El-Komy, M. H. M., and N. Samir, "1064 Nd:YAG laser for the treatment of chronic paronychia: a pilot study.", Lasers in medical science, vol. 30, issue 5, pp. 1623-6, 2015 Jul. Abstract

Paronychia, which can be acute or chronic, is characterized by erythema, edema, and tenderness at the proximal and occasionally lateral nail folds. Causes of chronic paronychia include excessive moisture, contact irritants, trauma, and candida infection. Chronic paronychia is usually multifactorial and difficult to treat. The aim of the present work was to assess the role of neodymium-doped yttrium aluminium garnet (Nd:YAG) laser as a new modality for the treatment of chronic paronychia. In this interventional pilot study, eight female patients suffering from long-standing paronychia received 2-5 Nd:YAG laser sessions (4 weeks apart). Fluences ranged between 70 to 80 J/cm(2), using a 2.5-mm spot size handpiece, and pulse duration was set at 0.7 ms. Patients were digitally photographed and clinically evaluated before starting the treatment and at each session. Seven of our patients showed various degree of improvement regarding erythema and swelling of their proximal nail folds. Nail plate abnormalities also improved in six patients. These preliminary results document the efficacy and feasibility of Nd:YAG laser as one of the treatments that could ameliorate chronic paronychia.

El-Komy, M. H. M., and R. Baran, "Acroosteolysis presenting with brachyonychia following exposure to cold.", Journal of the European Academy of Dermatology and Venereology : JEADV, vol. 29, issue 11, pp. 2252-4, 2015 Nov. Abstract

BACKGROUND: A vast number of conditions ranging from simple trauma to hereditary and collagen vascular disease had been described in association with acroosteolysis.

OBJECTIVE: To demonstrate that severe cold exposure not mounting to frostbite may be associated with acroosteolysis.

METHODS: A 16-year-old girl with acroosteolysis presenting with brachyonychia was fully investigated for possible cause of her nail and bone deformity.

RESULTS: Lab investigations including Parathormone levels, Anti Scl 70, ANA, Anti-CCP and RF levels were all normal. X-ray imaging revealed resorption of the tufts of the terminal phalanges bilaterally. Disruption of nail fold capillaries with sluggish flow in capillary loops was evident on capillaroscopy.

CONCLUSION: It had been repeatedly reported that frostbite, Raynaud's disease and diseases associated with repeated chilblains may be associated with secondary cold-induced acroosteolysis. Here, we present a case of acroosteolysis associated with brachyonychia following exposure to severe cold not mounting to frostbite.

ZAHER, H., H. RASHEED, M. M. El-Komy, R. A. HEGAZY, H. I. GAWDAT, D. M. ABDELHALIM, R. M. Abdel Hay, R. A. HEGAZY, and A. M. Mohy, "Propranolol versus captopril in the treatment of infantile hemangioma (IH): A randomized controlled trial.", Journal of the American Academy of Dermatology, vol. 74, issue 3, pp. 499-505, 2016 Mar. Abstract

BACKGROUND: Renin-angiotensin system components have been demonstrated in the biology of infantile hemangioma (IH). Captopril, an angiotensin-converting enzyme inhibitor, is proposed as a therapeutic alternative to oral propranolol.

OBJECTIVES: We sought to compare the benefit of propranolol and captopril in the treatment of IH, and to assess angiotensin-converting enzyme gene polymorphism in patients with IH and in control subjects.

METHODS: Thirty patients with IH and 35 healthy control subjects were enrolled in this study. Patients were randomly assigned to treatment with either propranolol or captopril. Assessment was done clinically and by measurement of serum vascular endothelial growth factor and angiotensin II in patients and control subjects. Angiotensin-converting enzyme gene polymorphism was also studied.

RESULTS: Clinical improvement was significantly better and faster in the patients treated with propranolol. Both groups showed reduced vascular endothelial growth factor and angiotensin II levels posttreatment, with a significantly higher percentage reduction in the propranolol-treated group. Cardiac side effects were reported only in the captopril-treated group. Baseline vascular endothelial growth factor level was significantly higher, and baseline angiotensin II level was significantly lower, in patients than control subjects.

LIMITATIONS: We studied a relatively small number of patients and control subjects.

CONCLUSION: Propranolol shows greater benefit than captopril in the treatment of IH.

EL-KOMY, M. O. H. A. M. E. D. H. U. S. S. E. I. N. M. E. D. H. A. T., M. R. Abdel-Halim, E. A. El-Nabarawy, S. El-Tobshy, S. Shalaby, and A. I. Kamel, "Subungual nodule with recurrent bleeding", Journal of the American Academy of Dermatology, vol. 67, no. 5: Mosby, pp. e229–e230, 2012. Abstract
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El-Moaty, Z. H. A., M. H. El-Komy, R. A. Hegazy, E. K. H. A. Mohamed, and H. H. Ahmed, "Assessment of interleukin-17 and vitamin D serum levels in psoriatic patients.", Journal of the American Academy of Dermatology, vol. 69, no. 5, pp. 840, 2013. Abstract
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Rasheed, H., D. Mahgoub, R. Hegazy, M. El-Komy, A. Hay, M. A. Hamid, and E. Hamdy, "Serum Ferritin and Vitamin D in Female Hair Loss: Do They Play a Role?", Skin pharmacology and physiology, vol. 26, no. 2: Karger Publishers, pp. 101–107, 2013. Abstract
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El-Komy, M. H. M., N. Samir, and O. G. Shaker, "Estimation of vitamin D levels in patients with pemphigus vulgaris", Journal of the European Academy of Dermatology and Venereology: Wiley Online Library, 2013. Abstract
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El-Komy, M., I. Amin, A. Zidan, D. Kadry, O. A. Zeid, and O. Shaker, "Insulin-like growth factor-1 in psoriatic plaques treated with PUVA and methotrexate", Journal of the European Academy of Dermatology and Venereology, vol. 25, no. 11: Wiley Online Library, pp. 1288–1294, 2011. Abstract
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El-Komy, M. H. M., "Nailfold fluconazole fluid injection for fingernail onychomycosis", Clinical and experimental dermatology, vol. 31, no. 3: Wiley Online Library, pp. 465–467, 2006. Abstract
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RAMADAN, S. H. A. H. I. R. A. A. B. D. E. L. - R. A. H. M. A. N., M. O. H. A. M. E. D. H. U. S. S. E. I. N. M. E. D. H. A. T. EL-KOMY, D. A. Bassiouny, and S. E. H. A. M. A. H. M. E. D. EL-TOBSHY, "Subcision versus 100% trichloroacetic acid in the treatment of rolling acne scars", Dermatologic Surgery, vol. 37, no. 5: Wiley Online Library, pp. 626–633, 2011. Abstract
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