Publications

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2014
SM, A., G. A, K. WT, G. AA, A. - F. DS, R. LA, A. HM, and A. - A. MT., "Bridging defects in chronic spinal cord injury using peripheral nerve grafts combined with a chitosan-laminin scaffold and enhancing regeneration through them by co-transplantation with bone-marrow-derived mesenchymal stem cells: case series of 14 patient", J Spinal Cord Med., vol. 37, issue 1, pp. 54-71, 2014.
Abdelhamid, M., Y Sharaf, S. Bakhoum, D. Sabry, and A. Talaat, "Circulating EPCs predicts the occurrence of major adverse cardiac events and early adverse remodeling in patients with STEMI", EUROPEAN HEART JOURNAL, OXFORD UNIV PRESS, 35, pp. 651-651, 2014.
Sabry, D., A. Osama, N Idriss, and M. Magdy, "Comparative study between the effects of human CD34+ and rat bone marrow mesenchymal stem cells on amelioration of CCL4 induced liver fibrosis", FEBS JOURNAL, France WILEY-BLACKWELL, 281, pp. 222-222, 2014.
Mazen I Naga, M. A. Amin, Dina A Algendy, ahmed i elbadry, Mai M Fawzi, Ayman R Foda, Serag M Esmat, D. Sabry, L. A. Rashed, and M. Kamal, "Effect of Hemochromatosis gene mutation on HCV response to treatment in the Egyptian population", HEPATOLOGY, WILEY-BLACKWELL, 60, pp. 931A-932A, 2014.
Aziz, M. T. A., M. F. El-Asmar, A. M. Rezq, M. A. A. Wassef, H. Fouad, N. K. Roshy, H. H. Ahmed, L. A. Rashed, D. Sabry, F. M. Taha, et al., "Effects of a novel curcumin derivative on insulin synthesis and secretion in streptozotocin-treated rat pancreatic islets in vitro", Chinese medicine, vol. 9, issue 1, pp. 1-12, 2014.
Lobna A Aly, H. E. - Menoufy, Hesham S Sadeq, A. Ragae, and D. Sabry, "Efficiency of systemic versus intralesional bone marrow-derived stem cells in regeneration of oral mucosa after induction of formocresol induced ulcers in dogs", Dental research journal, vol. 11, issue 2, pp. 212, 2014.
Abdel Aziz, M. T., D. Sabry, M. A. S. Al-Ghussein, A. M. A. Soliman, and A. A. Hassan, "IN VITRO AND IN VIVO EVALUATION ACTIVITIES OF EACH MESENCHYMAL STEM CELLS, DOXORUBICIN AND LPS OR COMBINED ON BREAST CARCINOMA", WORLD JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES, vol. 3, issue 8, pp. 157-176, 2014.
Omar, R. F., R. Ahmed, D. Sabry, Mahmoud Abdel Alim, Mira Atef, and N. Zayed, "Influence of Delta Virus Infection on the Clinical Spectrum, Serologic and Virologic Status in Chronic Hepatitis B Virus Genotype D", HEPATOLOGY, WILEY-BLACKWELL, 60, pp. 971A-972A, 2014.
Salama, M. K., D. Sabry, MA Al-Ghussein, R. Ahmed, S. A. Allah, F. M. Taha, W. Fathy, M. S. Wadie, M. Nabih, A. Abul-Fotouh, et al., "Molecular detection of monocyte chemotactic protein-1 polymorphism in spontaneous bacterial peritonitis patients", World journal of gastroenterology: WJG, vol. 20, issue 33, pp. 11793-11799, 2014.
Shehab, H., D. Sabry, M Mokhtar, M. Mabrouk, W. Elakel, M. Tawfik, Y Korriem, and G. Esmat, "P1101 THE VITAMIN D RECEPTOR FOKI GENE POLYMORPHISM IS ASSOCIATED WITH POOR RESPONSE TO TREATMENT IN CHRONIC HEPATITIS C GENOTYPE 4", HEPATOLOGY, WILEY-BLACKWELL, 60, pp. S445, 2014.
Sabry, D., O. Nouh, S. Marzouk, and A. Hassouna, "Pilot study on molecular quantitation and sequencing of endometrial cytokines gene expression and their effect on the outcome of in vitro fertilization (IVF) cycle", Journal of Advanced Research, vol. 5, issue 5, pp. 595-600, 2014.
Ahmed G Abdel Salam, Hazem M Ata, T. M. Salman, L. A. Rashed, D. Sabry, and M. F. Schaalan, "Potential therapeutic utility of mesenchymal stem cells in inflammatory bowel disease in mice", International immunopharmacology, vol. 22, issue 2, pp. 515-521, 2014.
Mazen I Naga, M. A. Amin, Dina A Algendy, ahmed i elbadry, Mai M Fawzi, Ayman R Foda, Serag M Esmat, D. Sabry, L. A. Rashed, M. Kamal, et al., "The Role Of Genetic Polymorphism Of LDL Receptor In Egyptian Population Infected With Chronic HCV, Regarding Response To Treatment", HEPATOLOGY, WILEY-BLACKWELL, 60, pp. 922A-922A, 2014.
Abdelhamid, M., D. Sabry, D Gharib, and M. Abdel Gawad, "Statin treatment increases the circulating endothelial progenitor cells and improve endothelial function in patients with coronary artery diseases", EUROPEAN HEART JOURNAL, OXFORD UNIV PRESS, 35, pp. 1154-1154, 2014.
Nadia Abdelaaty Abdelkader, Soha Saoud Abdelmoniem, D. Sabry, Amin Mohamad Abdelbaky, Maram M Mahdy, E. Zaky, and W. Elsayed, "Vitamin D and IL28B genotyping as predictors for antiviral therapy: a retrospective study in Egyptian HCV genotype 4a", Tropical Journal of Pharmaceutical Research, vol. 13, issue 10, pp. 1725-1732, 2014.
2013
A, F., S. D, A. R, K. M, Allah SA, Marzouk S, A. M, Abd El Aziz R, El Badri A, K. H, et al., "Comparative diagnostic study of biomarkers using FibroMax™ and pathology for prediction of liver steatosis in patients with chronic hepatitis C virus infection: an Egyptian study.", Int J Gen Med, vol. 12, issue 6, pp. 127-34, 2013.
H, F., Raziky MS, Aziz RA, S. D, Aziz GM, Ewais M, and S. AR., "Dendritic cell co-stimulatory and co-inhibitory markers in chronic HCV: an Egyptian study.", World journal of gastroenterology: WJG, vol. 19, issue 43, pp. 7711-8, 2013.
MT1, A. A., K. HM, E. H. A, R. NK, H. A. A. T. A. W. I. F. Rashed LA, Sabry D, Hassouna AA, T. F, and A. WI., "Effect of mesenchymal stem cells and a novel curcumin derivative on Notch1 signaling in hepatoma cell line.", Biomed Res Int, 2013. Abstract

This study was conducted to evaluate the effect of mesenchymal stem cells (MSCs) and a novel curcumin derivative (NCD) on HepG2 cells (hepatoma cell line) and to investigate their effect on Notch1 signaling pathway target genes. HepG2 cells were divided into HepG2 control group, HepG2 cells treated with MSC conditioned medium (MSCs CM), HepG2 cells treated with a NCD, HepG2 cells treated with MSCs CM and NCD, and HepG2 cells treated with MSCs CM (CM of MSCs pretreated with a NCD). Expression of Notch1, Hes1, VEGF, and cyclin D1 was assessed by real-time, reverse transcription-polymerase chain reaction (RT-PCR) in HepG2 cells. In addition, HepG2 proliferation assay was performed in all groups. Notch1 and its target genes (Hes1 and cyclin D1) were downregulated in all treated groups with more suppressive effect in the groups treated with both MSCs and NCD. Also, treated HepG2 cells showed significant decrease in cell proliferation rate. These data suggest that modulation of Notch1 signaling pathway by MSCs and/or NCD can be considered as a therapeutic target in HCC.

Sabrya, D., O. Nouhb, S. Marzouka, and A. Hassounaa, Pilot study on molecular quantitation and sequencing of endometrial cytokines gene expression and their effect on the outcome of in vitro fertilization (IVF) cycle, , 2013. jare_251_1.pdf
MA1, A., S. D, R. LA, A. WM, el-Ghobary MA, F. MS, F. HA, and Y. YA., "Short-term evaluation of autologous transplantation of bone marrow-derived mesenchymal stem cells in patients with cirrhosis: Egyptian study", Clin Transplant., vol. 27, issue 4, pp. 607-12, 2013. Abstract

Stem cell-based therapy has received attention as a possible alternative to organ transplantation. The aim of this study was to assess the safety and efficacy of autologous transplantation of bone marrow (BM)-derived stromal cells in post-HCV liver cirrhosis patients.
METHODOLOGY:
10 × 10(6) of isolated human bone marrow (HBM)-stromal cells in 10 mL normal saline were injected in the spleen of 20 patients with end-stage liver cirrhosis guided by the ultrasonography, and then patients were followed up on monthly basis for six months.
RESULTS:
A statistically significant decrease was detected in the total bilirubin, aspartate transaminase (AST), alanine transaminase (ALT) (p-value<0.01), prothrombin time (PT), and international normalized ratio (INR) levels (p-value<0.05), while a statistically significant increase in the albumin and PC (p-value<0.05) after follow-up.
CONCLUSION:
This study suggested the safety, feasibility, and efficacy of the intrasplenic injection of autologous BM stromal cells in improving liver function in Egyptian patients with cirrhosis.
© 2013 John Wiley & Sons A/S.

MT, A., El Ibrashy IN, M. DP, R. AM, W. MA, F. HH, A. HH, Sabry DA, Shawky HM, and H. RE., "Signaling mechanisms of a water soluble curcumin derivative in experimental type 1 diabetes with cardiomyopathy.", Diabetol Metab Syndr., vol. 12, issue 5, pp. 13, 2013.
2011
Roshdy, N. K., L. A. Rashed, D. Sabry, A. A. Hassouna, and F. M. Taha, Efficacy of mesenchymal stem cells in suppression of hepatocarcinorigenesis in rats: possible role of Wnt signaling, , 2011. Abstract
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Mokbel, A. N., O. S. El Tookhy, A. A. Shamaa, L. A. Rashed, D. Sabry, and A. M. Elsayed, "Homing and reparative effect of intra-articular injection of autologus mesenchymal stem cells in osteoarthritic animal model", BMC musculoskeletal disorders, vol. 12, no. 1: BioMed Central Ltd, pp. 259, 2011. Abstract
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2010
Haleem, A. M., A. A. El Singergy, D. Sabry, H. M. Atta, L. A. Rashed, C. R. Chu, M. T. El Shewy, A. Azzam, and M. A. T. Aziz, "The Clinical Use of Human Culture–Expanded Autologous Bone Marrow Mesenchymal Stem Cells Transplanted on Platelet-Rich Fibrin Glue in the Treatment of Articular Cartilage Defects A Pilot Study and Preliminary Results", Cartilage, vol. 1, no. 4: SAGE Publications, pp. 253–261, 2010. Abstract
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Abdel Aziz, M. T., S. El-Haggar, T. Mostafa, H. Atta, H. Fouad, S. Mahfouz, L. Rashed, D. Sabry, A. Senbel, and G. A. Ali, "Effect of mesenchymal stem cell penile transplantation on erectile signaling of aged rats", Andrologia, vol. 42, no. 3: Wiley Online Library, pp. 187–192, 2010. Abstract
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