El-Khouly, E. A., K. M. Gouda, S. G. Ibrahim, E. M. Ahmed, M. K. El-Sobky, and A. A. M. Ibraheem, "Design, synthesis, and biological evaluation of new triazolopyridazine-based derivatives as cyclin dependent kinase-4 inhibitors with apoptosis-inducing and tumor-suppressive effects", Bioorganic and medicinal chemistry, vol. 132, pp. 118434, Jan 2026.
Hasan, N. K., Z. Mahmoud, M. M. Kandeel, A. A. F. Soliman, and E. A. El-Khouly, "Novel 2,6-Bis(indolyl/ 5-bromoindolyl)dihydropyridine/pyridine hybrids as potential anti-tumor agents: Design, one-pot Green synthesis, molecular docking, and cytotoxicity evaluation", Bioorganic Chemistry, vol. 166, pp. 109058, november 2025.
Kamel, M. M., M. K. Abdel-hameid, H. B. El-Nassan, and E. A. E. - Khouly, "Recent Advances in the Synthesis and Biological Applications of Nortopsentin Analogs", Chemistry of Heterocyclic Compounds, vol. 56, issue 5, pp. 499 - 502, 2020. AbstractWebsite

The present minireview summarizes the data published during the last decade (2012–2019) on the synthesis of nortopsentin analogs and the effect of the structural modifications on the biological activity of the synthesized analogs as antitumor, antifungal, and antiviral agents.

Hasan, N. K., E. A. El-Khouly, Z. Mahmoud, and M. M. Kandeel, " A Deep Insight into the Indole Nucleus: Pharmacological Action, Structure-Activity Relationship, and Eco-Friendly Synthetic Approaches", journal of current organic chemistry, july 2025.
Sobh, E. A., A. S. M. A. A. E. KASSAB, E. A. El-Khouly, and M. S. A. Hassan, "New pyranopyrazole based derivatives: Design, synthesis, and biological evaluation as potential topoisomerase II inhibitors, apoptotic inducers, and antiproliferative agents", Bioorganic Chemistry, vol. 144, 29-1-2024.
Kamel, M. M., M. K. Abdel-hameid, H. B. El-Nassan, and E. A. El-Khouly, "Synthesis and Cytotoxicity Evaluation of Novel Indole Derivatives as Potential Anti-Cancer Agents", medicinal chemistry, vol. 15, issue 8, pp. 873-882, 2019.
Kamel, M. M., M. K. Abdel-hameid, H. B. El-Nassan, and E. A. El-Khouly, "Synthesis and Cytotoxic Activity of Novel Mono- and Bis-Indole Derivatives: Analogues of Marine Alkaloid Nortopsentin", medicinal chemistry, vol. 17, issue 7, pp. 779-789, 2020.
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Korraa, M. M., A. T. Taher, H. B. El-Nassan, and E. A.El-Khouly, "Synthesis of Novel Pyrimidine Derivatives as Potential Anticancer Agents", ’4th International Scientific Conference of Faculty of Pharmacy Cairo university, Cairo Universty, 2013. presentation.pdf
Said, M. M., A. T. Taher, H. B. El-Nassan, and E. A. El-Khouly, "Synthesis of novel S-acyl and S-alkylpyrimidinone derivatives as potential cytotoxic agents", Research on Chemical Intermediates, vol. 42, issue 8, pp. 6643-6662, 2016. our_paper.pdf
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