@inbook {235456,
	title = {Dietary polyphenols as therapeutic agents to combat COVID-19},
	booktitle = {Coronavirus Drug Discovery: Druggable Targets and In Silico Update: Volume 3},
	year = {2022},
	note = {<p>Export Date: 24 May 2024; Cited By: 1</p>
},
	month = {2022},
	pages = {203 - 215},
	abstract = {<p>The emerging outbreak of COVID-19 infection posed serious threat to human lives, claiming thousands of deaths worldwide. Both the emergence and subsequent transmission of SARS-CoV-2 underscore the urgent and critical need for the identification and development of effective preventive and therapeutic agents against COVID-19. This chapter aims to focus on promising anti-COVID-19 dietary polyphenols such as hesperidin, naringenin, Epigallocatechin gallate, and curcumin, their mechanism of action, safe dosage, toxicity, and bioavailability for future public health practices and research. Based on various computational, in~vitro and in~vivo pieces of evidence supporting efficacy, safety, and good bioavailability of polyphenols, this chapter demonstrates the potential of these entities for the prevention and development of therapeutics for the management of COVID-19. Although dietary polyphenols have been systematically studied from pharmacological point of view, a vast field of pr-clinical and clinical exploration still appears to be open for the research to fully validate their potential for the treatment of viral infections. {\textcopyright} 2022 Elsevier Inc. All rights reserved.</p>
},
	url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85142850216\&doi=10.1016\%2fB978-0-323-95578-2.00016-9\&partnerID=40\&md5=bb21069bf2e2ae109332e3e131a7fb7f},
	author = {Sarfraz, I. and Rasul, A. and Adem, {\c S}. and Ucak, I. and Sarfraz, A. and Bukhari, S.A. and Elfiky, A.A.}
}
