genes p53 and Bax, assessed via qPCR, were significantly upregulated. Interestingly, CHE treatment reduced immunohistochemical staining of the proliferative marker ki67, whereas BAX was increased. Notably, histopathological examination indicated that unlike DOX, CHE treatment had minimal toxicity on the liver and kidney. In conclusion, CHE exerts antitumor activity via induction of oxidative stress and DNA damage that lead to apoptosis, making CHE a promising candidate for solid tumor therapy.

WalyEldeen, A. A., H. A. I. D. A. N. M. EL-SHORBAGY, H. M. Hassaneen, I. A. Abdelhamid, S. Sabet, and S. A. A. Ibrahim, "[1,2,4] Triazolo [3,4-a]isoquinoline chalcone derivative exhibits anticancer activity via induction of oxidative stress, DNA damage, and apoptosis in Ehrlich solid carcinoma-bearing mice.", Naunyn-Schmiedeberg's archives of pharmacology, vol. 395, issue 10, pp. 1225-1238, 2022. Abstract

Despite the advances made in cancer therapeutics, their adverse effects remain a major concern, putting safer therapeutic options in high demand. Since chalcones, a group of flavonoids and isoflavonoids, act as promising anticancer agents, we aimed to evaluate the in vivo anticancer activity of a synthetic isoquinoline chalcone (CHE) in a mice model with Ehrlich solid carcinoma. Our in vivo pilot experiments revealed that the maximum tolerated body weight-adjusted CHE dose was 428 mg/kg. Female BALB/c mice were inoculated with Ehrlich ascites carcinoma cells and randomly assigned to three different CHE doses administered intraperitoneally (IP; 107, 214, and 321 mg/kg) twice a week for two consecutive weeks. A group injected with doxorubicin (DOX; 4 mg/kg IP) was used as a positive control. We found that in CHE-treated groups: (1) tumor weight was significantly decreased; (2) the total antioxidant concentration was substantially depleted in tumor tissues, resulting in elevated oxidative stress and DNA damage evidenced through DNA fragmentation and comet assays; (3) pro-apoptotic genes p53 and Bax, assessed via qPCR, were significantly upregulated. Interestingly, CHE treatment reduced immunohistochemical staining of the proliferative marker ki67, whereas BAX was increased. Notably, histopathological examination indicated that unlike DOX, CHE treatment had minimal toxicity on the liver and kidney. In conclusion, CHE exerts antitumor activity via induction of oxidative stress and DNA damage that lead to apoptosis, making CHE a promising candidate for solid tumor therapy.