Hussein F. Zohdi
Professor of Organic Chemistry
Department of Chemistry, Faculty of Science, Cairo University, Giza, Egypt 12613 (email)
Reactions and Mechanisms of Aliphatic Compounds (Chem 241)
Course Objectives
This course focuses on ionic and some radical reaction mechanisms appropriate to simple organic compounds as well as the uses of these reactions to carry out simple synthetic transformations.
By the end of this course, the student is expected to:
- Understand the chemistry of alkyl halides, alcohols, carbonyl compounds, aliphatic acids and amines.
- Understand the chemistry of free radicals, and carbocations
- Master a variety of simple reaction mechanisms such as nucleophilic substitution and elimination reactions.
- Understand the stereochemical consequences of substitution (SN1 and SN2) and of elimination reactions (E1and E2).
- Appreciate the influence of the structure of the alkyl group, the nature of the leaving group, the reagent and the solvent on substitution and elimination reactions.
- Understand the mechanisms of nucleophilic addition reactions to carbonyl compounds and appreciate the acidity of the a-hydrogen of carbonyl compounds.
- Describe C-C bond formation by enolate anion reactions, such as Aldol reaction.
Related materials