Yu, D. Y., Q. L. Zhao, Z. L. Wei, M. Shehata, and T. Kondo,
"Enhancement of hyperthermia-induced apoptosis by sanazole in human lymphoma U937 cells",
Int J Hyperthermia, vol. 25, no. 5, pp. 364-73, Aug, 2009.
AbstractSanazole has been tested clinically as a hypoxic cell radiosensitizer. The aim of the present study was to investigate whether sanazole enhances apoptosis induced by hyperthermia at 44 degrees C for 20 min in human lymphoma U937 cells. Sanazole alone induced continuous increase in the intracellular superoxide generation in a time-dependent manner and transient increase in the peroxide formation, which further were enhanced at 1 hour after HT treatment. Moreover, when the cells were treated first with 10 mM sanazole for 40 min, exposed to HT at 44 degrees C for 20 min and the cells were further treated with the drug at 37 degrees C for 6 h, a significant enhancement of HT-induced apoptosis was evidenced by DNA fragmentation, morphological changes and phosphatidylserine externalization. Studying the apoptotic pathways involved in this enhancement, we found that loss of the mitochondrial membrane potential, release of cytochrome c from mitochondria to cytosol, and activation of caspase-3 and caspase-8 was enhanced significantly in the U937 cells after the combined treatment. Moreover, this combination enhanced activation of Bid, and down regulation of Hsp70. In addition, an increase in the intracellular Ca(2+) concentration ([Ca(2+)](i)), and externalization of Fas were observed immediately after sanazole and HT treatment. Our data indicate that sanazole can enhance the hyperthermia induced-apoptosis through the Fas-caspase-8- and [Ca(2+)](i)-dependent apoptotic pathways. In addition, the down regulation of Hsp70 contributed to this enhancement.
Al-Sallab, A. A., H. A. H. Fahmy, and M. Rashwan,
"HARDWARE IMPLEMENTATION OF DISTRIBUTED SPEECH RECOGNITION SYSTEM FRONT END",
{EUSIPCO}, 17th {E}uropean {S}ignal {P}rocessing {C}onference, {G}lasgow, {S}cotland, pp. 953–957, aug, 2009.
AbstractModern speech recognition applications are heading towards embedded systems and hand-held devices. Distributed Speech Recognition (DSR) system architecture emerged to address this kind of applications. Most of the existing implementations of this system are presented in software fashion, with little consideration to the end product platform in which the system will be deployed. In this paper, an optimized hardware implementation of the front end part of the DSR specified in the basic ETSI Aurora standard ETSI ES 201 108 is presented in FPGA platform prototype, with consideration of migration to structured ASIC in case of mass-production. Main design issues and tips are highlighted. Results are presented in terms of hardware resources utilization, comparison of some basic system components to third party reference designs and compliance to the Aurora standard.
Said, M., A. Yosry, G. Esmat, M. El-Serafy, A. Omar, W. Doss, A. Hosny, Y. Hatata, E. Marawan, R. R. Kamel, et al.,
"OUTCOME OF LIVING DONOR LIVER TRANSPLANTATION FOR INCIDENTALLY FOUND HEPATOCELLULAR CARCINOMA",
TRANSPLANT INTERNATIONAL, vol. 22, pp. 198, AUG, 2009.
Abstractn/a
Sobh, I., N. Darwish, and M. Fayek,
"Evaluation Approaches for an Arabic Extractive Generic Text Summarization System",
MEDAR, Second International Conference on Arabic Language Resources an Tools, Cairo, Egypt , April, 2009.
Epps, R. W., D. Elmahdy, and T. H. Ismail,
"Sarbanes-Oxley 404 material weaknesses and earning restatements: does corporate governance matter?, ",
American Accounting Association 2009 Southeast Region Meeting, Mississippi University, USA, April 30 – May 2, 2009.
Kudelka, M., V. Snásel, Z. Horak, and A. E. Hassanien,
"From Web Pages to Web Communities",
Annual International Workshop on DAtabases, TExts, Specifications and Objects, Spindleruv Mlyn, Czech Republic , April 15-17, 2009.
Abstract In this paper we are looking for a relationship between the intent of Web pages, their architecture and the communities who take part in their usage and creation. From our point of view, the Web page is entity carrying information about these communities and this paper describes techniques, which can be used to extract mentioned information as well as tools usable in analysis of these information. Information about communities could be used in several ways thanks to our approach. Finally we present an experiment which illustrates the benefits of our approach.
Mostafa, T., T. Anis, H. Imam, A. R. El-Nashar, and I. A. Osman,
"Seminal reactive oxygen species-antioxidant relationship in fertile males with and without varicocele",
Andrologia, vol. 41, no. 2, pp. 125-9, Apr, 2009.
AbstractThe aim of this study was to assess seminal reactive oxygen species (ROS)-antioxidants relationship in fertile and infertile men with and without varicocele. One hundred and seventy six males were studied; fertile healthy volunteers (n = 45), fertile men with varicocele (n = 45), infertile oligoasthenozoospermia (OA, n = 44) without varicocele and infertile OA with varicocele (n = 42). In their seminal plasma, two ROS parameters (malondialdehyde, hydrogen peroxide) and five antioxidants (superoxide dismutase, catalase, glutathione peroxidase, vitaminE, vitaminC) were estimated. Compared with fertile healthy men, in all other studied groups, estimated seminal ROS were significantly higher and estimated antioxidants were significantly lower. Infertile men with varicocele showed the same relationship as infertile men without varicocele. Sperm concentration, total sperm motility as well as sperm normal forms were negatively correlated with seminal malondialdehyde and were positively correlated with vitaminC. It is concluded that varicocele has an oxidative stress (OS) in fertile normozoospermic bearing conditions. This may allow understanding that, within men with varicocele, there is a threshold value of OS over which male fertility may be impaired.
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