Karim Soliman

• Formulation and evaluation of patient-convenient effervescent tablets of risperidone.‎

• Improving aqueous solubility of risperidone using different techniques, these ‎included:‎

• Formulation of different drug-polymers solid dispersions using different solvent ‎evaporation techniques (vacuum drying, freeze drying, oven drying).‎ The effects of different concentration of polymers were investigated (pregelatinized starch, cellulose derivatives, inulin, trehalose, Eudragit).
• Formulation of solid self-nanoemulsifying drug delivery systems.‎

• Bioequivalence study of the prepared effervescent tablets on rabbits.‎