Abdel-Ghani, N. T., G. A. El-Chaghaby, and E. M. Zahran, "Pentachlorophenol (PCP) adsorption from aqueous solution by activated carbons prepared from corn wastes", International Journal of environmental and science technology, vol. 12, issue 1, pp. 211-222, 2015.
Abdel-Ghani, N. T., G. A. El-Chaghaby, and E. M. Zahran, "Cost Effective Adsorption of Aluminium and Iron from Synthetic and Real Wastewater by Rice Hull Activated Carbon (RHAC", American Journal of Analytical Chemistry, vol. 6, issue 1, pp. 71-83, 2015.
Mansour, A. M., and N. T. Abdel-Ghani, "Synthesis, spectroscopic, DFT, cytotoxicity and antimicrobial activity of Pd(II) and Pt(II) complexes of N,N-chelated benzimidazole derivatives", Inorganica Chimica Acta, vol. 438, pp. 76-84, 2015.
Abdel-Ghani, N. T., A. M. Mansour, M. A. F. El-Ghar, O. M. El-Borady, and H. Shorafa, "Co(II), Ni(II) and Cu(II) complexes of azo-aminopyrazole ligand: Spectroscopic, crystal structure and quantum chemical calculations", Inorganica Chimica Acta, vol. 435, pp. 187-193, 2015.
Abdel-Ghani, N. T., G. A. El-Chaghaby, and F. S. Helal, "Individual and competitive adsorption of phenol and nickel onto multiwalled carbon nanotubes", Journal of advanced research, vol. 6, issue 3, pp. 405-415, 2015.
Abdel-Ghani, N. T., A. F. Shoukry, and S. H. Hussein, "Flow injection potentiometric determination of amantadine HCl.", Journal of pharmaceutical and biomedical analysis, vol. 30, issue 3, pp. 601-11, 2002 Oct 15. Abstract

New amantadine (Am) ion selective plastic membrane electrodes of both conventional and coated graphite types based on the ion-pair of amantadinium tetraphenylborate (Am-TPB) ion-pair are prepared. The conventional type electrode was fully characterized in terms of membrane composition, life span, pH, ionic strength and temperature. It was applied to potentiometric determination of amantadine in pure state and pharmaceutical preparation under batch and flow injection conditions. The selectivity of the electrode toward a large number of inorganic cations, sugars and amino acids was tested. The solubility product of the ion-pair and the formation constant of the precipitation reaction leading to the ion-pair formation were determined conductimetrically.

Abdel-Ghani, N. T., and S. H. Hussein, "Determination of ambroxol hydrochloride in pure solutions and some of its pharmaceutical preparations under batch and FIA conditions.", Farmaco (Società chimica italiana : 1989), vol. 58, issue 8, pp. 581-9, 2003 Aug. Abstract

New ambroxol (Amb) ion selective plastic membrane electrodes of both conventional and coated graphite types based on the ion-pair of ambroxolium tetraphenylborate (Amb-TPB) ion-pair are prepared. The conventional type electrode was fully characterized in terms of membrane composition, life span, pH, ionic strength and temperature. It was applied to potentiometric determination of ambroxol in pure solutions and pharmaceutical preparations under batch and flow injection conditions. The potentiometric determination was used in the determination of ambroxol in muco syrup in four batches of different expiry dates, also the amounts of ambroxol released after 1, 8 and 16 h from the muco sustained release type (S.R.) capsules were also assayed. The selectivity of the electrode toward a large number of excipient like inorganic cations, sugars and amino acids was tested. The solubility product of the ion-pair and the formation constant of the precipitation reaction leading to the ion-pair formation were determined conductimetrically.

Abdel-Ghani, N. T., A. F. A. Youssef, and M. A. Awady, "Cinchocaine hydrochloride determination by atomic absorption spectrometry and spectrophotometry.", Farmaco (Società chimica italiana : 1989), vol. 60, issue 5, pp. 419-24, 2005 May. Abstract

Two sensitive spectrophotometric and atomic absorption spectrometric procedures have been developed for determination of cinchocaine hydrochloride (Cin.Cl) in pure form and in pharmaceutical formulation. The spectrophotometric method was based on formation of an insoluble colored ion-associate between the cited drug and tetrathiocyanatocobaltate (CoTC) or hexathiocyanatochromate (CrTC) which dissolved and extracted in an organic solvent. The optimal experimental conditions for quantitative extraction such as pH, concentration of the reagents and solvent were studied. Toluene and iso-butyl alcohol proved to be the most suitable solvents for quantitative extraction of Cin-CoTC and Cin-CrTC ion-associates with maximum absorbance at 620 and 555 nm, respectively. The optimum concentration ranges, molar absorptivities, Ringbom ranges and Sandell sensitivities were also evaluated. The atomic absorption spectrometric method is based on measuring of the excess cobalt or chromium in the aqueous solution, after precipitation of the drug, at 240.7 and 357.9 nm, respectively. Linear application ranges, characteristic masses and detection limits were 57.99-361.9, 50.40 and 4.22 microg ml(-1) of Cin.Cl, in case of CoTC, while 37.99-379.9, 18.94 and 0.81 microg ml(-1) in case of CrTC.

Abdel-Ghani, N., Y. Issa, A. Shoukry, and H. Ahmed, "Flow injection analysis with tubular membrane ion-selective electrode and coated wires for buspirone hydrochloride.", Annali di chimica, vol. 97, issue 1-2, pp. 97-107, 2007 Jan-Feb. Abstract

New Plastic membrane ion-selective electrode for buspirone hydrochloride based on buspironium tetraphenylborate was prepared. The electrode exhibited mean slope of calibration graph of 58.4 mV per decade of BusCl concentration at 25 degrees C. The electrode can be used within the concentration range 6.3 x 10(-5) - 10(-2) M BusCl at a pH range of 2.5-7.0. The standard electrode potentials were determined at different temperatures and used to calculate the isothermal temperature coefficient of the electrode, amounting to 0.00056 V degrees C(-1). The electrode showed a very good selectivity for BusCl with respect to a number of inorganic cations, sugars and amino acids. The electrode was applied to the potentiometric determination of the buspirone ion and its pharmaceutical preparation under batch and flow injection conditions. Also, buspirone was determined by conductimetric titrations. Graphite rod, copper and silver coated wire electrodes were prepared and characterized as sensors for the drug under investigation.

Abdel Ghani, N. T., and A. M. Mansour, "Structural and in vitro cytotoxicity studies on 1H-benzimidazol-2-ylmethyl-N-phenyl amine and its Pd(II) and Pt(II) complexes.", Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, vol. 81, issue 1, pp. 529-43, 2011 Oct 15. Abstract

[MLCl(2)]·zH(2)O (L = (1H-benzimidazol-2-ylmethyl)-N-phenyl amine; M = Pd, z = 0; M = Pt, z = 1) and [PdL(OH(2))(2)]·2X·zH(2)O (X = Br, I, NO(3), z = 0; X = SCN, z = 1) complexes were synthesized as potential anticancer compounds and characterized by elemental analysis, spectral and thermal methods. FT-IR and (1)H NMR studies revealed that the benzimidazole L is coordinated to the metal ions via the pyridine-type nitrogen (N(py)) of the benzimidazole ring and secondary amino group (NH(sec)). Quantum mechanical calculations of energies, geometries, vibrational wavenumbers, and (1)H NMR of the benzimidazole L and its complexes were carried out by density functional theory using B3LYP functional combined with 6-31G(d) and LANL2DZ basis sets. Natural bond orbitals (NBOs) and frontier molecular orbitals were performed at B3LYP/LANL2DZ level of theory. The synthesized ligand, in comparison to its metal complexes was screened for its antibacterial activity. The benzimidazole L is more toxic against the bacterium Staphylococcus aureus (MIC = 58 μg/mL) than the standard tetracycline (MIC = 82 μg/mL). The complexes showed cytotoxicity against breast cancer, Colon Carcinoma, and human heptacellular Carcinoma cells. The platinum complex (6) displays cytotoxicity (IC(50) = 12.4 μM) against breast cancer compared with that reported for cis-platin 9.91 μM.

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