Mohamed Zaki

Introduction: Cervical twin ectopic pregnancy after IVF-ET is rare and catastrophic complication. However, here is no consensus on the best treatment strategy. Patient and Method: Case report of cervical twin ectopic pregnancy after IVF-ET treated by transvaginal ultrasoundguided aspiration plus systemic single injection of methotrexate, which followed by full-term delivery in next IVF-ET cycle. Conclusion: Transvaginal ultrasound-guided aspiration and systemic methotrexate administration can be safely and easily used to treat cervical ectopic pregnancies and to preserve the fertility of the patient without any major complications.

Due to advances in medical sciences, many chronic diseases that formerly resulted in early death can now be effectively managed with long-term treatment regimens. Patients with potentially fatal anemias, for example, can be treated with ongoing blood transfusions and iron chelation therapy. Ensuring adherence and persistence is challenging, as the benefits of therapy are not perceived immediately. Poor adherence severely compromises the effectiveness of treatment and, therefore improving compliance in terms of quality of life and health economics is critical. Although adherence to chelation therapy is generally poor, the availability of oral iron chelators may help to improve patient compliance. For chronic conditions such as thalassemia major, even when oral chelation therapy is available, support by an integrated team including a clinical psychologist and nurse specialist working with the treatment center is recommended to achieve optimal results

Purpose: To identify factors that influence binocular function in anisometropic, nonstrabismic children before and after optical correction and amblyopia therapy

GnRH agonists have been the standard treatment for controlled ovarian stimulation in assisted reproduction because of the associated increase in pregnancy rates. However, a drawback of such protocol was the associated increased incidence of ovarian hyperstimulation syndrome.

Schistosomiasis also known as bilharziasis is a parasitic disease that dates back to antiquity. The ancient Egyptians, through settling and cultivating the Nile valley, were among the first to contract the disease. Thus, the main symptom hematuria was mentioned in Egyptian papyri (1500-1800 B.C.), and schistosome eggs were identified in Egyptian mummies through paleopathologic studies. In 1852, Theodor Bilharz, a German pathologist working in Cairo, discovered the worms in the portal circulation and was the first to describe the Pathology of the disease. Ferguson in 1911 was the first to report on the high frequency of bladder cancer in Egypt and to suggest an etiologic relation with urinary Schistosomiasis, a fact which is now generally accepted (Bolkainy & Chu 1981a). The aim of this article is to review the pathobiology of Schistosoma associated bladder cancer (SACB), describe the relationship between Schistiosomiasis and bladder cancer with respect to the mechanisms of carcinogenesis with emphasis on special features of SABC and recent methods of early detection.

Nanobacteria are the smallest described bacteria to date, with dimensions of 0.08 to 0.50 ?m. Furthermore, these organisms were found to produce a biofilm containing hydroxyl apatite or carbonate, preventing their effective staining. They were also isolated from commercial serum used in the cell culture. Nanobacteria have been detected thereafter in blood and blood products derived from horses, as well as blood from human blood donors. Some strains were isolated from kidney stones and bovine sera. To confirm the data, we searched for Nanobacteria from aseptically removed urinary tract stoned. We used scanning electron microscopy for these stones. Our objectives are identification and determination of Nanobacteria by cell co culture and apatite formation by Nanobacteria in Loeffler medium and SF medium. Also production of polyclonal antibodies, immune-fluorescence assays. Moreover, identification using molecular characterization of Nanobacteria by PCR amplification of 16S rRNA gene of selected isolates and cloning for PCR amplified products. Microbiological characteristics:We have reviewed recent publications regarding the microbiological characteristic and pathogenicity of a novel infectious agent, the mineral-forming , sterile-filterable, slow-growing Gram-negative Nanobacteria, detected in bovine/human blood, kidney cyst fluid, urine and kidney stones. According to their 16S rDNA structure, nanobacteria belong to the alpha-2 Proteobacteria, subgroup, which includes the Brucella and Bartonella species. Their cell diameter is 0.2-0.5 microm (the smallest known cell-walled bacteria). Their most remarkable characteristic is the formation of carbonate apatite crystals of neutral pH and at physiologic phosphate and calcium concentrations. The extracellular mineralization forms a hard protective shelter for these hardy microorganisms, and enables them to survive conditions of physical stress that would be lethal to most other bacterial species.

Introduction: Hepatitis C virus (HCV) is frequently associated with rheumatic autoimmune manifestations including rheumatoid-like arthritis.

The structure and magnetic properties of Co1?XCuXFe2O4 were investigated. Cobalt copper ferrites have been synthesized by the double sintering ceramic technique. X-ray diffraction analysis and transmission electron microscopy (TEM) confirmed the formation of single-phase cobalt ferrite nanoparticles. The particle size was estimated by TEM micrography to be 46, 51, 40 and 36 nm for X = 0.0, 0.1, 0.3 and 0.6, respectively, which is a good result for this method of preparation. The magnetic susceptibility was studied at different temperatures as a function of magnetic field intensities. The room temperature hysteresis loop was found for the present samples in a field intensity of 7 kOe using a vibrating sample magnetometer. The parameters of x-ray density (dx) and apparent density (da) increase with increasing Cu2+ concentration in the prepared samples.

Orodispersible film (ODF) technology offers new possibilities for drug delivery by providingthe advantages of oral delivery coupled with the enhanced onset of action and convenience to specialpatient categories such as pediatrics and geriatrics. In this study,mosapride (MOS) was formulated inan ODF preparation that can be used for treatment of patients who suffer